Rosiglitazone

Post Date:
Dec 15,2013
Expiry Date:
Dec 15,2014
Detailed Description:
Cas No. :122320-73-4 Product name：Rosiglitazone
Molecular formular：C18H19N3O3S
Molecular weight：357.43
CAS No.: 122320-73-4
Characteristics：White or off-white crystalline powder
Melting point：153～155℃
Introductions：Rosiglitazone is an antidiabetic drug in the thiazolidinedione class of drugs. It works as an insulin sensitizer, by binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. It is marketed by the pharmaceutical company GlaxoSmithKline (GSK) as a stand-alone drug (Avandia) and in combination with metformin (Avandamet) or withglimepiride (Avandaryl).
Rosiglitazone is a member of the thiazolidinedione class of drugs. Thiazolidinediones act as insulin sensitizers. They reduce glucose, fatty acid, and insulin blood concentrations. They work by binding to the peroxisome proliferator-activated receptors (PPARs)
CAS Registry Number:
122320-73-4
Synonyms:
;5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]-phenyl]methyl]-2,4-thiazolidine-dione;5-(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}benzyl)-1,3-thiazolidine-2,4-dione;5-(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}benzyl)-1,3-thiazolidine-2,4-dione (2Z)-but-2-enedioate;5-(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}benzyl)-1,3-thiazolidine-2,4-dione hydrochloride;
Molecular Formula:
C₁₈H₂₀ClN₃O₃S
Molecular Weight:
393.8877
Molecular Structure:

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