BIBW 2992

• Post Date:

  Jan 18,2016

• Expiry Date:

  Jan 17,2017

• Detailed Description:

  Cas No. :439081-18-2 Quantity: 100Kilograms
  Price:6000 USD Kilograms
  Payment Method: L/C ,T/T.Paypal.Western Union
  
  Product Name: BIBW 2992
  CAS: 439081-18-2
  MF: C24H25ClFN5O3
  MW: 485.944
  EINECS:
  Product Categories: API
  Mol File: 439081-18-2.mol
  BIBW 2992 Chemical Properties
  Density 1.380
  BIBW 2992 Usage And Synthesis
  Usage BIBW2992 (Afatinib, Tomtovok, Tovok) irreversibly inhibits EGFR/HER2 including EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively.
  
  Synonyms:
  BIBW 2992;N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide;Tovok;Tovok, BIBW 2992;BIBW2992 Afatinib;Afatinib (BIBW 2992);ToMtovok;(S,E)-N-(4-(3-chloro-4-fluorophenylaMino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl)-4-(diMethylaMino)but-2-enaMide

• CAS Registry Number:

  439081-18-2

• Synonyms:

  ;BIBW 2992;BIBW-2992;Tovok;2-Butenamide, N-(4-((3-chloro-4-fluorophenyl)amino)-7-(((3S)-tetrahydro-3-furanyl)oxy)-6-quinazolinyl)-4-(dimethylamino)-;(2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl}-4-(dimethylamino)but-2-enamide;Afatinib;(E)-N-(7-((S)-tetrahydrofuran-3-yloxy)-4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide;BIBW2992;(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-dime;

• Molecular Formula:

  C₂₄H₂₅ClFN₅O₃

• Molecular Weight:

  485.9384

• Molecular Structure:

  

• Company:

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