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Estrogen steroid Estradiol for anti cancer

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  Post Date: Jan 09,2017
  Expiry Date: Jan 09,2018
  Detailed Description: Cas No. :50-28-2 Estradiol

EMAIL: cgf at chembj dot com
Whatsapp: +8615564141272


Synonyms: BETA-ESTRADIOL-16,16,17-D3
CAS: 50-28-2
MF: C18H24O2
MW: 272.38
Content: 99%
Properties: white crystalline powder
Certification: GMP, ISO 9001, USP, BP
Standard: Enterprise standard
Usage:It is used to treat low levels of estrogen caused by certain conditions. It may be used to treat
certain types of prostate cancer (advanced androgen-dependent). It may also be used for other conditions as determined by your doctor.

Estradiol description:

Estradiol, or more precisely, 17β-estradiol, is a human sex hormone and steroid, and the primary female sex hormone. It is named for and is important in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is essential for the development and maintenance of female reproductive tissues[1] but it also has important effects in many other tissues including bone. While estrogen levels in men are lower compared to women, estrogens have essential functions in men as well. Estradiol is found in most vertebrates as well as many crustaceans, insects, fish, and other animal species.

Estradiol is produced especially within the follicles of female ovaries, but also in other endocrine (i.e., hormone-producing) and non-endocrine tissues. Estradiol is biosynthesized fromprogesterone (arrived at in two steps from cholesterol, via intermediate pregnenolone). One principle pathway then converts progesterone to its 17-hydroxy-derivative, and then to androstenedione via sequential cytochrome P450-catalyzed oxidations. Action of aromatase on this dione generates estrone, and action of a dehydrogenase on this gives the title compound, 17β-estradiol.

Applications:

The effects of daily injections of 5 microgram estradiol benzoate (EB) on the patterns of food and ethanol consumption were studied in ovarectomized rats given free access to food, a 10% ethanol solution, and water. EB led to an immediate, but transient, suppression of both food and ethanol intake. The time course and magnitude of these effects were virtually identical. While the decrease in total food intake was achieved by a permanent decrease in the duration of eating bouts, the decline in total ethanol consumption apparently resulted from decreased rates of licking within bouts. Gradual increases in the frequency of eating and ethanol-drinking bouts allowed total food and ethanol intake to return to baseline within three weeks of the first injection. Total water intake rose three-fold during EB administration and this was due to increases in both the duration and frequency of drinking bouts. The similarity in effects induced by EB on the patterns of food and ethanol intake were discussed in terms of ethanol's caloric property.

Advantage

Quality
Our company is a professional production of hormone Steroids and peptides for 12 years,
all of our products have to be tested in professional lab before selling, it must meet the in-house quality control standard. Actual Purity is more than 99%. and we have got very good feedback from our customers, you can trust us

Package
We will use different packaging with different products for different countries , such as food packsges.so on.

Delivery
Package will be shipped with 3 days after payment. We can send it via HKEMS, EUB, DHL .UPS, TNT.FedEx or other method. We have a professional and stable logistics, We will decided to choose which courier depend on Different countries.To find the best way to delivery the goods for you..If the goods were lost or not received for other reasons, please contact me Immediately.We will give you arrange resend

Clearance
Our clearance rate is very high, especially for Brazil, Australia, Canada .Mexico, Chile,and other countries, we have special packaging for better Clearance

  CAS Registry Number:

50-28-2

  Synonyms: ;1,3,5-estratriene-3,17beta-diol;17beta-estradiol;3,17beta-dihydroxy-1,3,5(10)-estratriene; dihydrofolliculin;(8alpha,9beta,13alpha,14beta,17alpha)-estra-1,3,5(10)-triene-3,17-diol;Beta-Estradiol;B-estradiol;17ß-Estradiol;Estradiol;
  Molecular Formula: C18H24O2
  Molecular Weight: 272.382
  Molecular Structure: 50-28-2 β-estradiol
  Hazard Symbols:  T:Toxic;
  Risk Codes: R45:;
  Safety Description: S53:;
S45:;

  Company: Jian Jiage biological technology co, ltd     [ China ]        
  Contact: Lillian
  Tel: +8615564141272
  Fax: 053185826061
  Email: cgf@chembj.com
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