(2E)-2-(1,3-BENZOTHIAZOL-2-YL)-3-[4-(DIMETHYLAMINO)PHENYL]ACRYLONITRILE [112632-96-9]

(2E)-2-(1,3-BENZOTHIAZOL-2-YL)-3-[4-(DIMETHYLAMINO)PHENYL]ACRYLONITRILE

6-methoxyquinolin-8-amine; (4-phenylpiperazin-1-yl)(3,4,5-trimethoxyphenyl)methanone; ethyl 5-hydroxy-2-methyl-1-benzofuran-3-carboxylate; 4,7-dimethyl-2H,5H-pyrano[4,3-b]pyran-2,5-dione; N-(3-nitrophenyl)quinoline-8-sulfonamide; 1,3-benzodioxol-5-yl[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]methanone; dimethyl 4-(furan-2-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; 3-amino-2-methyl-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one; 3,4,5-trimethoxy-N-[4-(morpholin-4-yl)phenyl]benzamide; 1,4-bis(phenylsulfonyl)piperazine; 2,2'-(methanediyldisulfanediyl)bis(1,3-benzothiazole); 1,4-bis[(4-methylphenyl)sulfonyl]piperazine; [(4-nitrobenzyl)sulfanyl]acetic acid; 2-(4-fluorophenyl)-1,3-benzothiazole; 1,4-bis[(4-bromophenyl)sulfonyl]piperazine; 3-[(4-nitrobenzyl)sulfanyl]propanoic acid; 2-(1,3-thiazol-2-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione; 1-(1,3-benzothiazol-2-ylsulfanyl)propan-2-one; N-[(E)-1,3-benzodioxol-5-ylmethylidene]-4-(morpholin-4-yl)aniline; 4-methyl-N-(3-nitrophenyl)benzenesulfonamide; 3-hydroxy-6-(hydroxymethyl)-2-(morpholin-4-ylmethyl)-4H-pyran-4-one; N-(2-bromophenyl)benzenesulfonamide; 2-(benzylsulfanyl)benzoic acid; 3,3'-(phenylmethanediyl)bis(2-methyl-1H-indole); 2-(tetrahydrofuran-2-ylmethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione; phenyl(pyridin-2-yl)methanol; 2-(prop-2-yn-1-ylsulfanyl)-1,3-benzothiazole; N-[3-(morpholin-4-yl)propyl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-amine; (2-thioxo-1,3-benzothiazol-3(2H)-yl)acetic acid; 2-(2,2-dimethoxyethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione; 7-(morpholin-4-ylmethyl)quinolin-8-ol; 1-(4-methoxyphenyl)-2,3-di(morpholin-4-yl)-3-phenylpropan-1-one; 2-[(4-nitrobenzyl)sulfanyl]-1,3-benzoxazole; 2-[(4-nitrobenzyl)sulfanyl]-1,3-benzothiazole; 1-(1,3-benzoxazol-2-ylsulfanyl)propan-2-one; 4-methyl-N-[2-(morpholin-4-yl)ethyl]benzenesulfonamide; 1-phenyl-2-(1H-1,2,4-triazol-5-ylsulfanyl)ethanone; 1-phenyl-2-[(5-phenyl-1H-1,2,4-triazol-3-yl)sulfanyl]ethanone; 1-[(2,4,6-trimethylphenyl)sulfonyl]-1H-benzimidazole; 2-[(4-nitrophenoxy)methyl]-1,3-benzothiazole; 1,3-benzodioxol-5-yl[2-(prop-2-yn-1-ylsulfanyl)-1H-benzimidazol-1-yl]methanone; N-(1,3-benzodioxol-5-ylmethyl)-4-fluorobenzenesulfonamide; N-(1,3-benzodioxol-5-ylmethyl)-3-chloro-1-benzothiophene-2-carboxamide; 2-(1,3-benzoxazol-2-ylsulfanyl)-1-(3-nitrophenyl)ethanone; 1-[(4-fluorophenyl)sulfonyl]-4-(2-methoxyphenyl)piperazine; 2-[2-(1H-benzotriazol-1-yl)-2-oxoethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione; 2-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-2-oxoethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione; 4-methyl-3-(methylsulfanyl)-5-(thiophen-2-yl)-4H-1,2,4-triazole; dimethyl 2,6-dimethyl-4-(thiophen-2-yl)-1,4-dihydropyridine-3,5-dicarboxylate; 4-[(E)-2-nitroethenyl]phenol; 2,4,6-trimethyl-N-(pyridin-3-yl)benzenesulfonamide; 1-(naphthalen-2-ylsulfonyl)-1H-benzimidazole; 1,3-benzodioxol-5-yl[4-(4-fluorophenyl)piperazin-1-yl]methanone; 3-chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-6-methoxy-1-benzothiophene-2-carboxamide; ethyl 4-(quinolin-8-ylsulfonyl)piperazine-1-carboxylate; 1-benzyl-4-(thiophen-2-ylsulfonyl)piperazine; 2-[(pyridin-3-ylcarbonyl)amino]ethyl thiophene-2-carboxylate; 1-(thiophen-2-ylsulfonyl)-2,3-dihydro-1H-indole; 2-[(pyridin-3-ylcarbonyl)amino]ethyl 4-(morpholin-4-ylsulfonyl)benzoate; ethyl 4-[(4-fluorophenyl)sulfonyl]piperazine-1-carboxylate; (4-phenylpiperazin-1-yl)[4-(piperidin-1-ylsulfonyl)phenyl]methanone; 8-(2,3-dihydro-1H-indol-1-ylsulfonyl)quinoline; 1,3-benzodioxol-5-yl(4-phenylpiperazin-1-yl)methanone; 2-{[5-(1,3-benzodioxol-5-yl)-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone; N-[4-({[4-(prop-2-en-1-yl)-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetyl)phenyl]benzenesulfonamide; 5-(furan-2-yl)-2-(4-methoxyphenyl)-5,6-dihydro-7H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one; methyl 4-{[(4-fluorophenyl)sulfonyl]amino}benzoate; 1,3-benzodioxol-5-yl(2,3-dihydro-1H-indol-1-yl)methanone; N-[2-(morpholin-4-yl)ethyl]naphthalene-2-sulfonamide; 2-[(4-nitrobenzyl)sulfanyl]pyridine-3-carboxylic acid; N-(1,3-benzodioxol-5-yl)-3-chloro-6-fluoro-1-benzothiophene-2-carboxamide; ethyl 2-[(1,3-benzodioxol-5-ylcarbonyl)amino]-4,5-dimethylthiophene-3-carboxylate; N-(2-fluorophenyl)-2-(morpholin-4-yl)acetamide; 5-amino-1-[4-(4-fluorophenyl)phthalazin-1-yl]-1H-pyrazole-4-carbonitrile; 5-phenyl-4-(pyrrolidin-1-yl)thieno[2,3-d]pyrimidine; 2-(6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-ylsulfanyl)-N-(5-methyl-1,2-oxazol-3-yl)acetamide; 6-methyl-4-(4-methylpiperazin-1-yl)-5-phenylthieno[2,3-d]pyrimidine; 1-[1-(3-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(morpholin-4-yl)ethanone; N-(3-cyano-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl)pyridine-3-carboxamide; (2E)-3-(3-nitrophenyl)-1-(piperidin-1-yl)prop-2-en-1-one; 2,4,6-trimethyl-N-(pyridin-3-ylmethyl)benzenesulfonamide; 3-nitro-N-(4-phenyl-1,3-thiazol-2-yl)benzamide; (3-chloro-6-methoxy-1-benzothiophen-2-yl)(2,3-dihydro-1H-indol-1-yl)methanone; 4-[(furan-2-ylmethyl)sulfamoyl]benzoic acid; (2E)-3-(3-{[(2,4,6-trimethylphenyl)sulfonyl]amino}phenyl)prop-2-enoic acid; (2E)-3-(3-nitrophenyl)-N-(pyridin-3-ylmethyl)prop-2-enamide; 2-oxo-2-phenylethyl (1,3-benzoxazol-2-ylsulfanyl)acetate; (2E)-3-[4-methoxy-3-(morpholin-4-ylsulfonyl)phenyl]prop-2-enoic acid; (2E)-3-[3-(benzylsulfamoyl)-4-methoxyphenyl]prop-2-enoic acid; N-(1-ethyl-2-oxo-1,2-dihydrobenzo[cd]indol-6-yl)pyridine-4-carboxamide; ethyl (2E)-2-cyano-3-(furan-2-yl)prop-2-enoate; (2E)-1-(morpholin-4-yl)-3-(3-nitrophenyl)prop-2-en-1-one; N-(4-acetylphenyl)benzenesulfonamide; 1-[(4-fluorophenyl)sulfonyl]-3,5-dimethyl-1H-pyrazole; 2-(1,3-benzoxazol-2-ylsulfanyl)-1-phenylethanone; 1,3-benzodioxol-5-yl(3,5-dimethyl-1H-pyrazol-1-yl)methanone; 2-[(4-nitrobenzyl)sulfanyl]-1H-benzimidazole; 2-[(6-ethoxy-1,3-benzothiazol-2-yl)sulfanyl]-1-(4-fluorophenyl)ethanone; isoquinolin-1-yl(4-methoxyphenyl)methanone; (2E)-3-[3-(4-chlorophenyl)imidazo[1,5-a]pyridin-1-yl]prop-2-enoic acid; 3-chloro-6-methoxy-1-benzothiophene-2-carboxylic acid; 3-(3-nitrophenyl)imidazo[1,5-a]pyridine-1-carbaldehyde; 3-(2-chlorophenyl)imidazo[1,5-a]pyridine-1-carbaldehyde; (2E)-3-[3-(2-chlorophenyl)imidazo[1,5-a]pyridin-1-yl]prop-2-enoic acid; 5-(quinolin-8-ylsulfanyl)furan-2-carbaldehyde; 6-(aminomethyl)benzo[cd]indol-2(1H)-one; {[4-phenyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid; 8-(azepan-1-ylsulfonyl)quinoline; 2-(thiophen-2-ylsulfonyl)-1,2,3,4-tetrahydroisoquinoline; (4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl pyridine-3-carboxylate; N-[3-(trifluoromethyl)phenyl]-3,4-dihydroisoquinoline-2(1H)-carbothioamide; 1-(quinolin-8-ylsulfonyl)piperidine-4-carboxylic acid; methyl 4-[(quinolin-8-ylsulfonyl)amino]benzoate; 4-nitro-N-(pyridin-3-ylmethyl)benzenesulfonamide; 3-(1,3-benzothiazol-2-yl)-8-methoxy-2H-chromen-2-one; 4-fluoro-N-[(2-oxo-1,2-dihydrobenzo[cd]indol-6-yl)methyl]benzamide; 2-methoxy-N-[(2-oxo-1,2-dihydrobenzo[cd]indol-6-yl)methyl]benzamide; 2-methyl-N-[(2-oxo-1,2-dihydrobenzo[cd]indol-6-yl)methyl]benzamide; N-[(2-oxo-1,2-dihydrobenzo[cd]indol-6-yl)methyl]propanamide; 4-chloro-N-(4-phenyl-1,3-thiazol-2-yl)benzamide; ethyl 5-(acetyloxy)-2-methylnaphtho[1,2-b]furan-3-carboxylate; 1,3-benzothiazol-2-ylmethyl diethylcarbamodithioate; 6,7,8,9-tetrahydrodibenzo[b,d]furan-2-yl thiophene-2-carboxylate; N-(4-phenylthiophen-2-yl)furan-2-carboxamide; N-[5-ethyl-3-(morpholin-4-ylmethyl)thiophen-2-yl]benzamide; {[4-(prop-2-en-1-yl)-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid; {[5-(1,3-benzodioxol-5-yl)-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid; 1-(phenylsulfonyl)-1H-benzimidazole; 2-(1,3-benzodioxol-5-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione; 3-methyl-1-(5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl)-1H-pyrazol-5-amine; 3-(4-methoxyphenyl)imidazo[1,5-a]pyridine-1-carbaldehyde; 3-(2-fluorophenyl)imidazo[1,5-a]pyridine-1-carbaldehyde; N-(5-methyl-1,2-oxazol-3-yl)-2-[(1-phenyl-1H-tetrazol-5-yl)sulfanyl]acetamide; 3,5-dimethyl-1-(naphthalen-2-ylsulfonyl)-1H-pyrazole; 1-(4-fluorophenyl)-2-[(6-nitro-1,3-benzothiazol-2-yl)sulfanyl]ethanone; 