Megestrol acetate
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Post Date:
Sep 02,2015
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Expiry Date:
Feb 29,2016
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Detailed Description:
Cas No. :595-33-5
Product Details
Basic Info.
Model NO.:595-33-5
Product Name:Megestrol Acetate
CAS No.:595-33-5
Appearance:Crystalline Solid Powder
Export Markets:Global
Polciy:Re-Shipping Policy
Delivery:3-7 Working Days Door to Door
Additional Info.
Packing:1kg/Aluminum Foil Bag or as Your Requirement
Standard:SGS, ISO9001, KOSHER
Origin:China
HS Code:3001
Production Capacity:1500kg/Month
Product Description
1. Quick Detail:
Megestrol acetate
Megestrol acetate Product Name:Megestrol acetate
Megestrol acetate CAS:595-33-5
Megestrol acetate MF:C24H32O4
MW:384.51
EINECS:209-864-5
mp:214°C
Megestrol acetate refractive index:11°(C=2, CHCl3)
Megestrol acetate Chemical Properties:Crystalline Solid
Megestrol acetate Usage:Progestogen;Progesterone receptor agonist,Orally active progestogen; formerly used in combinations as oral contraceptive,treatment of endometrial hyperplasia
2. Description:
Megestrol acetate (INN, USAN, BAN, JAN) (abbreviated as MGA or MA, and sold mainly under the brand names Megace and Megace ES), also known as 17α-acetoxy-6-dehydro-6-methylprogesterone, is a steroidal progestin and progesteronederivative (specifically, a 17-hydroxylated progesterone) with predominantly progestational and antigonadotropiceffects.
Though sometimes referred to simply as megestrol, it is important to clarify that megestrol acetate is not the same asmegestrol, which is a closely related but different compound.
3.Application:
Megestrol acetate is used mainly as an appetite stimulant in a variety of conditions and as an antineoplastic agent in the treatment of breast, endometrial, and prostate cancers. When given in relatively high doses, it can substantially increase appetite in most individuals, even those with advanced cancer, and is often used to boost appetite and induceweight gain in patients with cancer or HIV/AIDS-associated cachexia. It is also used as a contraceptive in combination with an estrogen at relatively low doses.
In addition to its use in humans, megestrol acetate has been used extensively in veterinary medicine in the treatment of medical conditions in cats and dogs.
Megestrol acetate COA
Test Items Specification Test Results
Appearance White to creamy white crystalline powder White crystalline powder
Identification IR Complies
Completeness of solution Meets the requirements.500mg being Complies
dissolved in 10ml of acetone
Solubility Insoluble in water, sparingly soluble in Complies
alcohol. Slightly soluble in ether and in
fixed oils, soluble in acetone; very soluble
in chloroform.
Melting range 213ºC~220ºC 217ºC
Specific optical rotation +8.8°~ +12.0° +11.6°
Water ≤0.5% 0.1%
Residue roration ≤0.2% 0.06
Heavy metals ≤0.002% Complies
Assay 97.0%~103.0% 99.6%
Residual solvents Methanol≤1000ppm 74ppm
Ethanol≤1000ppm 39ppm
Methylene chloride≤500ppm 28ppm
Tetrahydrofuran≤300ppm ND
Benzene≤2ppm ND
4. Our advantange
Packing
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Quality
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Delivery
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Price
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Payment
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CAS Registry Number:
595-33-5
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Synonyms:
;17-hydroxy-6-methylpregna-4,6-diene-3,20-dione 17-acetate;6-methyl-3,20-dioxopregna-4,6-dien-17-yl acetate;3,20-dioxopregna-4,6-dien-17-yl acetate;
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Molecular Formula:
C23H30O4
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Molecular Weight:
370.4819
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Molecular Structure:
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Hazard Symbols:
Xn:Harmful;
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Risk Codes:
R40:;
R48:;
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Safety Description:
S22:;
S24/25:;
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Company:
Hubei Yuancheng Saichuang Technology Co.,Ltd.
[ China ]
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Contact:
Silvia
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Tel:
027-50756101
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Fax:
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Email:
exo@yccreate.com
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