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Cyproheptadine hydrochloride

Inquiry
  Post Date: Jan 09,2018
  Expiry Date: Jul 08,2018
  Detailed Description: Cas No. :969-33-5 Quantity: mass in stockKilograms
Specs:white powder
Price:negotiable USD Kilograms
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Description:

Cyproheptadine, sold under the brand name Periactin among others, is a first-generation antihistamine with additional anticholinergic, antiserotonergic, and local anesthetic properties.

Medical uses

Periactin (cyproheptadine)
Cyproheptadine is used to treat allergic reactions (specifically hay fever). The evidence for its use for this purpose in children is weak and ketotifen and loratadine showed equal or better results in the small trials in which they have been compared.

It is sometimes used, especially in its liquid formulation, as a preventive measure against migraine in children and adolescents, but as of 2017 the evidence for this was weak. This use is on the label in the UK and some other countries.In Australia this is the only indication for which cyproheptadine is subsidised by the PBS.

It is also used off-label in the treatment of cyclical vomiting syndrome in infants; the only evidence for this use comes from retrospective studies.

Cyproheptadine is sometimes used off label to improve akathisia in people on antipsychotic medications.

It used off-label to treat various dermatological conditions, including psychogenic itch drug-induced hyperhidrosis (excessive sweating), and prevention of blister formation for some people with epidermolysis bullosa simplex.

One of the side effects of the drug is increased appetite and weight gain, which has led to its off-label use for this purpose in children who are wasting as well as people with cystic fibrosis. The evidence for the efficacy in light of other side effects is weak.

It is sometimes used off-label in the management of moderate to severe cases of serotonin syndrome, a complex of symptoms associated with the use of serotonergic drugs, such as selective serotonin reuptake inhibitors and monoamine oxidase inhibitors), and in cases of high levels of serotonin in the blood resulting from a serotonin-producing carcinoid tumor.

  CAS Registry Number:

969-33-5

  Synonyms: ;Cyproheptadine hydrochloride anhydrous;1-Methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine hydrochloride;4-(5-Dibenzo(a,e)cycloheptatrienylidene)piperidine hydrochloride;AI3-26940;Anarexol;Antegan;Cipractin;Contrallerg;Cyproheptadiene hydrochloride;Cyproheptadine chlorhydrate;Istam;Kulinet;Kyliver;NSC 169911;Nuran;Periactin hydrochloride;Periactinol (VAN);Periactinol hydrochloride;Peritol;Sialotin;UNII-NJ82J0F8QC;VUFB3511;Vinorex;component of Dronactin;Piperidine, 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-methyl-, hydrochloride;Cyproheptadine HCl;Cyproheptadine hydrochloride;Cyproheptadine hydrocloride;4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine hydrochloride (1:1);
  Molecular Formula: C21H21N·ClH
  Molecular Weight: 323.865
  Molecular Structure: 969-33-5 Cyproheptadine hydrochloride

  Company: Hengyang Desen Biotechnology Co., Ltd.     [ China ]        
  Contact: ava
  Tel: 86-18908446905
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