Glyburide

Post Date:
Apr 14,2014
Expiry Date:
Apr 14,2015
Detailed Description:
Cas No. :10238-21-8
Name Glyburide; Glibenclamide
Molecular Formula C23H28ClN3O5S
Molecular Weight 494.00
CAS Registry Number 10238-21-8
EINECS 233-570-6
MSDS Available

White crystalline powder, odorless, tasteless
Practically insoluble in water,Sparingly soluble in methylene chloride,slightly soluble in alcohol and methanol
M.P170～174℃
Have maximum absorption at 274nm ～300nm wavelength, and have minimum absorption at 272nm～278nm wavelength.
Chloride ≤0.2%
Sulphate ≤0.1%w/w
Impurity A≤0.5%
Impurity B≤0.5%
Any other impurity≤0.2%
Total impurities≤0.5%
Loss on drying≤0.5%
Residue on ignition≤0.1%
Heavy metals≤10ppm
Assay (dried base)99.0～101.0%

For the treatment of type II diabetes.
CAS Registry Number:
10238-21-8
Synonyms:
;glybenclamide;glyburide usp;Glibenclamide;Glyburide;5-chloro-n-(2-(4-((((cyclohexylamino)carbonyl)-amino)sulfonyl)phenyl)-ethyl)-2-methoxybenzamide;5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide;5-chloro-2-methoxy-N-[2-[4-(phenylcarbamoylsulfamoyl)phenyl]ethyl]benzamide;5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide;
Molecular Formula:
C₂₃H₂₂ClN₃O₅S
Molecular Weight:
487.9559
Molecular Structure:

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