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DSIP

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  Post Date: May 09,2017
  Expiry Date: May 09,2018
  Detailed Description: Cas No. :62568-57-4 Price:1 USD Metric Tons
DSIP
Basic Info.
Model NO.:CAS: 62568-57-4
CAS:62568-57-4
Mf:C35h48n10o15
MW:848.81
Purity:99.5%
Appearance:Lyophilized Powder
Export Markets:Global
Additional Info.
Trademark:shi jin gu
Packing:According to Every Customers′s Requirements
Standard:Qualified
Origin:China
HS Code:2937290018
Production Capacity:20kg/Month
Product Description
Now I will introduce our DSIP (2mg/vial):
Sequence:r-l-Gly-Gly-Asp-Ala-Ser-Gly-Glu
Specification: 2mg/vial;
CAS:62568-57-4
Formula: C35H48N10O15
Molecular Weight: 848.81
Purity: 99.5%min
Description:
Delta sleep-inducing peptide, abbreviated DSIP, is a neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities.

Delta sleep-inducing peptide was first discovered in 1974 by the Swiss Schoenenberger-Monnier group who isolated it from the cerebral venous blood of rabbits in an induced state of sleep. It was primarily believed to be involved in sleep regulation due to its apparent ability to induce slow-wave sleep in rabbits, but studies on the subject have been contradictory.

DSIP is an amphiphilic peptide of molecular weight 850 daltons with the amino acid motif:
N-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-C

It has been found in both free and bound forms in the hypothalamus, limbic system and pituitary as well as various peripheral organs, tissues and body fluids. In the pituitary it co-localises with many peptide and non-peptide mediators such as corticotropin-like intermediate peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), thyroid-stimulating hormone (TSH) and melanin concentrating hormone (MCH). It is abundant in the gut secretory cells and in the pancreas where it co-localises with glucagon.

In the brain its action may be mediated by NMDA receptors. In another study Delta sleep-inducing peptide stimulated Acetyltransferase activity through α1 receptors in rats.It is unknown where DSIP is synthesized.

Applications:
Delta sleep-inducing peptide, abbreviated DSIP, is a neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities.
Many roles for DSIP have been suggested following research carried out using peptide analogues with a greater molecular stability and through measuring DSIP-like immunological (DSIP-LI) response by injecting DSIP antiserum and antibodies.

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  CAS Registry Number:

62568-57-4

  Synonyms: ;EMIDELTIDE;L-tryptophyl-L-alanylglycylglycyl-L-alpha-aspartyl-L-alanyl-L-serylglycyl-L-glutamic acid;tryptophylalanylglycylglycyl-alpha-aspartylalanylserylglycylglutamic acid;Dsip;
  Molecular Formula: C35H48N10O15
  Molecular Weight: 848.8136
  Molecular Structure: 62568-57-4 trp-ala-gly-gly-asp-ala-ser-gly-glu

  Company: Wuhan Yuancheng Gongchuang Technology Co.Ltd.     [ China ]        
  Contact: Chen Shujie
  Tel: 86-027-50756049
  Fax:
  Email: gjchd004@yuanchengtech.com
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