NSI-189: A Nootropic Antidepressant That Promotes Neurogenesis

• Post Date:

  Jun 08,2017

• Expiry Date:

  Jun 08,2018

• Detailed Description:

  Quantity: 50Kilograms
  Specs:99% Purity
  Price:1 USD Metric Tons
  Payment Method: Western union,T/T,Money gram, Bitcoin
  NSI-189: A Nootropic Antidepressant That Promotes Neurogenesis
  
  
  Purported Benefits
  
  As mentioned above, the potential benefits of NSI-189 are:
  
  Improvement in behavioral responses associated with depression.[12]
  Reversal of hippocampal atrophy.[13]
  May enhance memory and cognition through increase neurogenesis, particularly in depressed subjects.
  Positive effects may persist after treatment ceases
  
  NSI-189 vs Other Antidepressants
  
  What sets NSI-189 apart from other antidepressants already on the market (e.g., SSRIs)?
  
  Like NSI-189, selective serotonin re-uptake inhibitors (SSRIs) also increase hippocampal neurogenesis. In fact, a famous paper published in Nature showed that SSRI-induced neurogenesis is required for the antidepressant effect. Hence, the fact that SSRIs increase serotonin in the synaptic cleft may be a kind of red herring; the "real" mechanism may in fact result from an increase in neuronal proliferation and integration of these nascent neurons into existing circuits.
  
  Neuralstem identified NSI-189 using a novel approach (which is now patented). Instead of screening for drugs that increase synaptic serotonin or other monoamines, they directly screened a library of 10,000 compounds for their ability to increase neuronal proliferation, survival, and differentiation, leading to the discovery of NSI-189.
  

• Company:

  Wuhan Hengwo Scien-Tech Co., Ltd.     [ China ]        

• Contact:

  Kevin

• Tel:

  +86-15372431628

• Fax:

• Email:

  kevin@ycgmp.com