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Levothyroxine Sodium

  • Post Date:

    Sep 10,2017
  • Expiry Date:

    Mar 09,2018
  • Detailed Description:

    Cas No. :25416-65-3 Payment Method: T/T, Western Union, MoneyGram
    Basic info:

    Sodium levothyroxine
    CAS: 25416-65-3
    MF: C15H10I4NNaO4
    MW: 798.85
    EINECS: 200-221-4
    Product Categories: Hormone Drugs
    Appearance: White crystals ,crystalline powder
    Assay: 99%
    Specific Rotation: -0.10 o --- +0.10 o
    Residue on ignition: 0.10% max
    Water-insoluble substance: 0.1% max
    Fumaric Acid: 1.0% max
    Maleic Acid: 0.05% max
    Heavy metals(as Pb): 10 ppm max
    Arsenic(As) : 4 ppm max


    Product Description:

    Levothyroxine (INN, USAN) or L-thyroxine is a synthetic thyroid hormone that is chemically identical to thyroxine (T4), which is naturally secreted by the follicular cells of the thyroid gland. It is used to treat thyroid hormone deficiency, and occasionally to prevent the recurrence of thyroid cancer. Like its naturally secreted counterpart, levothyroxine is a chiral compound in the L-form. The related drug dextrothyroxine (D-thyroxine) was used in the past as a treatment for hypercholesterolemia (elevated
    cholesterol levels) but was withdrawn due to cardiac side effects. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

    Levothyroxine (INN, USAN) or L-thyroxine is a synthetic thyroid hormone that is chemically identical to thyroxine (T4), which is naturally secreted by the follicular cells of the thyroid gland. It is used to treat thyroid hormone deficiency, and occasionally to prevent the recurrence of thyroid cancer. Like its naturally secreted counterpart, levothyroxine is a chiral compound in the L-form. The related drug dextrothyroxine (D-thyroxine) was used in the past as a treatment for hypercholesterolemia (elevated
    cholesterol levels) but was withdrawn due to cardiac side effects.

    Levothyroxine is typically used to treat hypothyroidism, and is the treatment of choice for patients with hypothyroidism, who often require lifelong thyroid hormone therapy. It may also be used to treat goiter via its ability to lower thyroid-stimulating hormone (TSH), a hormone that is considered goiter-inducing. Levothyroxine is also used as interventional therapy in patients with nodular thyroid disease or thyroid cancer to suppress thyroid-stimulating hormone (TSH) secretion.


    Applications:

    Levothyroxine is typically used to treat hypothyroidism,and is the treatment of choice for patients with hypothyroidism, who often require lifelong thyroid hormone therapy.It may also be used to treat goiter via its ability to lower thyroid-stimulating hormone (TSH), a hormone that is considered goiter-inducing.Levothyroxine is also used as interventional therapy in patients with nodular thyroid disease or thyroid cancer to suppress thyroid-stimulating hormone (TSH) secretion.
  • CAS Registry Number:

    25416-65-3
  • Synonyms:

    ;levothyroxine;3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-alanine;3,5,3',5'-tetraiodothyronine;beta-[(3,5-diiodo-4-hydroxyphenoxy)-3,5-diiodophenyl]alanine;l-3,5,3',5'-tetraiodothyronine;l-t4;o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-l-tyrosin;o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine;t4(hormone);tetraiodothyronine;O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine;
  • Molecular Formula:

    C15H11I4NO4
  • Molecular Weight:

    776.87
  • Molecular Structure:

    25416-65-3 L-Thyroxine
  • Hazard Symbols:

     Xn:Harmful;
  • Risk Codes:

    R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.;
  • Safety Description:

    S24/25:;
  • Company:

    Guangzhou Kafen Biotech Co.,Ltd     [ China ]        
  • Contact:

    laura Lin
  • Tel:

    +8613332873040
  • Fax:

  • Email:

    laura@rawroid.com
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