High Purity Secnidazole for Anti-Amoebic
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Post Date:
Jan 31,2016
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Expiry Date:
Jan 30,2017
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Detailed Description:
High Purity Secnidazole for Anti-Amoebic
Product Description
1. Quick Detail:
Secnidazole
Alias: Alpha, 2-Dimethyl-5-nitro-1H-imidazole-1-ethanol, Flagentyl; PM 185184; RP 14539
CAS Registry Number: 3366-95-8
Molecular formula: C7H11N3O3
Molecular Weight: 185.18
EINECS: 222-134-0
Appearance: White to off-white or yellowish crystalline powder
Assay: 99%
Related Substances: Pharmaceutical Grade
Storage: Shading, confined preservation
Usage: Use as anti-amoebic drugs, anti-drug trichomoniasis
2. Description:
Secnidazole belongs to category of antiprotozoal agents drugs. Secnidazole is a type of potentiate anticoagulant effect of warfarin. Concurrent disulfĂ® Ram may cause antabuse-like effects cimetidine prolongs half-life.
It belongs to 5 nitroimidazole, effective in intestinal ameobiasis, giardiasis, trichomoniasis or bacterial vaginosis with a single once only dose.
Secnidazole is a nitroimidazole anti-infective. Effectiveness in the treatment of dientamoebiasis has been reported. It has also been tested against Atopobium vaginae. This drug is commonly sold as Brand Name Flagentyl.
3. Applications:
Secnidazole has the advantage of being a single dose treatment and in humans treated with a single dose of secnidazole (30 mg/kg), it achieved up to 98% cure. Researchers, in a comparative study between secnidazole and metronidazole found a curative rate of 100% for secnidazole and 96% for metronidazole. However, when metronidazole was used in a single dose, its curative rate was reduced to 36-54%. On the other hand, a single dose of secnidazole reaches the same response achieved with multiple dosage regimens of metronidazole or tinidazole.
Side Effects of Secnidazole: Nausea, epigastric pain, glossitis, fatigue, head ache, loss of appetite, diarrhea stomatitis, urticaria rash & leucopenia.
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[ China ]
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