1-[(4-chlorophenyl)sulfonyl]-4-phenylpiperazine; 1-[(4-fluorophenyl)sulfonyl]-4-phenylpiperazine; N-(1,3-benzothiazol-2-yl)-4-methoxybenzenesulfonamide; 1-[(4-nitrophenyl)sulfonyl]-1H-benzimidazole; 1-[(2-nitrophenyl)sulfonyl]-1H-benzimidazole; 4-(naphthalen-2-yloxy)-2-(pyridin-3-yl)quinazoline; ethyl 2-amino-4-(4-fluorophenyl)-5-methylthiophene-3-carboxylate; ethyl 4-hydroxy-1-[3-(trifluoromethyl)phenyl]-1H-pyrazole-3-carboxylate; ethyl 1-(3-chloro-4-fluorophenyl)-4-hydroxy-1H-pyrazole-3-carboxylate; 5-(4-chlorophenyl)-6-methylthieno[2,3-d]pyrimidin-4(3H)-one; 5-(4-fluorophenyl)-6-methylthieno[2,3-d]pyrimidin-4(3H)-one; ethyl 4-hydroxy-1-[4-(methoxycarbonyl)phenyl]-1H-pyrazole-3-carboxylate; N-(4-tert-butylphenyl)-2-([1,2,4]triazolo[4,3-a]pyridin-3-ylsulfanyl)acetamide; N-(furan-2-ylmethyl)quinoline-8-sulfonamide; (2E)-3-{4-methoxy-3-[(pyridin-3-ylmethyl)sulfamoyl]phenyl}prop-2-enoic acid; (3,5-dimethyl-1H-pyrazol-1-yl)[4-(morpholin-4-ylsulfonyl)phenyl]methanone; (3-chloro-6-methoxy-1-benzothiophen-2-yl)(3,5-dimethyl-1H-pyrazol-1-yl)methanone; 1-(4-methoxyphenyl)-4-(thiophen-2-ylsulfonyl)piperazine; 1-[(4-bromophenyl)sulfonyl]piperazine; 4-methyl-3-[(2-phenylethyl)sulfanyl]-5-(thiophen-2-yl)-4H-1,2,4-triazole; {[4-(4-methoxyphenyl)-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid; 2-({4-ethyl-5-[(quinolin-8-yloxy)methyl]-4H-1,2,4-triazol-3-yl}sulfanyl)acetamide; 2-{[5-(3-chloro-1-benzothiophen-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide; 3-(3,6-dichloro-1-benzothiophen-2-yl)-4-ethyl-5-(methylsulfanyl)-4H-1,2,4-triazole; (2E)-1-[4-(3-chlorophenyl)piperazin-1-yl]-3-(4-fluorophenyl)prop-2-en-1-one; (2E)-1-(2,3-dihydro-1H-indol-1-yl)-3-(3-fluorophenyl)prop-2-en-1-one; 2-({5-[(1,3-benzodioxol-5-yloxy)methyl]-4-ethyl-4H-1,2,4-triazol-3-yl}sulfanyl)acetamide; ({4-methyl-5-[(quinolin-8-yloxy)methyl]-4H-1,2,4-triazol-3-yl}sulfanyl)acetic acid; N-(4-acetylphenyl)-4-(pyridin-2-yl)piperazine-1-carbothioamide; 1-(4-fluorophenyl)-4-[(4-fluorophenyl)sulfonyl]piperazine; ethyl 4-(thiophen-2-ylsulfonyl)piperazine-1-carboxylate; 8-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)quinoline; {[4-phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid; 1H-benzimidazol-1-yl(3-chloro-6-methoxy-1-benzothiophen-2-yl)methanone; N-{4-[(pyridin-2-ylmethyl)sulfamoyl]phenyl}acetamide; ethyl 2-{[(2E)-3-(furan-2-yl)prop-2-enoyl]amino}-4,5-dimethylthiophene-3-carboxylate; 8-methyl-2-[(3-nitrophenoxy)methyl]imidazo[1,2-a]pyridine; 5-(4-bromophenyl)thieno[2,3-d]pyrimidine-4(3H)-thione; {[5-(furan-2-yl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid; 7-[(4-methylpiperazin-1-yl)methyl]quinolin-8-ol; 7-[(4-ethylpiperazin-1-yl)methyl]quinolin-8-ol; 2,3-dihydro-1H-indol-1-yl(3,4,5-trimethoxyphenyl)methanone; N-(1,3-benzodioxol-5-ylmethyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine; ethyl 2-{[(2E)-3-(furan-2-yl)prop-2-enoyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; 1-[(4-fluorophenyl)sulfonyl]-4-(pyridin-2-yl)piperazine; 1-(4-chlorophenyl)-2-{[4-methyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; (2E)-3-(3-{[(4-methylphenyl)sulfonyl]amino}phenyl)prop-2-enoic acid; (2E)-3-(4-methoxyphenyl)-1-(morpholin-4-yl)prop-2-en-1-one; 2-{[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl}benzoic acid; 1-({4-[(E)-2-carboxyethenyl]phenyl}sulfonyl)piperidine-4-carboxylic acid; 5-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)-2-methoxybenzoic acid; 5-[(furan-2-ylmethyl)sulfamoyl]-2-methoxybenzoic acid; ethyl 4-{[(E)-2-phenylethenyl]sulfonyl}piperazine-1-carboxylate; ethyl 4-(phenylsulfonyl)piperazine-1-carboxylate; methyl 4-[(naphthalen-2-ylsulfonyl)amino]benzoate; methyl 4-({[(E)-2-phenylethenyl]sulfonyl}amino)benzoate; 5-[(2-hydroxyethyl)(methyl)sulfamoyl]-2-methoxybenzoic acid; 1-(phenylsulfonyl)piperidine-4-carboxylic acid; 1-[(4-chlorophenyl)sulfonyl]piperidine-4-carboxylic acid; 1-[(4-fluorophenyl)sulfonyl]piperidine-4-carboxylic acid; 1-phenyl-4-(thiophen-2-ylsulfonyl)piperazine; 2-[4-(thiophen-2-ylsulfonyl)piperazin-1-yl]pyrimidine; 4-(4-fluorophenyl)-N-(4-methoxyphenyl)piperazine-1-carbothioamide; (2E)-N-(1,3-benzothiazol-2-yl)-3-(4-methoxyphenyl)prop-2-enamide; 3,6-dichloro-1-benzothiophene-2-carboxylic acid; 1,3-benzodioxol-5-yl[4-(3-chlorophenyl)piperazin-1-yl]methanone; 2-[4-(dimethylamino)phenyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione; (2E)-N-(1,3-benzothiazol-2-yl)-3-(4-fluorophenyl)prop-2-enamide; 2-{[2-(3-nitrophenyl)-2-oxoethyl]sulfanyl}pyridine-3-carboxylic acid; 2-{[(8-methylimidazo[1,2-a]pyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole; ethyl 4-[(4-chlorophenyl)sulfonyl]piperazine-1-carboxylate; N-(1,3-benzothiazol-2-yl)-2,4,6-trimethylbenzenesulfonamide; ethyl 2-[(phenylcarbamoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; N-[3-(piperidin-1-ylmethyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]acetamide; 2-({[(E)-2-phenylethenyl]sulfonyl}amino)benzoic acid; 2-{[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl}pyridine-3-carboxylic acid; ethyl {[4-phenyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetate; 1-[(4-methylphenyl)sulfonyl]-1H-benzimidazole; 2-[(6-nitro-1,3-benzothiazol-2-yl)sulfanyl]-1-phenylethanone; (2E)-3-(4-methoxyphenyl)-N-(4-phenyl-1,3-thiazol-2-yl)prop-2-enamide; imidazo[1,2-a]pyridin-2-ylmethyl diethylcarbamodithioate; 2-(1,3-benzoxazol-2-ylsulfanyl)-1-(4-methoxyphenyl)ethanone; 6-(4-methylphenyl)[1,3]thiazolo[2,3-c][1,2,4]triazole-3(2H)-thione; 8-(morpholin-4-ylsulfonyl)quinoline; methyl 3-chloro-6-methoxy-1-benzothiophene-2-carboxylate; 4-methoxy-N-[4-(morpholin-4-yl)phenyl]benzenesulfonamide; N-(furan-2-ylmethyl)-4-nitrobenzenesulfonamide; 1-(4-fluorophenyl)-4-(thiophen-2-ylsulfonyl)piperazine; 1,3-benzodioxol-5-yl[4-(4-methoxyphenyl)piperazin-1-yl]methanone; (2E)-3-[4-(pyridin-3-ylsulfamoyl)phenyl]prop-2-enoic acid; (2E)-3-(3,4-dimethoxyphenyl)-N-[2-(morpholin-4-yl)ethyl]prop-2-enamide; N-(furan-2-ylmethyl)-4-(piperidin-1-ylsulfonyl)benzamide; 4-(pyrrolidin-1-ylsulfonyl)benzoic acid; 4-{[(4-methoxyphenyl)sulfonyl]amino}benzoic acid; (2E)-3-{3-[(furan-2-ylmethyl)sulfamoyl]-4-methoxyphenyl}prop-2-enoic acid; 2-{[(4-carboxyphenyl)sulfonyl]amino}benzoic acid; N-[4-(morpholin-4-ylsulfamoyl)phenyl]acetamide; (2E)-3-(4-fluorophenyl)-N-[4-(morpholin-4-yl)phenyl]prop-2-enamide; 4-[(pyridin-3-ylmethyl)sulfamoyl]benzoic acid; (2E)-3-(4-methoxyphenyl)-N-(pyridin-3-ylmethyl)prop-2-enamide; 4-(1,3-benzothiazol-2-ylsulfamoyl)benzoic acid; 2-{[2-(4-fluorophenyl)-2-oxoethyl]sulfanyl}benzoic acid; 1-[(3-carboxy-4-methoxyphenyl)sulfonyl]piperidine-4-carboxylic acid; 1-[(2,4,6-trimethylphenyl)sulfonyl]pyrrolidin-2-one; 3-[bis(2-hydroxyethyl)sulfamoyl]-4-methylbenzoic acid; (E)-N-(3-nitrophenyl)-2-phenylethenesulfonamide; 2,4,6-trimethyl-N-(3-nitrophenyl)benzenesulfonamide; 1-[(4-fluorophenyl)sulfonyl]-2,3-dihydro-1H-indole; N-(1,3-benzothiazol-2-yl)thiophene-2-sulfonamide; 8-(piperidin-1-ylsulfonyl)quinoline; 1-(3-chlorophenyl)-4-(thiophen-2-ylsulfonyl)piperazine; 3,5-dimethyl-1-(thiophen-2-ylsulfonyl)-1H-pyrazole; 6-amino-1-ethylbenzo[cd]indol-2(1H)-one; 4-(1,3-benzodioxol-5-ylmethyl)-N-ethylpiperazine-1-carbothioamide; (2E)-1-(2,3-dihydro-1H-indol-1-yl)-3-(4-fluorophenyl)prop-2-en-1-one; 2-hydroxy-4-[(quinolin-8-ylsulfonyl)amino]benzoic acid; (2E)-3-{4-[(furan-2-ylmethyl)sulfamoyl]phenyl}prop-2-enoic acid; N-(1,3-benzothiazol-2-yl)quinoline-8-sulfonamide; (2E)-3-(4-methoxyphenyl)-1-(piperidin-1-yl)prop-2-en-1-one; 2-oxo-2-phenylethyl (1,3-benzothiazol-2-ylsulfanyl)acetate; 2-[2-(1H-1,2,4-triazol-5-ylsulfanyl)ethyl]-1H-isoindole-1,3(2H)-dione; 4-fluoro-N-[4-(morpholin-4-yl)phenyl]benzenesulfonamide; (2E)-N-(1,3-benzodioxol-5-ylmethyl)-3-(thiophen-2-yl)prop-2-enamide; N-[4-(morpholin-4-yl)phenyl]-1,3-benzodioxole-5-carboxamide; (2E)-3-[4-methoxy-3-(pyrrolidin-1-ylsulfonyl)phenyl]prop-2-enoic acid; 1-[(4-chlorophenyl)sulfonyl]-4-(pyridin-2-yl)piperazine; methyl 4-{[(4-chlorophenyl)sulfonyl]amino}benzoate; 4-{[(4-carboxyphenyl)sulfonyl]amino}-2-hydroxybenzoic acid; 8-(1H-benzimidazol-1-ylsulfonyl)quinoline; 6-ethoxy-2-[(4-nitrobenzyl)sulfanyl]-1,3-benzothiazole; 2-(4-chlorophenyl)-2-oxoethyl (2E)-3-(furan-2-yl)prop-2-enoate; N-(4-acetylphenyl)-2-nitrobenzenesulfonamide; 4-methyl-N-[4-(morpholin-4-yl)phenyl]benzenesulfonamide; N-[4-(morpholin-4-yl)phenyl]benzenesulfonamide; 