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Ethisterone for anti cancer

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  Post Date: Jan 09,2017
  Expiry Date: Jan 09,2018
  Detailed Description: Cas No. :434-03-7 Ethisterone

EMAIL: cgf at chembj dot com
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Synonym: Ethinyltestosterone,Progestoral
CAS NO: 434-03-7
MF: C21H28O2
MW: 312.45
Purity: min98%
Appearance: White or kind of white crystalline powder
Certifeication: GMP, ISO 9001, USP, BP
Standard: Enterprise standard
Packaging: 1kg/tin
Usage: Synthetic progestogen; metabolite of Danazol; intermediate in the synthesis of Spironolactone

Description:

Ethisterone is a metabolite.Ethisterone is a progestogen hormone. The first orally active progestin.This compound belongs to the class of organic compounds known as androgens and derivatives. These are 3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans.
Potent progestin. Progesterone and androgen receptor antagonist.
Ethisterone is a progestogen that counteracts estrogenic proliferative effects on the endometrium.
Ethisterone is a progestogen hormone being considered to treat prostate cancer.

Application:

Chlormadinone acetate (CMA) is a derivative of naturally secreted progesterone that shows high affinity and activity at the progesterone receptor. It has an anti-estrogenic effect and, in contrast to natural progesterone, shows moderate anti-androgenic properties. CMA acts by blocking androgen receptors in target organs and by reducing the activity of skin 5alpha-reductase. It suppresses gonadotropin secretion and thereby reduces ovarian and adrenal androgen production. CMA shows high contraceptive efficacy by inhibiting ovulation due to its ability to suppress or disrupt endogenous gonadotropin secretion and, by this, inhibits follicular growth and maturation. In addition, it suppresses endometrial thickness and increases the viscosity of cervical mucus.

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  CAS Registry Number:

434-03-7

  Synonyms: ;Ethisterone,98%;17-alpha-ethynyltestosterone;pregneninolone;17a-ethynyl-17b-hydroxy-4-androsten-3-one;17a-ethynyl testosterone;anhydrohydroxyprogesterone;ethynyl testosterone;Gestoral;17-hydroxypregn-4-en-20-yn-3-one;(8xi,9xi,10xi,13xi,14xi,17alpha)-17-hydroxypregn-4-en-20-yn-3-one;(8xi,9xi,14xi,17alpha)-17-hydroxypregn-4-en-20-yn-3-one;(17alpha)-17-hydroxypregn-4-en-20-yn-3-one;
  Molecular Formula: C21H28O2
  Molecular Weight: 312.4458
  Molecular Structure: 434-03-7 ethisterone
  Hazard Symbols:  Xn:Harmful;
  Risk Codes: R40:;
R48:;
  Safety Description: S22:;
S24/25:;

  Company: Jian Jiage biological technology co, ltd     [ China ]        
  Contact: Lillian
  Tel: +8615564141272
  Fax: 053185826061
  Email: cgf@chembj.com
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