China Solithromycin API 760981-83-7

Post Date:
Oct 26,2015
Expiry Date:
Apr 23,2016
Detailed Description:
Cas No. :760981-83-7 Quantity: 1000g
Specs:95%min
Price:1000g USD Metric Tons
Solithromycin is a highly potent next-generation macrolide, the first fluoroketolide, which has potent activity against most macrolide-resistant strains. In vitro and in vivo studies have shown potent activity against S. pneumoniae as well as an extended spectrum of activity against CA-MRSA, enterococci, Mycobacterium avium and in animal models of malaria. It is also active against atypical bacteria, such as Legionella, Chlamydophila, Chlamydia, Mycoplasma and Ureaplasma and against gonococci and other organisms that cause genitourinary tract infections. It is 8-16 times more potent than azithromycin and is active against azithromycin-resistant strains. Its activity against resistant strains is driven by its ability to bind to three sites on the bacterial ribosome, compared to one or two for current macrolides. The binding to three ribosomal sites is expected to limit resistance development.
CAS Registry Number:
760981-83-7
Molecular Formula:
C₄₃H₆₅FN₆O₁₀
Molecular Weight:
845.00900
Molecular Structure:

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