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Powderful Local Anesthetic Tetracaine Base for Anti-Paining Anesthetic CAS 94-24-6

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  Post Date: Nov 20,2017
  Expiry Date: Nov 20,2018
  Detailed Description: Cas No. :94-24-6 Quantity: 1000Kilograms
Specs:foil bag
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Powderful Local Anesthetic Tetracaine Base for Anti-Paining Anesthetic CAS 94-24-6


Quick Detail
Product name  Tetracaine
Other name Testoviron L-Thyroxine,3,3',5,5'-Tetraiodo-L-thyronine,3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine
CAS register number  94-24-6
Quality Standard USP
Molecular formula C15H24N2O2
Molecular weight 264.3633
Assay 99%min
Appearance White Crystalline Solid
Usage Used for mucosal epidermal anesthesia, nerve tissue anesthesia, epidural anesthesia and Subarachnoid space anesthesia



Description:

Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

(1) In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.

(2) Tetracaine is the T in Tac, a mixture of 5 to 12 per cent tetracaine, 5M(per myriad), a half per mille (0.5‰), or .05 per cent (1 part in 2000) , and 4 or 10 per cent hydrochloride used in ear, nose & throat surgery and in the emergemcy department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive locations.

(3) Tetracaine is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.



Applications:

Tetracaine is used in different parts of the body to cause numbness or loss of feeling in some patients before having a medical test or procedure.


COA:

Test Items Specification Test Results
Appearance White crystals or a white crystalline powder Conform
Identification A\B\E. It appears positive reaction
Melting point 154degree~158degree 154degree~157degree
Acidity PH 5.0~6.5 PH=5.9
Appearance of solution Clear and colourless Conform
Loss on drying ≤0.5% 0.07%
Heavy metals ≤0.0005% Conform
Related substances ≤0.05% Conform
Sulphated ash ≤0.1% 0.05%
Assay ( on dry basis ) 99.0-101.0% 99.87%
Conclusion Conform to BP2005



How it works:

Topical anesthetics stabilize the neuronal membrane and prevent the initiation and transmission of nerve impulses, thereby effecting local anesthesia. The onset of anesthesia usually begins within 30 seconds and lasts a relatively short period of time.


Our advantages:

1, High quality with competitive price:
1) Standard:BP/USP/EP/Enterprise standard
2) All Purity≥99%
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  CAS Registry Number:

94-24-6

  Synonyms: ;tetracaine usp;tetracaine free base;Tetracaine Base;amethocaine;Dimethylaminoethylnbutylaminobenzoate;Tetracaine;2-(dimethylamino)ethyl 4-(butylamino)benzoate;
  Molecular Formula: C15H24N2O2
  Molecular Weight: 264.3633
  Molecular Structure: 94-24-6 2-(Dimethylamino)ethyl 4-(n-butylamino)benzoate
  Hazard Symbols:  Xn:Harmful;
  Risk Codes: R22:;
R40:;
R42/43:;
  Safety Description: S22:;
S36/37:;

  Company: Hengyang Desen Biotechnology Co., Ltd.     [ China ]        
  Contact: Koala
  Tel: +86-073-48164621
  Fax: 027-88608190-722
  Email: koala@desen-nutrition.com
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