1-[(4-chlorophenyl)sulfonyl]-3,5-dimethyl-1H-pyrazole; 2-(3-nitrophenyl)-2-oxoethyl (2E)-3-(furan-2-yl)prop-2-enoate; 2-oxo-2-phenylethyl (2E)-3-(furan-2-yl)prop-2-enoate; N-(4-acetylphenyl)-2,4,6-trimethylbenzenesulfonamide; N-(4-fluorophenyl)-4-(4-methoxyphenyl)piperazine-1-carbothioamide; 4-(1,3-benzodioxol-5-ylmethyl)-N-methylpiperazine-1-carbothioamide; 4-(4-fluorophenyl)-N-(2-methoxyphenyl)piperazine-1-carbothioamide; N-(2-methoxyphenyl)-4-phenylpiperazine-1-carbothioamide; N-(4-chlorophenyl)-4-(pyridin-2-yl)piperazine-1-carbothioamide; 1,3-benzodioxol-5-yl[4-(2-fluorophenyl)piperazin-1-yl]methanone; 1-phenyl-2-{[4-(prop-2-en-1-yl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 5-[bis(2-hydroxyethyl)sulfamoyl]-2-methoxybenzoic acid; 1-phenyl-2-{[4-(prop-2-en-1-yl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; (2E)-3-(4-fluorophenyl)-1-[4-(pyridin-2-yl)piperazin-1-yl]prop-2-en-1-one; N-(4-chloro-2-fluorophenyl)quinoline-8-sulfonamide; 4-(benzylsulfamoyl)benzoic acid; [(6-nitro-1,3-benzothiazol-2-yl)sulfanyl]acetic acid; 2-[(4-nitrobenzyl)sulfanyl]-4,5-dihydro-1,3-thiazole; 1-(4-fluorophenyl)-2-[4-(4-methoxyphenyl)piperazin-1-yl]ethanone; 6,7,8,9-tetrahydrodibenzo[b,d]furan-2-yl furan-2-carboxylate; (3,6-dichloro-1-benzothiophen-2-yl)(3,5-dimethyl-1H-pyrazol-1-yl)methanone; (2E)-3-(3-{[(4-methoxyphenyl)sulfonyl]amino}phenyl)prop-2-enoic acid; (2E)-3-[4-methoxy-3-(piperidin-1-ylsulfonyl)phenyl]prop-2-enoic acid; 4-({3-[(E)-2-carboxyethenyl]phenyl}sulfamoyl)benzoic acid; N-(4-methoxyphenyl)-4-(pyridin-2-yl)piperazine-1-carbothioamide; N-(4-methoxyphenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide; 1-(2-fluorophenyl)-4-[(4-fluorophenyl)sulfonyl]piperazine; 2-(naphthalen-2-ylsulfonyl)-1,2,3,4-tetrahydroisoquinoline; 4-methoxy-N-(pyridin-3-ylmethyl)benzenesulfonamide; 1-(naphthalen-2-ylsulfonyl)piperidine-4-carboxylic acid; 6-(4-chlorophenyl)[1,3]thiazolo[3,2-b][1,2,4]triazole; N-(1,3-benzodioxol-5-yl)naphthalene-2-sulfonamide; 1-(5-hydroxy-2-methylnaphtho[1,2-b]furan-3-yl)ethanone; ethyl 4-(naphthalen-2-ylsulfonyl)piperazine-1-carboxylate; 1-(4-chlorophenyl)-2-{[4-methyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 2-{[4-methyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone; 3-[(difluoromethyl)sulfanyl]-4-(4-methoxyphenyl)-5-(thiophen-2-yl)-4H-1,2,4-triazole; 4-(4-methoxyphenyl)-3-(methylsulfanyl)-5-(thiophen-2-yl)-4H-1,2,4-triazole; 3-[(difluoromethyl)sulfanyl]-4-phenyl-5-(thiophen-2-yl)-4H-1,2,4-triazole; 3-(methylsulfanyl)-4-phenyl-5-(thiophen-2-yl)-4H-1,2,4-triazole; N-(1,2-oxazol-3-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide; 2-[(biphenyl-4-yloxy)methyl]imidazo[1,2-a]pyridine; 2-({4-methyl-5-[(quinolin-8-yloxy)methyl]-4H-1,2,4-triazol-3-yl}sulfanyl)acetamide; 5-(2,3-dihydro-1H-indol-1-ylsulfonyl)-2-methoxybenzoic acid; [3-(2-hydroxyethyl)-5,6-dimethyl-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl](phenyl)methanone; 2-(1,3-benzothiazol-2-ylsulfanyl)-1-(3-nitrophenyl)ethanone; (2E)-1-[4-(4-fluorophenyl)piperazin-1-yl]-3-(thiophen-2-yl)prop-2-en-1-one; (2E)-1-[4-(2-fluorophenyl)piperazin-1-yl]-3-(thiophen-2-yl)prop-2-en-1-one; 2-{4-[(4-fluorophenyl)sulfonyl]piperazin-1-yl}pyrimidine; (2E)-3-{4-[(pyridin-3-ylmethyl)sulfamoyl]phenyl}prop-2-enoic acid; 4-(3-chlorophenyl)-N-methylpiperazine-1-carbothioamide; 4-fluoro-N-(2,3,4,9-tetrahydro-1H-carbazol-6-yl)benzamide; 3-methoxy-N-(2,3,4,9-tetrahydro-1H-carbazol-6-yl)benzamide; N-(2,3,4,9-tetrahydro-1H-carbazol-6-yl)furan-2-carboxamide; 5-chloroquinolin-8-yl phenylcarbamate; 2-{[4-phenyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide; 4-(2-fluorophenyl)-N-methylpiperazine-1-carbothioamide; 4-(2-fluorophenyl)-N-(2-methoxyphenyl)piperazine-1-carbothioamide; 4-(4-methoxyphenyl)-N-methylpiperazine-1-carbothioamide; 4-(2-fluorophenyl)-N-(3-methoxyphenyl)piperazine-1-carbothioamide; 4-(4-fluorophenyl)-N-methylpiperazine-1-carbothioamide; 2-{[4-methyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide; 2-{[4-(2,3-dimethylphenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide; 2-{[4-(4-chlorophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide; ({4-ethyl-5-[(quinolin-8-yloxy)methyl]-4H-1,2,4-triazol-3-yl}sulfanyl)acetic acid; 2-{[5-(3,4-dimethoxyphenyl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide; 2-{[4-(4-methoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide; 2-{[4-methyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide; 2-{[4-ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide; 2-{[4-methyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide; N-(4-methoxybenzyl)quinoline-8-sulfonamide; methyl {[5-(1,3-benzodioxol-5-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetate; (2E)-N-(1,3-benzodioxol-5-ylmethyl)-3-phenylprop-2-enamide; (2E)-N-(1,3-benzodioxol-5-ylmethyl)-3-(4-fluorophenyl)prop-2-enamide; 2-oxo-2-phenylethyl (2E)-3-(3-nitrophenyl)prop-2-enoate; 2-methyl-5-(piperidin-1-ylsulfonyl)benzoic acid; N-[(E)-1,3-benzodioxol-5-ylmethylidene]-1-(pyridin-3-yl)methanamine; 4-(morpholin-4-yl)-N-[(E)-pyridin-3-ylmethylidene]aniline; 1-methyl-4-(naphthalen-2-ylsulfonyl)piperazine; 2-methyl-5-(morpholin-4-ylsulfonyl)benzoic acid; 4-[(1,3-benzodioxol-5-ylmethyl)sulfamoyl]benzoic acid; 4-[(thiophen-2-ylsulfonyl)amino]benzoic acid; 2-{[2-(biphenyl-4-yl)-2-oxoethyl]sulfanyl}benzoic acid; (2E)-3-{3-[(thiophen-2-ylsulfonyl)amino]phenyl}prop-2-enoic acid; 4-methoxy-N-[4-(morpholin-4-yl)phenyl]benzamide; 1-phenyl-4-{[(E)-2-phenylethenyl]sulfonyl}piperazine; 1-[(4-methoxy-3-nitrophenyl)sulfonyl]-1H-benzimidazole; N-(4-chlorophenyl)-4-(4-fluorophenyl)piperazine-1-carbothioamide; 1-(4-fluorophenyl)-4-{[(E)-2-phenylethenyl]sulfonyl}piperazine; 1-{[(E)-2-phenylethenyl]sulfonyl}-2,3-dihydro-1H-indole; 1-benzyl-4-{[(E)-2-phenylethenyl]sulfonyl}piperazine; 1,3-benzodioxol-5-ylmethyl 1,3-benzodioxole-5-carboxylate; 4-nitrobenzyl (2E)-3-(thiophen-2-yl)prop-2-enoate; N-(4-chloro-2-fluorophenyl)-4-phenylpiperazine-1-carbothioamide; (2E)-1-(2,3-dihydro-1H-indol-1-yl)-3-(thiophen-2-yl)prop-2-en-1-one; 4-(2-fluorophenyl)-N-(4-methoxyphenyl)piperazine-1-carbothioamide; 1-(naphthalen-2-ylsulfonyl)-2,3-dihydro-1H-indole; N-(1,3-benzodioxol-5-yl)-1,3-benzodioxole-5-carboxamide; 1-(4-methoxyphenyl)-4-(propylsulfonyl)piperazine; 1-(3-chlorophenyl)-4-(propylsulfonyl)piperazine; 1-(propylsulfonyl)-4-(pyridin-2-yl)piperazine; 2-{[4-ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone; 1-(4-fluorophenyl)-2-{[4-methyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 2-[(2-phenylethyl)sulfanyl]pyridine-3-carboxylic acid; 3-(1,3-benzodioxol-5-yl)-4-methyl-5-[(2-phenylethyl)sulfanyl]-4H-1,2,4-triazole; 1-(4-fluorophenyl)-2-{[4-methyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; N-(4-methoxyphenyl)-4-(pyrimidin-2-yl)piperazine-1-carbothioamide; 3-{4-methyl-5-[(4-nitrobenzyl)sulfanyl]-4H-1,2,4-triazol-3-yl}pyridine; N-[(2-carbamoylphenyl)carbamothioyl]-4-methoxybenzamide; 1-(2-fluorophenyl)-4-(thiophen-2-ylsulfonyl)piperazine; 2-[4-(3-chlorophenyl)piperazin-1-yl]acetamide; (2E)-1-[4-(3-chlorophenyl)piperazin-1-yl]-3-(thiophen-2-yl)prop-2-en-1-one; 1H-benzotriazol-1-yl(3-chloro-6-methoxy-1-benzothiophen-2-yl)methanone; 1-[(4-methyl-3-nitrophenyl)sulfonyl]-1H-benzimidazole; (2E)-1-(3,4-dihydroquinolin-1(2H)-yl)-3-(thiophen-2-yl)prop-2-en-1-one; 1,3-benzodioxol-5-ylmethyl (2E)-3-(thiophen-2-yl)prop-2-enoate; 2-(4-chlorophenyl)-2-oxoethyl (2E)-3-(thiophen-2-yl)prop-2-enoate; 2-[(8-hydroxy-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-9-yl)carbonyl]benzoic acid; 2-(1,3-benzoxazol-2-ylsulfanyl)-1-(4-fluorophenyl)ethanone; 2-{[4-ethyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-fluorophenyl)ethanone; 2-{[4-(prop-2-en-1-yl)-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide; 3-chloro-6-methoxy-1-benzothiophene-2-carbohydrazide; (2E)-3-[4-(pyrrolidin-1-ylsulfonyl)phenyl]prop-2-enoic acid; [(6-ethoxy-1,3-benzothiazol-2-yl)sulfanyl]acetic acid; 1-(4-chlorophenyl)-2-[(4-phenyl-4H-1,2,4-triazol-3-yl)sulfanyl]ethanone; 2-oxo-2-phenylethyl (2E)-3-(thiophen-2-yl)prop-2-enoate; 1-phenyl-2-{[4-(prop-2-en-1-yl)-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; (2E)-1-[4-(pyridin-2-yl)piperazin-1-yl]-3-(thiophen-2-yl)prop-2-en-1-one; 2-[(imidazo[1,2-a]pyridin-2-ylmethoxy)methyl]-1,3-benzothiazole; N-(5-ethylthiophen-2-yl)benzamide; ethyl 