Oxytocin
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| Post Date: | Dec 18,2018 |
| Expiry Date: | Dec 18,2019 |
| Detailed Description: |
Cas No. :50-56-6
Oxytocin
Detailed Product Description Peptide: Peptide For Bodybuilding Dosage: Can Customise As Require Recipe: Provided For Free To Our Customers Powder Source: Usp Standard Powder Pakage: Disguise Package Or As Require Price List: Welcome Inquiry Effect: Bodybuilding Fitness Shipping: 3-7days Min Order: 10 Vials Vial Size: 3ml Labels: Please Contact For Detail Oxytocin Peptides Steroids Oxytocin 2mg/Vial Freeze-Dried Peptide Oxytocin For Sale Oxytocin is a mammalian hormone that acts primarily as a neuromodulator in the brain. Oxytocin is best known for its roles in sexual reproduction, in particular during and after childbirth. It is released in large amounts after distension of the cervix and uterus during labor, facilitating birth, and after stimulation of the nipples, facilitating breastfeeding. The word oxytocin was derived from the Greek word", meaning quick birth. The oxytocin peptide is synthesized as an inactive precursor protein from the OXT gene. Oxytocin is a peptide of nine amino acids (a nonapeptide). Its systematic name is cysteine-tyrosine-isoleucine-glutamine-asparagine-cysteine-proline-leucine-glycine-amine (cys, tyr, ile,gln,asn,cys, pro, leu, gly - NH2, or CYIQNCPLG-NH2). The cysteine residues form a disulfide bond. Oxytocin has a molecular mass of 1007 daltons. One international unit (IU) of oxytocin is the equivalent of about 2 micrograms of pure peptide. The trust-inducing property of oxytocin might help those who suffer from social anxieties and mood disorders, but with the potential for abuse with confidence tricks and military applications. Oxytocin (Oxt) is a mammalian neurohypophysial hormone. Produced by the hypothalamus and stored and secreted by the posterior pituitary gland, oxytocin acts primarily as a neuromodulator in the brain. Oxytocin plays an important role in the neuroanatomy of intimacy, specifically in sexual reproduction of both sexes, in particular during and after childbirth; its name, meaning "swift childbirth", comes from Greek, oksys "swift" and , tokos "birth." It is released in large amounts after distension of the cervix and uterus during labor, facilitating birth, maternal bonding, and, after stimulation of the nipples, lactation. Both childbirth and milk ejection result from positive feedback mechanisms.. Applications: Oxytocin is used for stimulation of uterus contractions to facilitate parturition, induced abortion, postpartumhemorrhage, fetus membranes retains, and postpartum uterus meromorphosis. 2ml:20 Units, the proposed doses for subcutaneously or intramuscular administration of Oxytocin are 30~100I.U. for horse and cow, 10~50I.U. for caprine and swine, 2~10I.U. for dog. Function & Usage Injected oxytocin analogues are used for labor induction and to support labor in case of difficult parturition. It has largely replaced as the principal agent to increase uterine tone in acute postpartum hemorrhage. Oxytocin is also used in veterinary medicine to facilitate birth and to stimulate milk release. The tocolyticagent atosiban (Tractocile) acts as an antagonist of oxytocin receptors; this drug is registered in many countries to suppress premature labor between 24 and 33 weeks of gestation. It has fewer side effects than drugs previously used for this purpose (ritodrine). Oxytocin and the Gastro Tract Oxytocin is destroyed in the gastrointestinal tract, so must be administered by injection or as nasal spray. It has a half-life of typically about three minutes in the blood, and given intravenously does not enter the brain in significant quantities - it is excluded from the brain by the blood-brain barrier. Evidence in rhesus macaques indicates oxytocin by nasal spray does enter the brain. Oxytocin nasal sprays have been used to stimulate breastfeeding, but the efficacy of this approach is doubtful. Neural Sources of Oxytocin In the hypothalamus, oxytocin is made in magnocellular neurosecretory cells of the supraoptic and paraventricular nuclei, and is stored in Herring bodies at the axon terminals in the posterior pituitary. Oxytocin is also made by some neurons in the paraventricular nucleus that project to other parts of the brain and to the spinal cord.[73] Depending on the species, oxytocin receptor-expressing cells are located in other areas, including the amygdala and bed nucleus of the stria terminalis. In the pituitary gland, oxytocin is packaged in large, dense-core vesicles, where it is bound to neurophysin I. Secretion of oxytocin from the neurosecretory nerve endings is regulated by the electrical activity of the oxytocin cells in the hypothalamus. Non-neural sources of Oxytocin Outside the brain, oxytocin-containing cells have been identified in several diverse tissues, including the corpus luteum, the interstitial cells of Leydig, the retina, the adrenal medulla, the placenta, the thymus and the pancreas. The finding of significant amounts of this classically "neurohypophysial" hormone outside the central nervous system raises many questions regarding its possible importance in these different tissues. The Leydig cells in some species have also been shown to possess the biosynthetic machinery to manufacture testicular oxytocin de novo, to be specific, in rats (which can synthesize vitamin C endogenously), and in guinea pigs, which, like humans, require an exogenous source of vitamin C (ascorbate). |
| CAS Registry Number: | 50-56-6 |
| Synonyms: | ;oxytocin lyophilized;H-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 Disulfide bond;H-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Disulfide bond);oxtocin;(2s)-1-[(4r,7s,10s,13s,16s,19r)-19-amino-13-[(2s)-butan-2-yl]-10-(2-carbamoylethyl)-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-n-[(1s)-1-(carbamoylmethylcarbamoyl)-3-methyl-butyl]pyrrolidine-2-carboxamide;Oxytocin Solution;1-{[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-L-leucylglycinamide;1-{[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-L-leucylglycinamide acetate (1:1); |
| Molecular Formula: | C43H66N12O12S2 |
| Molecular Weight: | 1007.19 |
| Molecular Structure: | 
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| Company: | Koffee Pharm Co., Ltd [ China ] |
| Contact: | Sophia |
| Tel: | +86-21-61729394 |
| Fax: | +86-21-61729394 |
| Email: | sophia.koffeepharm@gmail.com |
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