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Acarbose

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  Post Date: Jun 04,2014
  Expiry Date: Dec 01,2014
  Detailed Description: Cas No. :56180-94-0 Acarbose Acarbose [Ⅰ] CAS No. :56180 -94-0
[Alias] acarbose drugs, suppression glucosidase, Carbonell flat Glucobay
[Preparation specifications tablet: 50mg.
Pharmacology and Toxicology is a novel oral hypoglycemic agents. Competitive inhibition in the intestine glucoside hydrolase. Reduced polysaccharide and sucrose into glucose, the sugar absorption corresponding mitigation, it may have to make a meal of blood glucose lowering effect.
Generally used alone, or in combination with other oral hypoglycemic agents or insulin combined. With food, treatment of insulin-dependent and non-dependent diabetes mellitus.
Pharmacokinetics of oral gastrointestinal amylase is widely metabolism, elimination T1 / 2 of 2.8h.
[Indications] diabetes, dumping syndrome (Dumping
Adverse reactions occasional flatulence, diarrhea and other gastrointestinal disorders and itching and other skin reactions. There are also reported to cause liver damage and death.

  CAS Registry Number:

56180-94-0
  Synonyms: ;Glucobay;4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranosyl-(1->4)-alpha-D-glucopyranosyl-(1->4)-D-glucopyranose;4,6-dideoxy-4-{[(1S,4S,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranosyl-(1->4)-alpha-D-glucopyranosyl-(1->4)-beta-D-glucopyranose;4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranosyl-(1->4)-alpha-D-glucopyranosyl-(1->4)-beta-D-glucopyranose;4,6-dideoxy-4-{[4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}hexopyranosyl-(1->4)hexopyranosyl-(1->4)hexopyranose;
  Molecular Formula: C25H43NO18
  Molecular Weight: 645.6048
  Molecular Structure: 56180-94-0 acarbose

  Company: Hubei Pharmaceutical Co., Ltd. Shi Nan ninety-five     [ China ]        
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