Spironolactone

• Post Date:

  Sep 02,2016

• Expiry Date:

  Sep 02,2017

• Detailed Description:

  Cas No. :52-01-7 Payment Method: T/T,Money Gram,Bitcoin,Western Union
  Spironolactone
  EINECS:200-133-6
  Molecular Formula:C24H32O4S
  CAS Registry Number:52-01-7
  Synonyms:Alderon; 3-(3-Keto-7.alpha.-acetylthio-17.beta.-hydroxy-4-androsten-17.alph a.-yl)propionic acid lactone; Uractone; Spiro(17H-cyclopenta(a)phenauthrene-17,2-(3H)-furan); Xenalon; Pregn-4-ene-21-carboxylic acid,7-(acetylthio)-17-hydroxy-3-oxo-,?- lactone,(7R,17R)-; Aldactone; 17.alpha.-Pregn-4-ene-21-carboxylic acid, 17-hydroxy-7.alpha.-mercapto-3-oxo-, .gamma.-lactone, acetate; Euteberol; Prestwick_449; Pregn-4-ene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy-3-oxo-, gamma-lactone, (7alpha,17alpha)-; Spironolactone A; Urusonin; Verospirone; SC 9420; SC 15983; Spiro(17H-cyclopenta(a)phenanthrene-17,2(5H)-furan), pregn-4-ene-21-carboxylic acid deriv.; Spiro-Tablinen; Spirolang; Spironolactone [BAN:INN:JAN]; 7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,17-beta-carbolactone; 7-alpha-(acetylthio)-17-alpha-hydroxy-3-oxopregn-4-ene-21-carboxylic acid, gamma-lactone (9CI); 496916-40-6; Spironolactonum [INN-Latin]; Aldactone A; Aldactazide (TN); Spiroctan; 3-(3-Oxo-7-alpha-acetylthio-17-beta-hydroxyandrost-4-en-17-beta-yl)propionic acid lactone; 7-(Acetylthio)-17-hydroxy-3-oxopregn-4-ene-21-carboxylic acid gamma-lactone; Pregn-4-ene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy-3-oxo-, g-lactone, (7a,17a)-; Verospiron;
  
  Chemical Properties
  Appearance:White powder.
  Molecular Weight:416.57
  Density:1.24g/cm3
  Boiling Point:597℃ at 760mmHg
  Melting Point:198-207℃
  Flash Point:302.3℃
  Alpha:-37 ° (C=1, CHCL3)
  Storage Temperature:Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.
  Refractive index:-36 ° (C=1, CHCl3)
  Solubility:practically insoluble
  Biological Activity:Competitive mineralocorticoid (aldosterone) receptor antagonist that exhibits antihypertensive activity in vivo . Also displays antiandrogen activity and inhibits steroid hormone biosynthesis.
  Stability:Stable under normal temperatures and pressures.
  Usage:It is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypok.
  

• CAS Registry Number:

  52-01-7

• Synonyms:

  ;7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,17-beta- carbolactone; ;S-(10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-yl) ethanethioate;S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-yl] ethanethioate;S-[(7R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-yl] ethanethioate;17-Hydroxy-7-alpha-mercapto-3-oxo-17-alpha-pregn-4-ene-21-carboxylic acid-gamma-lactone-7-acetate;

• Molecular Formula:

  C₂₄H₃₂O₄S

• Molecular Weight:

  416.5735

• Molecular Structure:

  

• Hazard Symbols:

   T:Toxic;
   Xn:Harmful;
  

• Risk Codes:

  R40:;
  R60:;
  

• Safety Description:

  S53:;
  S22:;
  S36/37/39:;
  S45:;
  

• Company:

  Hubei Saichuang Tech     [ China ]        

• Contact:

  Selina Hu

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  +86-027-50756039

• Fax:

• Email:

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