NMDA CAS No: 6384-92-5

• Post Date:

  Dec 12,2016

• Expiry Date:

  Dec 12,2017

• Detailed Description:

  Payment Method: TT .L/C
  NMDA
  Detailed Information:
  Key words:GS High purity N-Methyl-D-aspartic acid//NMDA//CAS No: 6384-92-5
  
  Name NMDA CAS No 6384-92-5
  Synonym N-Methyl-D-aspartic acid
  N-Methyl-D-aspartate Molecular weight 147.13
  Molecular formular C5H9NO4 Purity 99%min
  EINECS No / Place of origin China
  Mp 188.5C Appearance White crystal powder
  Grade Standard Medical stand application Animal Pharmaceuticals
  /nutrients/foods
  Documents available COA,MSDS,NMR,GC MDL number MFCD00004226
  
  Shelf life 3 Years Storage Keep in N2. Avoid light
  
  Description:
  Appearance White crystal powder Conforms
  Assay 98.0% Min 98.85%
  Specific rotation -28.0C~-30.0C -29.45C
  Melting point 186~192C 188.5C
  Residue on ignition 0.3% Max 0.12%
  Chloride 200ppm Max Conforms
  Heavy metals 20ppm Max Conforms
  
  
  Application:
  1. As a nutritious food additive for animal
  NMDA has a role in the induction of GnRH (Gonadotropin Releasing Hormone) in the hypothalamus, and of LH (Luteinizing Hormone) and PRL (Prolactin) in the pituitary gland.
  2. As a dietary supplement
  3. As a strength agent
  For it is an agonist of the L-glutamate receptor of the NMDA-type,Among the three families of glutamate receptor proteins identified, one is activated by NMDA
  BIOLOGICAL FUNCTION
  NMDA is an excitatory amino acid neurotransmitter, which only binds to the NMDA receptor without effecting other glutamate receptors (such as those for AMPA and kainate). NMDA specifically binds to the NR2 subunits of NMDA receptor, and then stimulates the open of non-specific cation channel which can allow the passage of Ca2+ and Na+ into the cell and K+ out of the cell. Activation of the NMDA receptor is able to produce the excitatory postsynaptic potential (EPSP), and trigger the increase of intracellular Ca2+ content which may further take participating in various signaling pathways. NMDA receptor plays a key role in a wide range of physiological (e.g. long-term potentiation and neuronal plasticity) and pathological processes (e.g. excitotoxicity and epilepsy)
  
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