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Top Quality Procaine Hydrochloride Powder CAS 51-05-8

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  Post Date: Dec 10,2016
  Expiry Date: Dec 10,2017
  Detailed Description: Cas No. :51-05-8 Quantity: 5Metric Tons
Specs:USP
Price:1 USD Metric Tons
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Top Quality Procaine Hydrochloride Powder CAS 51-05-8
1.Product Details:
Procaine hydrochloride
Product Name: procaine hydrochloride; procaine HCL; procaine;naucaine
CAS:51-05-8
MF:C13H21ClN2O2
MW:272.77
EINECS:200-077-2
Appearance:white crystalline powder
Usage:local anesthetic used as a pharmaceutical intermediate for infiltration anesthesia, nerve block
2. Description:
Procaine HCl is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade name Novocain, in some regions procaine is referred to generically as novocaine. It acts mainly by being a sodium channel blocker.Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.
Procaine HCl is indicated for the production of local or regional analgesia and anesthesia by local infiltration and peripheral nerve block techniques.
3. Applications:
Application of procaine leads to the depression of neuronal activity. The depression causes the nervous system to become hypersensitive producing restlessness and shaking, leading to minor to severe convulsions. Studies on animals have shown the use of procaine LED to the increase of dopamine and serotonin levels in the brain.Other issues may occur because of varying individual tolerance to procaine dosage. Nervousness and dizziness can arise from the excitation of the central nervous system, which may lead to respiratory failure if overdosed. Procaine may also induce weakening of the myocardium leading to cardiac arrest.
Procaine can also cause allergic reactions causing the individuals to have problems with breathing, rashes, and swelling. Allergic reactions to procaine are usually not in response to procaine itself, but to its metabolite PABA. About one in 3000 people have an atypical form of pseudocholinesterase,[citation needed] which does not hydrolyze ester anesthetics such as procaine, resulting in a prolonged period of high levels of the anesthetic in the blood and increased toxicity.

4. Specification:
Product name Procaine HCl
Appearance White crystalline powder
Assay (C13H20N2O2¡¤HCl) 99.0% to 101.0% 99.5%
Melting point 153~158ºC 156.5~157.0ºC
Heavy metals ¡Ü20ppm <5ppm
Acidity ¡Ü0.02N NaOH 0.5ml 0.3ml
Chromatographic purity Secondary spots¡Ü0.5%,sum¡Ü1.0% Conforms
Loss on drying ¡Ü1.0% 0.06%
Residue on ignition ¡Ü0.15% 0.03%
Bacterial endotoxins ¡Ü0.6EU/mg <0.6EU/mg

5.Related Hot Products:
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Lidocaine hydrochloride CAS: 73-78-9
Tetracaine hydrochloride CAS: 136-47-0
Procaine hydrochloride CAS: 51-05-8
Tetracaine CAS: 94-24-6

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  CAS Registry Number:

51-05-8

  Synonyms: ;2-(Diethylamino)ethyl 4-aminobenzoate;Procaine Hcl;ATOXICAINE;2-(diethylamino)ethyl 4-aminobenzoate hydrochloride (1:1);2-methylpropyl 4-aminobenzoate hydrochloride;
  Molecular Formula: C13H21ClN2O2
  Molecular Weight: 272.771
  Molecular Structure: 51-05-8 Procaine hydrochloride
  Hazard Symbols:  T:Toxic;
  Risk Codes: R25:;
R36/37/38:;
  Safety Description: S26:;
S37/39:;
S45:;

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