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Entecavir CAS:142217-69-4

Inquiry
  Post Date: Jan 15,2019
  Expiry Date: Jul 14,2019
  Detailed Description: Cas No. :142217-69-4;1367369-76-3 Inspection Items
Accepted Standard
Results
Appearance
White to off-white powder
Complies
Optical rotation
+24.0°—+28.0°(DMF:MeOH=1:1 c=1%)
+26.8°
Identification
A: By IR, To match with working standard
Complies
B:By HPLC,retain time should match with working standard
Complies
Water
5.8%—6.5%
6.1%
Isomer
Single ≤0.1%
0.02%
Total ≤0.5%
0.02%
Related Substances
Single impurity ≤0.1%
0.02%
Total impurities ≤0.3%
0.03%
Granularity
Particle size
D50≤6.0μm D90≤12.5μm
Complies
Residue on ignition
≤0.1%
0.06%
Heavy metals
£ 20ppm
Complies
Residual solvents
Should be to match with the standard
Complies
Assay
≥99.8%
99.9%
Conclusion Complies to the enterprise standard

  CAS Registry Number:

142217-69-4;1367369-76-3
  Synonyms: ;2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one;2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3,9-dihydro-6H-purin-6-one;2-amino-9-[(3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3,9-dihydro-6H-purin-6-one;2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1,9-dihydro-6H-purin-6-one hydrate (1:1);entecavir Baraclude;
  Molecular Formula: C12H15N5O3
  Molecular Weight: 277.2792
  Molecular Structure: 142217-69-4;1367369-76-3 entecavir

  Company: Wuhan Benjamin Pharmaceutical Chemical Co.,Ltd     [ China ]          
  Contact: Miss Wang
  Tel: 027-50661278
  Fax: 027-87569548
  Email: sales03@benjaminpharmchem.com
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