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Terlipressin Acetate

  • Post Date:

    Jan 13,2013
  • Expiry Date:

    Jan 13,2014
  • Detailed Description:

    Cas No. :14636-12-5 Quantity: 1Kilograms
    Specs:98%
    Molecular Formula:
    C52H74N16O15S2

    Relative Molecular Mass:
    1227.39 g/mol

    CAS-Number:
    14636-12-5


    Long-term Storage:
    -20 ± 5°C


    Sequence:
    H-Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 acetate salt
    (Disulfide bond)

    Fields of Application:

    Acute variceal hemorrhage (esophageal varices)
    Hepatorenal syndrome
    Norepinephrine-resistant septic shock - not yet an approved application

    Active Substance:
    Terlipressin is a synthetic analog of vasopressin and is used as a vasoactive drug in the management of hypotension.
    Terlipressin represents a prodrug, it is converted to (Lys8)- vasopressin (LVP) after removal of the N-terminal triglycine in vivo. Terlipressin has a longer duration of action and a better safety profile than the parent compound LVP
  • CAS Registry Number:

    14636-12-5
  • Synonyms:

    ;n-(n-(n-glycylglycyl)glycyl)-8-l-lysinevasopressin;(2s)-1-[(4s,7s,10s,13s,16s,19s)-19-[[2-[[2-[(2-aminoacetyl)amino]acetyl]amino]acetyl]amino]-13-benzyl-10-(2-carbamoylethyl)-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-n-[(1s)-5-amino-1-(carbamoylmethylcarbamoyl)pentyl]pyrrolidine-2-carboxamide;(2S)-1-{[(4R,7S,10S,13S,16S,19R)-19-{[({[(aminoacetyl)amino]acetyl}amino)acetyl]amino}-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-N-{(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl}pyrrolidine-2-carboxamide (non-preferred name);Terlipressin Acetate;
  • Molecular Formula:

    C52H74N16O15S2
  • Molecular Weight:

    1227.3722
  • Molecular Structure:

    14636-12-5 Terlipressin
  • Company:

    ISPECHEM CO.,LTD     [ China ]        
  • Contact:

    Jeffrey
  • Tel:

    86-755-27802869
  • Fax:

  • Email:

    jeffrey@ispechem.com
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