Anastrozole CAS 120511-73-1 (jerryzhang001@chembj.com)

• Post Date:

  Apr 20,2017

• Expiry Date:

  Apr 20,2018

• Detailed Description:

  Cas No. :120511-73-1 Payment Method: T/T; Western Union; Moneygram and Bitcoin
  Anastrozole CAS 120511-73-1
  
  
  Product Name: Anastrozole
  Synonyms: ICI-D-1033;ARIMIDEX;1-[3,5-DI-(1-METHYL-1-CYANO)-ETHYL]-BENZYL-1,2,4-TRIAZOLE;ANASTRAZOLE;ANASTROZOLE;tetramethyl-5-(1h-1,2,4-triazol-1ylmethyl) 1,3-benzenediacetionitrile;ZD-1033;1,3-benzenediacetonitrile,alpha,alpha,alpha’,alpha’-tetramethyl-5-(1h-1,2,4-t
  CAS: 120511-73-1
  MF: C17H19N5
  MW: 293.37
  Product Categories: Active Pharmaceutical Ingredients;Antineoplastic;All Inhibitors;anti-neoplastic;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Anastrozole;API
  mp 81-82°C
  storage temp. Store at RT
  HS Code 29339980
  Chemical Properties : Crystalline Solid
  Usage : An aromatase inhibitor. Used as an antineoplastic.
  antiseptic, spermaticide
  
  Biological Activity : Potent and highly selective aromatase (CYP19) inhibitor (IC 50 = 15nM) that has no discernible effect on adrenocorticoid hormone synthesis. Reduces plasma estrogen levels and exhibits antitumor activity in vivo . Orally active.
  
  Application:
  The third generation of aromatase inhibitors. For the treatment of the patients with advanced breast cancer in postmenopausal.
  Treatment of breast cancer.
  
  The third generation of aromatase inhibitors. For the treatment of the patients with advanced breast cancer in postmenopausal. Three azole aromatase inhibitors are potent selective, it can inhibit the cytochrome P-450 dependent aromatase thereby blocking the biosynthesis of estrogen and estrogen, the main factors to stimulate the growth of breast cancer cells. The treatment of breast cancer, especially suitable for those who use hormonal adjuvant therapy after relapse after menopause women with advanced breast cancer.
  
  Raw materials : Ethyl acetate-->N,N-Dimethylformamide-->PETROLEUM ETHER-->Sodium hydride -->Carbon tetrachloride-->Iodomethane-->N-Bromosuccinimide-->1,2,4-Triazole-->1,2,4-Triazolylsodium-->5-Methyl-1,3-benzenediacetonitrile

• CAS Registry Number:

  120511-73-1

• Synonyms:

  ;Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetionitrile;ICI-D-1033;Arimidex;1-[3,5-DI-(1-METHYL-1-CYANO)-ETHYL]-BENZYL-1,2,4-TRIAZOLE;ANASTRAZOLE;tetramethyl-5-(1h-1,2,4-triazol-1ylmethyl) 1,3-benzenediacetionitrile;ZD-1033;1,3-benzenediacetonitrile,alpha,alpha,alpha',alpha'-tetramethyl-5-(1h-1,2,4-triazol-1-ylmethyl)-;Anastrozol;Anatrozole;ZD-1033, ICI-D-1033, Arimidex;2-[3-(2-Cyano-2-propyl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropiononitrile;1,3-benzenediacetonitrile, alpha,alpha,alpha',alpha'-tetramethyl- 5-(1h-1,2,4-triazol-1-ylmethyl)- zd;1,3-Benzenediacetonitrile,a,a,a',a'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl);2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)benzene-1,3-diyl]bis(2-methylpropanenitrile);

• Molecular Formula:

  C₁₇H₁₉N₅

• Molecular Weight:

  293.37

• Molecular Structure:

  

• Company:

  Nanjing Bangnuo Biotechnology Co., Ltd.     [ China ]        

• Contact:

  Jerry Zhang

• Tel:

  86-25-52198306

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• Email:

  jerryzhang001@chembj.com