Levamisole hydrochloride cetirizine 130018-87-0

• Post Date:

  Jan 15,2019

• Expiry Date:

  Jan 15,2020

• Detailed Description:

  Cas No. :130018-87-0 Specification:
  
  Items
  Acceptance criteria
  Results
  Character
  Appearance: White or almost white powder.
  Almost white powder
  Solubility: Slightly soluble in water, freely
  soluble in dilute acetic acid and in methanol,
  slightly soluble in alcohol.
  Complies
  Identification
  A.Specific optical rotation: –30.0º~-33.5º
  (dried substance)
  –33.3º
  B.Infrared absorption spectrophotometry:
  The IR spectrum is consistent with that
  obtained with Levodropropizine CRS.
  Complies
  Tests
  pH
  9.2~10.2
  9.4
  Impurity B and related
  substances
  Impurity B: ≤ 0.5%
  ≤ 0.1%
  Any other impurity: ≤ 0.1 %
  ≤ 0.1%
  Total impurities: ≤ 0.6 %
  ≤ 0.1%
  Impurity C
  ≤ 5 ppm
  ≤ 5ppm
  Enantiomeric purity
  Impurity A: ≤ 2 %
  0.2 %
  Loss on drying
  ≤ 1.0 %.
  ≤ 0.1%
  Sulphated ash
  ≤ 0.2 %
  ≤ 0.1%
  Assay
  98.5% ~ 101.0%(dried substance)
  99.7%
  Conclusion
  The product meets the specification of EP7.0
  

• CAS Registry Number:

  130018-87-0

• Synonyms:

  ;Leocetirizine Hydrochloride;Levocetirizine 2Hcl;Levocetirizine Dihcl;Levocetirizine Hcl;Levocetrizine Dihydrochloride;[2-[4-[(R)-(4-Chlorophenyl)Phenylmethyl]-1-Piperazinyl]Ethoxy]-Acetic Acid Dihydrochloride;Levocetrizinehcl;Levocitirizine Dihydrochloride;Levo Cetirzine Dihydrochloride;Levocitirizine Dihcl;4-{4-[(S)-(4-Chlorophenyl)(Phenyl)Methyl]Piperazin-1-Yl}Butanoic Acid Hydrochloride (1:1);Levocetirizine Hydrochloride;Levocetrizine Hydrochloride;Levocitirizine 2Hcl;

• Molecular Formula:

  C₂₁H₂₆Cl₂N₂O₂

• Molecular Weight:

  409.34934

• Molecular Structure:

  

• Company:

  Wuhan Benjamin Pharmaceutical Chemical Co.,Ltd     [ China ]          

• Contact:

  Miss Wang

• Tel:

  027-50661278

• Fax:

  027-87569548

• Email:

  sales03@benjaminpharmchem.com