2-(acetylamino)-4-(pyridin-3-yl)thiophene-3-carboxylate; (7-methylimidazo[1,2-a]pyridin-2-yl)methyl diethylcarbamodithioate; ethyl 4-bromo-5-hydroxy-2-methylnaphtho[1,2-b]furan-3-carboxylate; 5-[(4-methylpiperidin-1-yl)methyl]quinolin-8-ol; 7-methyl-2-[(pyrimidin-2-ylsulfanyl)methyl]imidazo[1,2-a]pyridine; 2-{[(7-methylimidazo[1,2-a]pyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole; (7-methylimidazo[1,2-a]pyridin-2-yl)methyl morpholine-4-carbodithioate; (5-methylimidazo[1,2-a]pyridin-2-yl)methyl (pyridin-3-ylmethyl)carbamodithioate; 3-(thiophen-2-yl)imidazo[1,5-a]pyridine-1-carbaldehyde; 3-(4-fluorophenyl)imidazo[1,5-a]pyridine-1-carbaldehyde; 2-(4-nitrophenyl)-2-oxoethyl (2E)-3-(thiophen-2-yl)prop-2-enoate; N-[4,5-dimethyl-3-(pyrrolidin-1-ylmethyl)thiophen-2-yl]benzamide; N-[4,5-dimethyl-3-(morpholin-4-ylmethyl)thiophen-2-yl]benzamide; N-{4,5-dimethyl-3-[(4-methylpiperidin-1-yl)methyl]thiophen-2-yl}benzamide; N-{4,5-dimethyl-3-[(4-methylpiperazin-1-yl)methyl]thiophen-2-yl}benzamide; (3-cyclopentyl-5,6-dimethyl-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl)(phenyl)methanone; (3-tert-butyl-5,6-dimethyl-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl)(phenyl)methanone; [5,6-dimethyl-3-(3-methylbutyl)-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl](phenyl)methanone; 5-[(1,3-benzodioxol-5-yloxy)methyl]-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione; 4-(azepan-1-ylsulfonyl)-N-(1,2-oxazol-3-yl)benzamide; 2-[4-(pyrrolidin-1-ylsulfonyl)phenyl]-1,3-benzothiazole; N-[2-(trifluoromethyl)phenyl]-3,4-dihydroisoquinoline-2(1H)-carbothioamide; N-(5-chloro-2-methoxyphenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide; 4-methyl-N-(1,2-oxazol-3-yl)-3-(piperidin-1-ylsulfonyl)benzamide; 3-[(2-hydroxyethyl)(methyl)sulfamoyl]-4-methylbenzoic acid; N-(1,3-benzodioxol-5-yl)-2-methylquinoline-8-sulfonamide; 2-[(4-methyl-5-{[(2-methylquinolin-8-yl)oxy]methyl}-4H-1,2,4-triazol-3-yl)sulfanyl]acetamide; {[4-(2,3-dimethylphenyl)-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid; 1-[(3-carboxyphenyl)sulfonyl]piperidine-4-carboxylic acid; 3-[(difluoromethyl)sulfanyl]-5-(phenoxymethyl)-4H-1,2,4-triazol-4-amine; 2-[3-(pyrrolidin-1-ylsulfonyl)phenyl]-1,3-benzothiazole; 2-({[4-methyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}methyl)-1,3-benzothiazole; N-(4-acetylphenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide; 3-[(furan-2-ylmethyl)sulfamoyl]benzoic acid; 2-methyl-8-{[4-methyl-5-(methylsulfanyl)-4H-1,2,4-triazol-3-yl]methoxy}quinoline; [(4-methyl-5-{[(2-methylquinolin-8-yl)oxy]methyl}-4H-1,2,4-triazol-3-yl)sulfanyl]acetic acid; 8-[(3,5-dimethyl-1H-pyrazol-1-yl)sulfonyl]-2-methylquinoline; N-(1,2-oxazol-3-yl)-3-(pyrrolidin-1-ylsulfonyl)benzamide; 3-[(difluoromethyl)sulfanyl]-4-(2,3-dimethylphenyl)-5-(thiophen-2-yl)-4H-1,2,4-triazole; 1-[(5-carboxy-2-methylphenyl)sulfonyl]piperidine-4-carboxylic acid; (3,5-dimethyl-1H-pyrazol-1-yl)[4-(pyrrolidin-1-ylsulfonyl)phenyl]methanone; 4-[(4-methylpiperidin-1-yl)sulfonyl]-N-(1,2-oxazol-3-yl)benzamide; (3,5-dimethyl-1H-pyrazol-1-yl)[4-(piperidin-1-ylsulfonyl)phenyl]methanone; 1-(4-chlorophenyl)-2-[4-(2-fluorophenyl)piperazin-1-yl]ethanone; N,N-dimethyl-2-[(1-phenyl-1H-tetrazol-5-yl)sulfanyl]acetamide; 4,4'-diethyl-5,5'-bis(methylsulfanyl)-4H,4'H-3,3'-bi-1,2,4-triazole; 2-methyl-8-{[5-(methylsulfanyl)-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl]methoxy}quinoline; 5-chloro-8-{[4-ethyl-5-(methylsulfanyl)-4H-1,2,4-triazol-3-yl]methoxy}quinoline; 3-(azepan-1-ylsulfonyl)-N-(1,2-oxazol-3-yl)benzamide; 8-(3,4-dihydroquinolin-1(2H)-ylsulfonyl)-2-methylquinoline; (3,4-dimethoxyphenyl)[2-(methylsulfanyl)-1H-benzimidazol-1-yl]methanone; (3,5-dimethyl-1H-pyrazol-1-yl)[3-(piperidin-1-ylsulfonyl)phenyl]methanone; {[4-phenyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid; ethyl 4,5-dimethyl-2-[(3,4,5-trimethoxybenzoyl)amino]thiophene-3-carboxylate; 5-chloro-7-[(4-methylpiperazin-1-yl)methyl]quinolin-8-yl 4-methylbenzoate; 5-chloro-7-[(4-methylpiperazin-1-yl)methyl]quinolin-8-yl thiophene-2-carboxylate; 4-(1,3-benzodioxol-5-ylmethyl)-N-(4-methoxyphenyl)piperazine-1-carbothioamide; (3,6-dichloro-1-benzothiophen-2-yl)[4-(4-fluorophenyl)piperazin-1-yl]methanone; ethyl 2-[(1,3-benzodioxol-5-ylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; methyl {[4-methyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetate; 2-{[5-(1,3-benzodioxol-5-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(biphenyl-4-yl)ethanone; 1-(biphenyl-4-yl)-2-{[4-methyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 1-(2,4-dichlorophenyl)-2-{[4-methyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; [4-(azepan-1-ylsulfonyl)phenyl][4-(pyridin-2-yl)piperazin-1-yl]methanone; 2-{[5-(3-chloro-1-benzothiophen-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-fluorophenyl)ethanone; 2-{[5-(3-chloro-1-benzothiophen-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-chlorophenyl)ethanone; methyl {[5-(3-chloro-1-benzothiophen-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetate; N-(4-acetylphenyl)-4-(2-fluorophenyl)piperazine-1-carbothioamide; N-(4-acetylphenyl)-4-(2-methoxyphenyl)piperazine-1-carbothioamide; [4-(diphenylmethyl)piperazin-1-yl][4-(pyrrolidin-1-ylsulfonyl)phenyl]methanone; 2-({5-[(1,3-benzodioxol-5-yloxy)methyl]-4-phenyl-4H-1,2,4-triazol-3-yl}sulfanyl)-1-(4-chlorophenyl)ethanone; 2-({5-[(1,3-benzodioxol-5-yloxy)methyl]-4-ethyl-4H-1,2,4-triazol-3-yl}sulfanyl)-1-(4-chlorophenyl)ethanone; 2-({5-[(1,3-benzodioxol-5-yloxy)methyl]-4-ethyl-4H-1,2,4-triazol-3-yl}sulfanyl)-1-(4-fluorophenyl)ethanone; 2-({5-[(1,3-benzodioxol-5-yloxy)methyl]-4-ethyl-4H-1,2,4-triazol-3-yl}sulfanyl)-1-phenylethanone; [4-(2-fluorophenyl)piperazin-1-yl][4-(piperidin-1-ylsulfonyl)phenyl]methanone; N-[4-(difluoromethoxy)phenyl]-4-(2-fluorophenyl)piperazine-1-carbothioamide; 4-(3-chlorophenyl)-N-[4-(difluoromethoxy)phenyl]piperazine-1-carbothioamide; [4-(azepan-1-ylsulfonyl)phenyl][4-(2-fluorophenyl)piperazin-1-yl]methanone; N-[2-(difluoromethoxy)phenyl]-4-(2-methoxyphenyl)piperazine-1-carbothioamide; (3-chloro-6-fluoro-1-benzothiophen-2-yl)[4-(3-chlorophenyl)piperazin-1-yl]methanone; (3-chloro-6-fluoro-1-benzothiophen-2-yl)[4-(2-fluorophenyl)piperazin-1-yl]methanone; 2-(2-{[4-phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethyl)-1H-isoindole-1,3(2H)-dione; 3-chloro-N-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]-6-methoxy-1-benzothiophene-2-carboxamide; ethyl 2-{[(3-chloro-6-methoxy-1-benzothiophen-2-yl)carbonyl]amino}-4,5-dimethylthiophene-3-carboxylate; N-{3-[(4-ethylpiperazin-1-yl)methyl]-4,5-dimethylthiophen-2-yl}benzamide; N-(3-{[4-(2-hydroxyethyl)piperazin-1-yl]methyl}-4,5-dimethylthiophen-2-yl)benzamide; N-{3-[(4-benzylpiperazin-1-yl)methyl]-4,5-dimethylthiophen-2-yl}benzamide; N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3-(pyrrolidin-1-ylsulfonyl)benzamide; N-[4-(morpholin-4-yl)phenyl]-3-(pyrrolidin-1-ylsulfonyl)benzamide; 2-oxo-2-phenylethyl 1-(quinolin-8-ylsulfonyl)piperidine-4-carboxylate; 8-{[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]oxy}quinoline; [4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl][4-(piperidin-1-ylsulfonyl)phenyl]methanone; N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-4-fluorobenzenesulfonamide; ethyl 2-({[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetyl}amino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; 2-(4-methoxyphenyl)-2-oxoethyl 1-(quinolin-8-ylsulfonyl)piperidine-4-carboxylate; 2-(4-chlorophenyl)-2-oxoethyl 1-(quinolin-8-ylsulfonyl)piperidine-4-carboxylate; (2E)-3-[3-(2,3-dihydro-1H-indol-1-ylsulfonyl)-4,5-dimethoxyphenyl]prop-2-enoic acid; 2-(4-chlorophenyl)-2-oxoethyl 1-(naphthalen-2-ylsulfonyl)piperidine-4-carboxylate; ethyl 2-({(2E)-3-[4-methoxy-3-(piperidin-1-ylsulfonyl)phenyl]prop-2-enoyl}amino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; 2-(4-fluorophenyl)-2-oxoethyl (1,3-benzothiazol-2-ylsulfanyl)acetate; N-[4-(morpholin-4-yl)phenyl]-1-(phenylsulfonyl)cyclopropanecarboxamide; 4-(azepan-1-ylsulfonyl)-N-(1,3-benzodioxol-5-ylmethyl)benzamide; ethyl 5-acetyl-2-{[4-(azepan-1-ylsulfonyl)benzoyl]amino}-4-methylthiophene-3-carboxylate; ethyl 2-{[4-(azepan-1-ylsulfonyl)benzoyl]amino}-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate; [4-(azepan-1-ylsulfonyl)phenyl](4-phenylpiperazin-1-yl)methanone; N-(3-chloro-4-fluorophenyl)-2-[(2-methyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl)sulfanyl]acetamide; 