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Levothyroxine Sodium

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  Post Date: Sep 10,2017
  Expiry Date: Mar 09,2018
  Detailed Description: Cas No. :51-48-9;25416-65-3 Payment Method: T/T, Western Union, MoneyGram
Basic info:

Sodium levothyroxine
CAS: 25416-65-3
MF: C15H10I4NNaO4
MW: 798.85
EINECS: 200-221-4
Product Categories: Hormone Drugs
Appearance: White crystals ,crystalline powder
Assay: 99%
Specific Rotation: -0.10 o --- +0.10 o
Residue on ignition: 0.10% max
Water-insoluble substance: 0.1% max
Fumaric Acid: 1.0% max
Maleic Acid: 0.05% max
Heavy metals(as Pb): 10 ppm max
Arsenic(As) : 4 ppm max


Product Description:

Levothyroxine (INN, USAN) or L-thyroxine is a synthetic thyroid hormone that is chemically identical to thyroxine (T4), which is naturally secreted by the follicular cells of the thyroid gland. It is used to treat thyroid hormone deficiency, and occasionally to prevent the recurrence of thyroid cancer. Like its naturally secreted counterpart, levothyroxine is a chiral compound in the L-form. The related drug dextrothyroxine (D-thyroxine) was used in the past as a treatment for hypercholesterolemia (elevated
cholesterol levels) but was withdrawn due to cardiac side effects. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

Levothyroxine (INN, USAN) or L-thyroxine is a synthetic thyroid hormone that is chemically identical to thyroxine (T4), which is naturally secreted by the follicular cells of the thyroid gland. It is used to treat thyroid hormone deficiency, and occasionally to prevent the recurrence of thyroid cancer. Like its naturally secreted counterpart, levothyroxine is a chiral compound in the L-form. The related drug dextrothyroxine (D-thyroxine) was used in the past as a treatment for hypercholesterolemia (elevated
cholesterol levels) but was withdrawn due to cardiac side effects.

Levothyroxine is typically used to treat hypothyroidism, and is the treatment of choice for patients with hypothyroidism, who often require lifelong thyroid hormone therapy. It may also be used to treat goiter via its ability to lower thyroid-stimulating hormone (TSH), a hormone that is considered goiter-inducing. Levothyroxine is also used as interventional therapy in patients with nodular thyroid disease or thyroid cancer to suppress thyroid-stimulating hormone (TSH) secretion.


Applications:

Levothyroxine is typically used to treat hypothyroidism,and is the treatment of choice for patients with hypothyroidism, who often require lifelong thyroid hormone therapy.It may also be used to treat goiter via its ability to lower thyroid-stimulating hormone (TSH), a hormone that is considered goiter-inducing.Levothyroxine is also used as interventional therapy in patients with nodular thyroid disease or thyroid cancer to suppress thyroid-stimulating hormone (TSH) secretion.

  CAS Registry Number:

51-48-9;25416-65-3

  Synonyms: ;levothyroxine;3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-alanine;3,5,3',5'-tetraiodothyronine;beta-[(3,5-diiodo-4-hydroxyphenoxy)-3,5-diiodophenyl]alanine;l-3,5,3',5'-tetraiodothyronine;l-t4;o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-l-tyrosin;o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine;t4(hormone);tetraiodothyronine;O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine;
  Molecular Formula: C15H11I4NO4
  Molecular Weight: 776.87
  Molecular Structure: 51-48-9;25416-65-3 L-Thyroxine
  Hazard Symbols:  Xn:Harmful;
  Risk Codes: R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.;
  Safety Description: S24/25:;

  Company: Guangzhou Kafen Biotech Co.,Ltd     [ China ]        
  Contact: laura Lin
  Tel: +8613332873040
  Fax:
  Email: laura@rawroid.com
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