Buy MGF HGH(Human Growth Hormone) 100% Authentic High Quality Factory Price Online
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Post Date:
Apr 21,2015
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Expiry Date:
Apr 20,2016
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Detailed Description:
Quantity: 10,000 Boxes
Specs:2mg/vial.10vials/kit
Price:70-85/box USD Metric Tons
Payment Method: WU, MG
[Introduction of MGF]
Mechano growth factor (MGF) is a novel splice variant of the Insulin-Like Growth Factor-1 (IGF-1), also known as IGF-1 Ec in humans and IGF-1Eb in rodents. It is actually originally called MGF because the RNA form of it is expressed in muscle tissues in response to the overload or/and damage of muscle growth tissue. The C-terminal peptide of the mechano growth factor (MGF) is a crucial region for the alternative splicing of the peptide. The alternative splicing in the MGF is brought about by the shift in the reading frame in which a specific C-terminal sequence (E-domain) is encoded by exon 5 and the first part of the exon 6. Another interesting point in MGF is that, because of the E domain it contains, MGF can act on muscles independently from the rest of the molecule. Furthermore, MGF can elicit very different effects with mGF promoting satellite cells proliferation and IGF-1 inducing differentiation.
The physiological function of MGF was studied using an in vitro cell model. Unlike mature IGF-I, the distinct E domain of MGF inhibits terminal differentiation whilst increasing myoblast proliferation. Blocking the IGF-I receptor with a specific antibody indicated that the function of MGF E domain is mediated via a different receptor. The results provide a basis for localized tissue adaptation and helps explain why loss of muscle mass occurs in the elderly and in dystrophic muscle in which MGF production is markedly affected.
[Delivery and shipping]
·We will ship the goods within 1 working days after payment confirmed.
·We will ship the goods by safe and fast private express and choose the best courier depend on different countries to make sure it`s the safest way for the items.·
As usual you can get the goods within 5-9 business days depends on the courier chosen.
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For further information, you mat contact us freely, we will reply you as soon as possible to fulfill your requirement.
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Company:
Hongkong HW Co,. Ltd.
[ China ]
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Contact:
Alina
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Tel:
85-571-06984000
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Fax:
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Email:
hkhw4@outlook.com
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