2-(4-fluorophenyl)-2-oxoethyl 1-(quinolin-8-ylsulfonyl)piperidine-4-carboxylate; N-(4-chlorophenyl)-2-{[5-(5-methylfuran-2-yl)-4-oxo-3-(prop-2-en-1-yl)-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]sulfanyl}acetamide; N-(4-chlorophenyl)-2-{[5-(5-methylfuran-2-yl)-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]sulfanyl}acetamide; N-(4-ethoxyphenyl)-2-{[5-(5-methylfuran-2-yl)-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]sulfanyl}acetamide; N-(3-methoxyphenyl)-2-{[5-(5-methylfuran-2-yl)-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]sulfanyl}acetamide; N-(2-methoxyphenyl)-2-{[5-(5-methylfuran-2-yl)-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]sulfanyl}acetamide; N-(2-methoxyphenyl)-2-{[5-(5-methylfuran-2-yl)-4-oxo-3-(prop-2-en-1-yl)-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]sulfanyl}acetamide; N-(2,5-dimethylphenyl)-2-{[5-(5-methylfuran-2-yl)-4-oxo-3-(prop-2-en-1-yl)-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]sulfanyl}acetamide; N-(2,5-dimethylphenyl)-2-{[5-(5-methylfuran-2-yl)-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]sulfanyl}acetamide; N-(3,4-dimethylphenyl)-2-{[5-(5-methylfuran-2-yl)-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]sulfanyl}acetamide; N-(2,6-dichlorophenyl)-2-{[5-(5-methylfuran-2-yl)-4-oxo-3-(prop-2-en-1-yl)-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]sulfanyl}acetamide; N-(1,3-benzodioxol-5-yl)-2-{[5-(5-methylfuran-2-yl)-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]sulfanyl}acetamide; 2-{[5-(5-methylfuran-2-yl)-4-oxo-3-(prop-2-en-1-yl)-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]sulfanyl}-N-[3-(trifluoromethyl)phenyl]acetamide; 2-{[5-(5-methylfuran-2-yl)-4-oxo-3-(prop-2-en-1-yl)-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]sulfanyl}-N-[2-(trifluoromethyl)phenyl]acetamide; 5-(5-methylfuran-2-yl)-2-{[2-oxo-2-(pyrrolidin-1-yl)ethyl]sulfanyl}-3-(prop-2-en-1-yl)thieno[2,3-d]pyrimidin-4(3H)-one; ethyl 2-({[(4-chlorophenyl)sulfanyl]acetyl}amino)-4-(5-methylfuran-2-yl)thiophene-3-carboxylate; 2-{[2-(4-fluorophenyl)-2-oxoethyl]sulfanyl}-5-(5-methylfuran-2-yl)-3-(prop-2-en-1-yl)thieno[2,3-d]pyrimidin-4(3H)-one; 5-(5-methylfuran-2-yl)-2-{[2-(naphthalen-2-yl)-2-oxoethyl]sulfanyl}-3-(prop-2-en-1-yl)thieno[2,3-d]pyrimidin-4(3H)-one; 2-{[5-(5-methylfuran-2-yl)-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]sulfanyl}-N-phenylacetamide; 2-{[5-(5-methylfuran-2-yl)-4-oxo-3-(prop-2-en-1-yl)-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]sulfanyl}-N-phenylacetamide; 2-{[5-(5-methylfuran-2-yl)-4-oxo-3-(prop-2-en-1-yl)-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]sulfanyl}-N-(4-methylphenyl)acetamide; 1-(4-fluorophenyl)-2-{[4-phenyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 1-(4-fluorophenyl)-2-{[4-(prop-2-en-1-yl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 1-(4-chlorophenyl)-2-{[4-(prop-2-en-1-yl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 2-(4-fluorophenyl)-2-oxoethyl 2-phenylquinoline-4-carboxylate; ethyl 2-[(2-fluorobenzoyl)amino]-4-(4-methoxyphenyl)-5-methylthiophene-3-carboxylate; 2-{[5-(3-chloro-1-benzothiophen-2-yl)-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone; ethyl 2-{[(2E)-3-(4-fluorophenyl)prop-2-enoyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; ethyl 4,5-dimethyl-2-{[4-(morpholin-4-ylsulfonyl)benzoyl]amino}thiophene-3-carboxylate; 2-(4-chlorophenyl)-2-oxoethyl (1,3-benzoxazol-2-ylsulfanyl)acetate; 2-(4-chlorophenyl)-2-oxoethyl 4-[(furan-2-ylmethyl)sulfamoyl]benzoate; 1-phenyl-2-{[4-phenyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; methyl {[4-(4-methoxyphenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetate; 2-{[4-(4-methoxyphenyl)-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone; 4-{4-(4-methoxyphenyl)-5-[(2-phenylethyl)sulfanyl]-4H-1,2,4-triazol-3-yl}pyridine; 1-(2,4-dichlorophenyl)-2-{[4-(4-methoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; methyl ({4-(prop-2-en-1-yl)-5-[(quinolin-8-yloxy)methyl]-4H-1,2,4-triazol-3-yl}sulfanyl)acetate; 1-phenyl-2-({4-(prop-2-en-1-yl)-5-[(quinolin-8-yloxy)methyl]-4H-1,2,4-triazol-3-yl}sulfanyl)ethanone; methyl ({4-ethyl-5-[(quinolin-8-yloxy)methyl]-4H-1,2,4-triazol-3-yl}sulfanyl)acetate; 1-(4-fluorophenyl)-2-{[4-(4-methoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 1-(4-chlorophenyl)-2-{[4-(4-methoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 2-(2-{[4-(4-methoxyphenyl)-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethyl)-1H-isoindole-1,3(2H)-dione; 2-{[5-(1,3-benzodioxol-5-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone; 1-(4-chlorophenyl)-2-({4-ethyl-5-[(quinolin-8-yloxy)methyl]-4H-1,2,4-triazol-3-yl}sulfanyl)ethanone; 1-(2,4-dichlorophenyl)-2-({4-ethyl-5-[(quinolin-8-yloxy)methyl]-4H-1,2,4-triazol-3-yl}sulfanyl)ethanone; 2-({4-ethyl-5-[(quinolin-8-yloxy)methyl]-4H-1,2,4-triazol-3-yl}sulfanyl)-1-(4-fluorophenyl)ethanone; 8-({4-ethyl-5-[(2-phenylethyl)sulfanyl]-4H-1,2,4-triazol-3-yl}methoxy)quinoline; [4-(2-fluorophenyl)piperazin-1-yl][4-(morpholin-4-ylsulfonyl)phenyl]methanone; 1-(3-chlorophenyl)-4-[(4-fluorophenyl)sulfonyl]piperazine; 3-chloro-N-[4-(morpholin-4-yl)phenyl]-1-benzothiophene-2-carboxamide; 4-chloro-N-(4-phenyl-1,3-thiazol-2-yl)benzenesulfonamide; N-(1-ethyl-2-oxo-1,2-dihydrobenzo[cd]indol-6-yl)-3-nitrobenzamide; ethyl 2-{[(2E)-3-(4-methoxyphenyl)prop-2-enoyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; ethyl 2-{[(2E)-3-(3-nitrophenyl)prop-2-enoyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; 5-amino-1-[5-(3,4-dimethylphenyl)thieno[2,3-d]pyrimidin-4-yl]-1H-pyrazole-4-carbonitrile; (2E)-1-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-3-phenylprop-2-en-1-one; 4-{4-phenyl-5-[(2-phenylethyl)sulfanyl]-4H-1,2,4-triazol-3-yl}pyridine; diethyl 3-methyl-5-[(morpholin-4-ylacetyl)amino]thiophene-2,4-dicarboxylate; 1-(naphthalen-2-ylsulfonyl)-4-phenylpiperazine; 2-{[4-methyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone; 1-(4-methoxyphenyl)-2-{[4-(prop-2-en-1-yl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; methyl 4-({[4-(2-fluorophenyl)piperazin-1-yl]carbothioyl}amino)benzoate; 1-phenyl-2-{[4-phenyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; N-(1,3-benzodioxol-5-yl)-4-(morpholin-4-ylsulfonyl)benzamide; [4-(4-fluorophenyl)piperazin-1-yl][4-(morpholin-4-ylsulfonyl)phenyl]methanone; N-[3-(difluoromethoxy)phenyl]-4-(4-methoxyphenyl)piperazine-1-carbothioamide; {[5-(3-chloro-1-benzothiophen-2-yl)-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid; N-[3-(difluoromethoxy)phenyl]-4-(pyridin-2-yl)piperazine-1-carbothioamide; diethyl 5-{[(2E)-3-(4-methoxyphenyl)prop-2-enoyl]amino}-3-methylthiophene-2,4-dicarboxylate; ethyl 5-acetyl-2-{[(2E)-3-(4-methoxyphenyl)prop-2-enoyl]amino}-4-methylthiophene-3-carboxylate; ethyl 2-{[(2E)-3-(4-methoxyphenyl)prop-2-enoyl]amino}-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate; (4-phenylpiperazin-1-yl)[4-(pyrrolidin-1-ylsulfonyl)phenyl]methanone; 5-(morpholin-4-ylmethyl)quinolin-8-ol; 5-[(4-ethylpiperazin-1-yl)methyl]quinolin-8-ol; 5-[(4-phenylpiperazin-1-yl)methyl]quinolin-8-ol; N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)naphthalene-2-sulfonamide; 2-({4-phenyl-5-[(quinolin-8-yloxy)methyl]-4H-1,2,4-triazol-3-yl}sulfanyl)acetamide; 1-phenyl-2-({4-phenyl-5-[(quinolin-8-yloxy)methyl]-4H-1,2,4-triazol-3-yl}sulfanyl)ethanone; 2-[4-(morpholin-4-yl)phenyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione; diethyl 5-{[(2E)-3-(4-fluorophenyl)prop-2-enoyl]amino}-3-methylthiophene-2,4-dicarboxylate; ethyl 2-{[4-(morpholin-4-ylsulfonyl)benzoyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; 2-(3-nitrophenyl)-2-oxoethyl 4-(piperidin-1-ylsulfonyl)benzoate; (2E)-N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-(4-methoxyphenyl)prop-2-enamide; 4-(morpholin-4-ylsulfonyl)-N-(4-phenyl-1,3-thiazol-2-yl)benzamide; 2-{[2-(4-bromophenyl)-2-oxoethyl]sulfanyl}benzoic acid; ethyl 2-{[(2E)-3-(4-methoxyphenyl)prop-2-enoyl]amino}-4,5-dimethylthiophene-3-carboxylate; 2-[(6-ethoxy-1,3-benzothiazol-2-yl)sulfanyl]-1-(3-nitrophenyl)ethanone; (2E)-3-{3-[(1,3-benzodioxol-5-ylmethyl)sulfamoyl]-4-methoxyphenyl}prop-2-enoic acid; 2-oxo-2-phenylethyl 4-(piperidin-1-ylsulfonyl)benzoate; (2E)-3-(3,4-dimethoxyphenyl)-N-[4-(morpholin-4-yl)phenyl]prop-2-enamide; (2E)-3-{3-[(quinolin-8-ylsulfonyl)amino]phenyl}prop-2-enoic