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Fludarabine phosphate

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  Post Date: Apr 14,2014
  Expiry Date: Apr 14,2015
  Detailed Description: Cas No. :75607-67-9
Name Fludarabine phosphate
Molecular Formula C10H13FN5O7P
Molecular Weight 365.21
CAS Registry Number 75607-67-9

White to off-white crystalline hygroscopic powder; soluble in acid, alkali and slightly in water
Specific of rotation: +10°~+14°(in 5mg/ml of water)
Water ≤3.0%
Heavy metals ≤0.002%
Free phosphate ≤0.1%
Sodium ≤0.2%
Chloride ≤0.2%
Total microbial count: ≤1000CFU/g
Fludarabine bisphosphate (3,5-diphosphate analog): ≤0.4%
Isoguanine: ≤0.2%
Iso-ara-guanine monophosphate: ≤0.8%
2-ethoxyphosphate analog: ≤0.2%
2-Fluoro-ara-adcnine: ≤0.2%
2-fluoroadenine: ≤0.1%
Impurity A: ≤0.1%
Impurity B: ≤0.1%
Other biggest impurity: ≤0.5%
Total impurity: ≤1.5%
Methanol: ≤2000ppm
Ethanol: ≤3000ppm
Dichloromethane: ≤600ppm
Assay (HPLC) 98.0~102.0%

For B-cell chronic lymphocytic leukemia (CLL) patients treated.

  CAS Registry Number:

75607-67-9

  Synonyms: ;Fludarabin Phosphate;9-bata-D-Arabinofuranosyl-2-fluoroadenine phosphate;9-b-D-Arabinofuranosyl-2-fluoroadenine-5-(dihydrogen phosphate);2-fluoro-9-(5-O-phosphonopentofuranosyl)-9H-purin-6-amine;2-fluoro-9-(5-O-phosphono-beta-D-arabinofuranosyl)-9H-purin-6-amine;9-beta-arabinofuranosyl-2-fluoroadenine-5'-phosphate;2-Fluoro-9-(5-O-phosphono-β-D-arabinofuranosyl)-9H-purin-6-amine;9-β-Arabinofuranosyl-2-fluoroadenine-5'-monophosphate;
  Molecular Formula: C10H13FN5O7P
  Molecular Weight: 365.2117
  Molecular Structure: 75607-67-9 Fludarabine Phosphate

  Company: kinfon pharmachem co.,ltd     [ China ]        
  Contact: kfpharma
  Tel: 0086238650081
  Fax: 0086238650081
  Email: info@kfpharmachem.com
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