acid; 2-oxo-2-phenylethyl 2-phenylquinoline-4-carboxylate; 1,3-benzodioxol-5-ylmethyl 4-(piperidin-1-ylsulfonyl)benzoate; [4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl](3-chloro-1-benzothiophen-2-yl)methanone; 4-[({5-[(E)-2-carboxyethenyl]-2-methoxyphenyl}sulfonyl)amino]benzoic acid; 2-[({5-[(E)-2-carboxyethenyl]-2-methoxyphenyl}sulfonyl)amino]benzoic acid; N-[4-(morpholin-4-yl)phenyl]-4-(piperidin-1-ylsulfonyl)benzamide; N-[4-(morpholin-4-yl)phenyl]-4-(morpholin-4-ylsulfonyl)benzamide; N-[4-(morpholin-4-yl)phenyl]-2,2-diphenylacetamide; 1-(1,3-benzodioxol-5-ylmethyl)-4-[(4-chlorophenyl)sulfonyl]piperazine; 2-{[4-methyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone; 2-{[4-(4-methoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone; 3,4-dihydroisoquinolin-2(1H)-yl[4-(pyrrolidin-1-ylsulfonyl)phenyl]methanone; 2-{[5-(3,4-dimethoxyphenyl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone; N-[6-(methylsulfonyl)-1,3-benzothiazol-2-yl]-1,3-benzodioxole-5-carboxamide; 3,4,5-trimethoxy-N-[6-(methylsulfonyl)-1,3-benzothiazol-2-yl]benzamide; 1-(1,3-benzodioxol-5-ylmethyl)-4-[(4-fluorophenyl)sulfonyl]piperazine; 1-phenyl-2-{[4-phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 2-[2-(4-benzylpiperazin-1-yl)-2-oxoethyl]-1H-isoindole-1,3(2H)-dione; N-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]-3,4,5-trimethoxybenzamide; 2-{[4-ethyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide; 1-(4-methoxyphenyl)-2-{[4-phenyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; [4-(azepan-1-ylsulfonyl)phenyl](2,3-dihydro-1H-indol-1-yl)methanone; 5-[(1,3-benzodioxol-5-ylmethyl)sulfamoyl]-2-methoxybenzoic acid; 8-{[4-(4-fluorophenyl)piperazin-1-yl]sulfonyl}quinoline; (4-methylpiperidin-1-yl)[4-(morpholin-4-ylsulfonyl)phenyl]methanone; 3-chloro-6-methoxy-N-[4-(morpholin-4-yl)phenyl]-1-benzothiophene-2-carboxamide; N-(1,3-benzodioxol-5-ylmethyl)-3-chloro-6-methoxy-1-benzothiophene-2-carboxamide; [4-(morpholin-4-ylsulfonyl)phenyl](4-phenylpiperazin-1-yl)methanone; 1,3-benzodioxol-5-ylmethyl 4-(morpholin-4-ylsulfonyl)benzoate; N-(1,3-benzodioxol-5-ylmethyl)-1-(phenylsulfonyl)cyclopropanecarboxamide; [4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl][4-(morpholin-4-ylsulfonyl)phenyl]methanone; 5-[(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)sulfamoyl]-2-methoxybenzoic acid; 2-(4-fluorophenyl)-2-oxoethyl 1-(naphthalen-2-ylsulfonyl)piperidine-4-carboxylate; 2-(4-methoxyphenyl)-2-oxoethyl 1-(naphthalen-2-ylsulfonyl)piperidine-4-carboxylate; ethyl 4,5-dimethyl-2-({[1-(phenylsulfonyl)cyclopropyl]carbonyl}amino)thiophene-3-carboxylate; (4-phenylpiperazin-1-yl)[1-(phenylsulfonyl)cyclopropyl]methanone; 3,4-dihydroquinolin-1(2H)-yl[4-(pyrrolidin-1-ylsulfonyl)phenyl]methanone; N-(1,3-benzodioxol-5-ylmethyl)-4-(pyrrolidin-1-ylsulfonyl)benzamide; 2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-1-(4-fluorophenyl)ethanone; N-(1,3-benzodioxol-5-yl)-4-(piperidin-1-ylsulfonyl)benzamide; 1-(4-fluorophenyl)-2-[(5-methyl[1,2,4]triazolo[4,3-a]quinolin-1-yl)sulfanyl]ethanone; 1-[(4-fluorophenyl)sulfonyl]-4-(4-methoxyphenyl)piperazine; N-(1,3-benzodioxol-5-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide; N-(1,3-benzothiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide; 2-{[4-ethyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone; 1-(4-chlorophenyl)-2-{[4-ethyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 2-{[5-(3-chloro-6-methoxy-1-benzothiophen-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide; 2-{[5-(3-chloro-6-methoxy-1-benzothiophen-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone; (3-chloro-6-fluoro-1-benzothiophen-2-yl)[4-(4-fluorophenyl)piperazin-1-yl]methanone; ethyl 4-[(3-chloro-6-fluoro-1-benzothiophen-2-yl)carbonyl]piperazine-1-carboxylate; 1-(4-chlorophenyl)-2-{[5-(3,4-dimethoxyphenyl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 2-{[4-ethyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-fluorophenyl)ethanone; N-(3-acetylphenyl)-4-(2-fluorophenyl)piperazine-1-carbothioamide; ethyl 4-{[2-(benzoylamino)-4,5-dimethylthiophen-3-yl]methyl}piperazine-1-carboxylate; N-{4,5-dimethyl-3-[(4-phenylpiperazin-1-yl)methyl]thiophen-2-yl}benzamide; N-(3-{[4-(4-fluorophenyl)piperazin-1-yl]methyl}-4,5-dimethylthiophen-2-yl)benzamide; N-[3-(3,4-dihydroisoquinolin-2(1H)-ylmethyl)-4,5-dimethylthiophen-2-yl]benzamide; {3-[2-(diethylamino)ethyl]-5,6-dimethyl-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl}(phenyl)methanone; [5,6-dimethyl-3-(2,2,6,6-tetramethylpiperidin-4-yl)-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl](phenyl)methanone; {5,6-dimethyl-3-[2-(morpholin-4-yl)ethyl]-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl}(phenyl)methanone; ethyl 4,5-dimethyl-2-{[3-(piperidin-1-ylsulfonyl)benzoyl]amino}thiophene-3-carboxylate; [4-(3-chlorophenyl)piperazin-1-yl][3-(morpholin-4-ylsulfonyl)phenyl]methanone; [4-(3-chlorophenyl)piperazin-1-yl][3-(piperidin-1-ylsulfonyl)phenyl]methanone; 2-oxo-2-phenylethyl {[4-phenyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetate; 2-{[5-(1,3-benzodioxol-5-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(2,4-dichlorophenyl)ethanone; 4-(4-methoxyphenyl)-3-[(2-phenylethyl)sulfanyl]-5-(thiophen-2-yl)-4H-1,2,4-triazole; 3-(3-chloro-1-benzothiophen-2-yl)-4-methyl-5-[(2-phenylethyl)sulfanyl]-4H-1,2,4-triazole; 2-{[5-(3-chloro-1-benzothiophen-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-nitrophenyl)ethanone; 2-{[5-(3-chloro-1-benzothiophen-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone; 1-(2,4-dichlorophenyl)-2-{[4-methyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 2-[4-(piperidin-1-ylsulfonyl)phenyl]-1,3-benzothiazole; N-(2,6-dimethylphenyl)-2-[(7-methoxy-4-methylquinolin-2-yl)sulfanyl]acetamide; 2-[(4-methoxybenzoyl)amino]-5-phenylthiophene-3-carboxamide; methyl 2-{[3-(morpholin-4-yl)propanoyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; 4-(3-chlorophenyl)-N-[2-(difluoromethoxy)phenyl]piperazine-1-carbothioamide; N-(5-methyl-1,2-oxazol-3-yl)-2-[(4-oxo-3-phenyl-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl)sulfanyl]acetamide; 2-(6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-ylsulfanyl)-1-(2-methyl-1H-indol-3-yl)ethanone; 5-chloro-7-[(4-methylpiperazin-1-yl)methyl]quinolin-8-yl 3-nitrobenzoate; 2-[(4-iodophenoxy)methyl]imidazo[1,2-a]pyrimidine; 2-{[5-(5-methylfuran-2-yl)-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]sulfanyl}-N-(2-phenylethyl)acetamide; N-(2-methoxyphenyl)-2-([1,2,4]triazolo[3,4-b][1,3]benzothiazol-3-ylsulfanyl)acetamide; 5-(4-fluorophenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]-6-methylthieno[2,3-d]pyrimidine; ethyl 4-(4-chlorophenyl)-2-[(thiophen-2-ylcarbonyl)amino]thiophene-3-carboxylate; methyl 2-{[([1,2,4]triazolo[4,3-a]pyridin-3-ylsulfanyl)acetyl]amino}-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate; [2-(methylsulfanyl)-1H-benzimidazol-1-yl][4-(piperidin-1-ylsulfonyl)phenyl]methanone; {[5-(3,6-dichloro-1-benzothiophen-2-yl)-4-ethyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid; 2-{[5-(3,6-dichloro-1-benzothiophen-2-yl)-4-ethyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide; 4-(1,3-benzodioxol-5-ylmethyl)-N-[4-(difluoromethoxy)phenyl]piperazine-1-carbothioamide; N-[2-(difluoromethoxy)phenyl]-4-(4-methoxyphenyl)piperazine-1-carbothioamide; 2-({5-[(1,3-benzodioxol-5-yloxy)methyl]-4-ethyl-4H-1,2,4-triazol-3-yl}sulfanyl)-1-(2,4-dichlorophenyl)ethanone; 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-ethyl-5-[(4-nitrobenzyl)sulfanyl]-4H-1,2,4-triazole; 3-(2,5-dimethyl-1H-pyrrol-1-yl)-5-[4-(propan-2-yl)phenyl]thieno[2,3-d]pyrimidin-4(3H)-one; 3-[5-(ethoxycarbonyl)-6-methyl-2H-furo[3',2':3,4]naphtho[2,1-e][1,3]oxazin-3(4H)-yl]propanoic acid; 4-[5-(ethoxycarbonyl)-6-methyl-2H-furo[3',2':3,4]naphtho[2,1-e][1,3]oxazin-3(4H)-yl]butanoic acid; 3-(morpholin-4-ylmethyl)-1,2-diphenylindolizine; 1-(4-methoxyphenyl)-2-[(6-nitro-1,3-benzothiazol-2-yl)sulfanyl]ethanone; 1-(4-methoxyphenyl)-2-{[4-(prop-2-en-1-yl)-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 3-[(4-nitrobenzyl)sulfanyl]-4-(prop-2-en-1-yl)-5-(thiophen-2-yl)-4H-1,2,4-triazole; 1-(4-fluorophenyl)-2-{[4-(prop-2-en-1-yl)-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; (3,6-dichloro-1-benzothiophen-2-yl)[4-(4-methoxyphenyl)piperazin-1-yl]methanone; 2-[(4,5-diphenyl-1H-imidazol-2-yl)sulfanyl]-1-(4-fluorophenyl)ethanone; 1-(4-methoxyphenyl)-4-{[(E)-2-phenylethenyl]sulfonyl}piperazine; ethyl 2-{[4-(azepan-1-ylsulfonyl)benzoyl]amino}-4,5-dimethylthiophene-3-carboxylate; (2E)-3-[4-methoxy-3-(pyridin-3-ylsulfamoyl)phenyl]prop-2-enoic acid; 2-{[(1-bromonaphthalen-2-yl)oxy]methyl}-5-methylimidazo[1,2-a]pyridine; 1-(4-chlorophenyl)-2-{[4-phenyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 4-(1,3-benzodioxol-5-ylmethyl)-N-(2-methoxyphenyl)piperazine-1-carbothioamide; 2-(4-chlorophenyl)-2-oxoethyl 2-phenylquinoline-4-carboxylate; {[5-(1,3-benzodioxol-5-yl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid; 4-(1,3-benzodioxol-5-ylmethyl)-N-(4-chlorophenyl)piperazine-1-carbothioamide; [4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl](3,6-dichloro-1-benzothiophen-2-yl)methanone; 3,4-dihydroisoquinolin-2(1H)-yl[4-(morpholin-4-ylsulfonyl)phenyl]methanone; 5-bromo-N-[(2-methoxyphenyl)carbamothioyl]furan-2-carboxamide; 1-(4-fluorophenyl)-2-{[4-phenyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; (2E)-N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-(3,4-dimethoxyphenyl)prop-2-enamide; ethyl 4,5-dimethyl-2-{[4-(piperidin-1-ylsulfonyl)benzoyl]amino}thiophene-3-carboxylate; diethyl 3-methyl-5-{[(2E)-3-(thiophen-2-yl)prop-2-enoyl]amino}thiophene-2,4-dicarboxylate; 2-{[2-(1,3-benzodioxol-5-yl)-2-oxoethyl]sulfanyl}-5-(5-methylfuran-2-yl)-3-(prop-2-en-1-yl)thieno[2,3-d]pyrimidin-4(3H)-one; 5-(5-methylfuran-2-yl)-2-[(2-oxo-2-phenylethyl)sulfanyl]-3-phenylthieno[2,3-d]pyrimidin-4(3H)-one; 1-(4-fluorophenyl)-2-{[4-methyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 2-{[5-(1,3-benzodioxol-5-yl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(3-nitrophenyl)ethanone; 2-{[5-(1,3-benzodioxol-5-yl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-fluorophenyl)ethanone; N-(1-benzylpiperidin-4-yl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-amine; 3-aminopyrazine-2-carbohydrazide; 2-[4-(naphthalen-2-ylsulfonyl)piperazin-1-yl]pyrimidine; ethyl 2-{[3-(azepan-1-ylsulfonyl)benzoyl]amino}-4,5-dimethylthiophene-3-carboxylate; 2-{[4-methyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-nitrophenyl)ethanone; 1-(4-bromophenyl)-2-[(6-ethoxy-1,3-benzothiazol-2-yl)sulfanyl]ethanone; 2-methyl-N-(3-nitrophenyl)quinoline-8-sulfonamide; N-[2-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]-6-phenylthieno[2,3-d]pyrimidin-4-amine; 3-(thiophen-2-yl)imidazo[1,5-a]pyridine; ethyl 3-[2-(3,4-dimethoxyphenyl)ethyl]-6-methyl-3,4-dihydro-2H-furo[3',2':3,4]naphtho[2,1-e][1,3]oxazine-5-carboxylate; (2E)-1-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-3-(4-fluorophenyl)prop-2-en-1-one; 1-benzyl-4-(naphthalen-2-ylsulfonyl)piperazine; 4-(4-benzylpiperazin-1-yl)-5-(4-chlorophenyl)-6-methylthieno[2,3-d]pyrimidine; 2-{[2-(morpholin-4-yl)-2-oxoethyl]sulfanyl}-3-phenyl-5-(thiophen-2-yl)thieno[2,3-d]pyrimidin-4(3H)-one; ethyl 5'-[(furan-2-ylcarbonyl)amino]-5-methyl-2,3'-bithiophene-4'-carboxylate; 2-{[2-oxo-2-(pyrrolidin-1-yl)ethyl]sulfanyl}-3-phenyl-5-(thiophen-2-yl)thieno[2,3-d]pyrimidin-4(3H)-one; 2-{[5-(1,3-benzodioxol-5-yl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-methoxyphenyl)ethanone; 2-(4-chlorophenyl)-2-oxoethyl 1-[(4-fluorophenyl)sulfonyl]piperidine-4-carboxylate; N-(2,3-dichlorophenyl)quinoline-8-sulfonamide; 1-(2,4-dichlorophenyl)-2-{[4-ethyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 1-(4-fluorophenyl)-4-(naphthalen-2-ylsulfonyl)piperazine; 8-[(4-benzylpiperidin-1-yl)sulfonyl]quinoline; 8-[(4-benzylpiperazin-1-yl)sulfonyl]quinoline; 8-{[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]sulfonyl}quinoline; 1-(4-chlorophenyl)-2-{[4-ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 2-{[4-ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-fluorophenyl)ethanone; 1-(2,4-dichlorophenyl)-2-{[4-ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 1-(2,4-dichlorophenyl)-2-{[4-methyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; [4-(azepan-1-ylsulfonyl)phenyl](3,5-dimethyl-1H-pyrazol-1-yl)methanone; N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide; 3-chloro-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-6-fluoro-1-benzothiophene-2-carboxamide; methyl {[5-{[(2-methylquinolin-8-yl)oxy]methyl}-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetate; 3-chloro-6-fluoro-N-[4-(morpholin-4-yl)phenyl]-1-benzothiophene-2-carboxamide; N-(1,3-benzodioxol-5-yl)-3-(piperidin-1-ylsulfonyl)benzamide; 2-{[5-{[(2-methylquinolin-8-yl)oxy]methyl}-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide; 1,3-benzodioxol-5-ylmethyl 3-(piperidin-1-ylsulfonyl)benzoate; methyl {[5-(3,6-dichloro-1-benzothiophen-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetate; 3-(azepan-1-ylsulfonyl)-N-[2-(morpholin-4-yl)ethyl]benzamide; N-[2-(morpholin-4-yl)ethyl]-3-(piperidin-1-ylsulfonyl)benzamide; dimethyl 5-[(4-methoxybenzoyl)amino]-3-methylthiophene-2,4-dicarboxylate; [4-(2-methoxyphenyl)piperazin-1-yl][4-(piperidin-1-ylsulfonyl)phenyl]methanone; [4-(morpholin-4-ylsulfonyl)phenyl][4-(pyridin-2-yl)piperazin-1-yl]methanone; N-(4-acetylphenyl)-4-(3-chlorophenyl)piperazine-1-carbothioamide; [4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl][4-(pyrrolidin-1-ylsulfonyl)phenyl]methanone; 2-[4-(azepan-1-ylsulfonyl)phenyl]-1,3-benzothiazole; [4-(2-fluorophenyl)piperazin-1-yl][4-(pyrrolidin-1-ylsulfonyl)phenyl]methanone; [4-(4-fluorophenyl)piperazin-1-yl][3-(morpholin-4-ylsulfonyl)phenyl]methanone; 2-({[4-(4-methoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}methyl)-1,3-benzothiazole; 2-{[4-(2,3-dimethylphenyl)-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone; N-[2-(morpholin-4-yl)ethyl]-3-(pyrrolidin-1-ylsulfonyl)benzamide; N-(4-acetylphenyl)-4-(4-fluorophenyl)piperazine-1-carbothioamide; N-(1,3-benzodioxol-5-ylmethyl)-3-(morpholin-4-ylsulfonyl)benzamide; 2-{[5-(3-chloro-1-benzothiophen-2-yl)-4-ethyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-nitrophenyl)ethanone; 2-{[4-ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-nitrophenyl)ethanone; methyl 4-({[4-(4-fluorophenyl)piperazin-1-yl]carbothioyl}amino)benzoate; ethyl 4-[(2-methylquinolin-8-yl)sulfonyl]piperazine-1-carboxylate; 2-({[5-(1,3-benzodioxol-5-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}methyl)-1,3-benzothiazole; ethyl 2-({[4-(4-fluorophenyl)piperazin-1-yl]acetyl}amino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; 4-methyl-N-[2-(morpholin-4-yl)ethyl]-3-(piperidin-1-ylsulfonyl)benzamide; 8-{[4-(4-methoxyphenyl)piperazin-1-yl]sulfonyl}quinoline; 2-{[4-(4-methoxyphenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone; 2-{[5-(3-chloro-1-benzothiophen-2-yl)-4-ethyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone; 1-(2,4-dichlorophenyl)-2-{[4-(prop-2-en-1-yl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 4-{4-(4-methoxyphenyl)-5-[(4-nitrobenzyl)sulfanyl]-4H-1,2,4-triazol-3-yl}pyridine; ethyl 2-{[2-methoxy-5-(pyrrolidin-1-ylsulfonyl)benzoyl]amino}-4,5-dimethylthiophene-3-carboxylate; methyl 4-({[4-(3-chlorophenyl)piperazin-1-yl]carbothioyl}amino)benzoate; N-(1,3-benzodioxol-5-ylmethyl)-3-(piperidin-1-ylsulfonyl)benzamide; 1-(2,4-dichlorophenyl)-2-{[4-phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; (2E)-3-(3,4-dimethoxyphenyl)-N-{5-[(2-oxo-2-phenylethyl)sulfanyl]-1,3,4-thiadiazol-2-yl}prop-2-enamide; 4-{5-[(3,4-dichlorobenzyl)sulfanyl]-4-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl}pyridine; 8-{[4-(2-fluorophenyl)piperazin-1-yl]sulfonyl}-2-methylquinoline; 1-(4-fluorophenyl)-2-({4-phenyl-5-[(quinolin-8-yloxy)methyl]-4H-1,2,4-triazol-3-yl}sulfanyl)ethanone; 2,2'-[(4,4'-diethyl-4H,4'H-3,3'-bi-1,2,4-triazole-5,5'-diyl)disulfanediyl]bis(1-phenylethanone); N-(4-acetylphenyl)-4-(4-methoxyphenyl)piperazine-1-carbothioamide; 2-{[5-(1,3-benzodioxol-5-yl)-4-ethyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-nitrophenyl)ethanone; methyl {[4-(4-methoxyphenyl)-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetate; 1-(4-chlorophenyl)-2-{[4-ethyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; [4-(azepan-1-ylsulfonyl)phenyl][4-(3-chlorophenyl)piperazin-1-yl]methanone; 1,3-benzodioxol-5-ylmethyl 4-(pyrrolidin-1-ylsulfonyl)benzoate; 2-{[5-(1,3-benzodioxol-5-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-chlorophenyl)ethanone; 2-{[5-(1,3-benzodioxol-5-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-fluorophenyl)ethanone; [4-(2-methoxyphenyl)piperazin-1-yl][4-(pyrrolidin-1-ylsulfonyl)phenyl]methanone; [4-(3-chlorophenyl)piperazin-1-yl][4-(morpholin-4-ylsulfonyl)phenyl]methanone; 1-(4-chlorophenyl)-2-{[4-(4-methoxyphenyl)-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 1-(2,4-dichlorophenyl)-2-({4-(prop-2-en-1-yl)-5-[(quinolin-8-yloxy)methyl]-4H-1,2,4-triazol-3-yl}sulfanyl)ethanone; 3-(1,3-benzodioxol-5-yl)-4-phenyl-5-[(2-phenylethyl)sulfanyl]-4H-1,2,4-triazole; N-(1,3-benzothiazol-2-yl)-4-[(4-methylpiperidin-1-yl)sulfonyl]benzamide; 1-(biphenyl-4-yl)-2-{[4-(prop-2-en-1-yl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; (2E)-N-{5-[(2-oxo-2-phenylethyl)sulfanyl]-1,3,4-thiadiazol-2-yl}-3-phenylprop-2-enamide; [4-(azepan-1-ylsulfonyl)phenyl][2-(ethylsulfanyl)-1H-benzimidazol-1-yl]methanone; 4-methyl-3-[(4-nitrobenzyl)sulfanyl]-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazole; N-(1,3-benzodioxol-5-yl)-4-[(4-methylpiperidin-1-yl)sulfonyl]benzamide; 3-[(4-nitrobenzyl)sulfanyl]-4-phenyl-5-(thiophen-2-yl)-4H-1,2,4-triazole; 4-[(4-methylpiperidin-1-yl)sulfonyl]-N-(4-phenyl-1,3-thiazol-2-yl)benzamide; ethyl 2-{[(1,3-benzodioxol-5-ylcarbonyl)carbamothioyl]amino}-4,5-dimethylthiophene-3-carboxylate; N-[4-({[4-(prop-2-en-1-yl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetyl)phenyl]benzenesulfonamide; 2-{[5-(1,3-benzodioxol-5-yl)-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-nitrophenyl)ethanone; 2-{[5-(3-chloro-1-benzothiophen-2-yl)-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-fluorophenyl)ethanone; 8-{[4-(pyridin-2-yl)piperazin-1-yl]sulfonyl}quinoline; 1-(3-nitrophenyl)-2-{[4-(prop-2-en-1-yl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; N-(2,5-dimethoxyphenyl)-4-phenylpiperazine-1-carbothioamide; 2-(4-fluorophenyl)-2-oxoethyl 1-[(4-fluorophenyl)sulfonyl]piperidine-4-carboxylate; 2-(3-nitrophenyl)-2-oxoethyl 1-[(4-fluorophenyl)sulfonyl]piperidine-4-carboxylate; 5-(1,3-benzodioxol-5-ylsulfamoyl)-2-methoxybenzoic acid; 1-(3-nitrophenyl)-2-{[4-phenyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 1-(3-nitrophenyl)-2-{[4-(prop-2-en-1-yl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 1-(4-fluorophenyl)-2-{[4-(prop-2-en-1-yl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 2-{[5-(3-chloro-1-benzothiophen-2-yl)-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-methoxyphenyl)ethanone; (2E)-3-(3,4-dimethoxyphenyl)-N-(4-phenyl-1,3-thiazol-2-yl)prop-2-enamide; 1-(4-methoxyphenyl)-2-{[4-phenyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 2-(2-{[5-(1,3-benzodioxol-5-yl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}ethyl)-1H-isoindole-1,3(2H)-dione; 2-(2-{[4-phenyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethyl)-1H-isoindole-1,3(2H)-dione; 1-(4-chlorophenyl)-2-{[5-(furan-2-yl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 2-(4-nitrophenyl)-2-oxoethyl 2-phenylquinoline-4-carboxylate; (2E)-3-(3,4-dimethoxyphenyl)-N-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]prop-2-enamide; 4-(1,3-benzodioxol-5-ylmethyl)-N-[3-(trifluoromethyl)phenyl]piperazine-1-carbothioamide; 4-(4-fluorophenyl)-N-[3-(trifluoromethyl)phenyl]piperazine-1-carbothioamide; 4-phenyl-N-[3-(trifluoromethyl)phenyl]piperazine-1-carbothioamide; 3,4-dihydroquinolin-1(2H)-yl[4-(morpholin-4-ylsulfonyl)phenyl]methanone; 2-{[5-(furan-2-yl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(3-nitrophenyl)ethanone; 1-(4-fluorophenyl)-2-{[5-(4-methoxyphenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; (2E)-3-[3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)-4,5-dimethoxyphenyl]prop-2-enoic acid; 2-(4-nitrophenyl)-2-oxoethyl 1-(quinolin-8-ylsulfonyl)piperidine-4-carboxylate; 5-{[2-(3,4-dimethoxyphenyl)ethyl]sulfamoyl}-2-methoxybenzoic acid; 2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-1-(4-chlorophenyl)ethanone; 1-(3-nitrophenyl)-2-{[4-phenyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 4-nitrobenzyl 1-(quinolin-8-ylsulfonyl)piperidine-4-carboxylate; (2E)-3-[2-(difluoromethoxy)-5-nitrophenyl]-N-(4-phenyl-1,3-thiazol-2-yl)prop-2-enamide; 1-(4-chlorophenyl)-2-{[4-phenyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 3-[(4-nitrobenzyl)sulfanyl]-4-phenyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazole; 2-(3-nitrophenyl)-2-oxoethyl 1-(quinolin-8-ylsulfonyl)piperidine-4-carboxylate; 4-(1,3-benzodioxol-5-ylmethyl)-N-(4-chloro-2-fluorophenyl)piperazine-1-carbothioamide; (3-chloro-6-methoxy-1-benzothiophen-2-yl)(3,4-dihydroisoquinolin-2(1H)-yl)methanone; ethyl 2-{[4-(piperidin-1-ylsulfonyl)benzoyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; 8-[(4-phenylpiperazin-1-yl)sulfonyl]quinoline; 1-(4-chlorophenyl)-2-[(6-ethoxy-1,3-benzothiazol-2-yl)sulfanyl]ethanone; (2E)-N-[4-(morpholin-4-yl)phenyl]-3-(4-nitrophenyl)prop-2-enamide; 2-(4-chlorophenyl)-2-oxoethyl (1,3-benzothiazol-2-ylsulfanyl)acetate; N-(4-phenyl-1,3-thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide; (2E)-3-(4-fluorophenyl)-1-{4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}prop-2-en-1-one; 1-(4-chlorophenyl)-2-{[4-phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 1-(4-nitrophenyl)-2-{[4-phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 4-{5-[(4-nitrobenzyl)sulfanyl]-4-phenyl-4H-1,2,4-triazol-3-yl}pyridine; 1-(4-chlorophenyl)-2-{[4-phenyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 1-(4-fluorophenyl)-2-{[4-phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 1-(4-methoxyphenyl)-2-{[4-phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 1-(4-fluorophenyl)-2-{[4-phenyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; ethyl 2-({(2E)-3-[4-methoxy-3-(piperidin-1-ylsulfonyl)phenyl]prop-2-enoyl}amino)-4,5-dimethylthiophene-3-carboxylate; 3-[({5-[(E)-2-carboxyethenyl]-2-methoxyphenyl}sulfonyl)amino]benzoic acid; 2-{[5-(1,3-benzodioxol-5-yl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone; 1-(3-nitrophenyl)-2-{[4-phenyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; 2-{[5-(3-chlorophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(3-nitrophenyl)ethanone; N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-4-(piperidin-1-ylsulfonyl)benzamide; N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-4-(morpholin-4-ylsulfonyl)benzamide; 2-{[5-(3-chlorophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone; ethyl 2-({[(2E)-3-(furan-2-yl)prop-2-enoyl]carbamothioyl}amino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; 3-(2-methoxyphenyl)imidazo[1,5-a]pyridine; 3-methylimidazo[1,5-a]pyridine-1-carbaldehyde; 1-(4-chlorophenyl)-2-{[4-(prop-2-en-1-yl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone; (3-chloro-6-methoxy-1-benzothiophen-2-yl)[4-(4-methoxyphenyl)piperazin-1-yl]methanone; 2-{[5-(1,3-benzodioxol-5-yl)-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-fluorophenyl)ethanone; 8-{[4-(2-methoxyphenyl)piperazin-1-yl]sulfonyl}quinoline; ethyl 1-{[2-(benzoylamino)-4,5-dimethylthiophen-3-yl]methyl}piperidine-4-carboxylate; N-(4,5-dimethyl-3-{[4-(pyridin-2-yl)piperazin-1-yl]methyl}thiophen-2-yl)benzamide; N-(3-{[4-(2-fluorophenyl)piperazin-1-yl]methyl}-4,5-dimethylthiophen-2-yl)benzamide; (3-benzyl-5,6-dimethyl-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl)(phenyl)methanone; [5,6-dimethyl-3-(pyridin-3-ylmethyl)-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl](phenyl)methanone; [5,6-dimethyl-3-(pyridin-4-ylmethyl)-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl](phenyl)methanone; [3-(4-methoxybenzyl)-5,6-dimethyl-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl](phenyl)methanone; [3-(furan-2-ylmethyl)-5,6-dimethyl-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl](phenyl)methanone; (3-cyclohexyl-5,6-dimethyl-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl)(phenyl)methanone; [5,6-dimethyl-3-(2-phenylethyl)-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl](phenyl)methanone; {3-[2-(cyclohex-1-en-1-yl)ethyl]-5,6-dimethyl-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl}(phenyl)methanone; {3-[2-(1H-indol-3-yl)ethyl]-5,6-dimethyl-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl}(phenyl)methanone; {3-[3-(1H-imidazol-1-yl)propyl]-5,6-dimethyl-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl}(phenyl)methanone; 1-(2-methoxyphenyl)-4-{[(E)-2-phenylethenyl]sulfonyl}piperazine; 2-{[5-(1,3-benzo

112632-96-9