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Sorafenib tosylate

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  Post Date: Aug 02,2016
  Expiry Date: Aug 02,2017
  Detailed Description: Cas No. :475207-59-1;4750207-59-1 Price:1 USD Kilograms
Payment Method: T/T;MONEYGRAM;WESTERNUNION
Sorafenib tosylate
Chemical Name: 4 - {4 [3 - (4-chloro-3-trifluoromethyl-phenyl) ureide] phenoxy} pyridine-2-carboxamide p-toluenesulfonate
Product Alias: toluenesulfonic sorafenib mesylate Sorafenib Sorafenib p-toluenesulfonic
English name: Sorafenib tosylate
English Synonyms: Sorafenib (Nexavar)
CAS: 475207-59-1
Keywords: Sorafenib tosylate, sorafenib tosylate, mesylate Sorafenib, 475207-59-1
Molecular formula: C21H16ClF3N4O3.C7H8SO3
Molecular Weight: 637.03
Appearance: yellow or white crystalline powder
Melting point: 225-235 ℃
Loss on drying: Less than 0.5%
Heavy metals: Less than 10ppm
Total impurities: less than 1.0%
Content: 99%
Packing: 1kg / aluminum foil bag
Uses: toluenesulfonic Sorafenib is a novel multi-target anticancer drugs, can act simultaneously on tumor cells and tumor blood vessels. It has a dual anti-tumor effects: either by blocking the RAF / MEK / ERK-mediated cell signaling

Pathway directly inhibit the proliferation of tumor cells, but also by inhibiting VEGF and platelet-derived
Health growth factor (PDGF) receptors and block the formation of tumor angiogenesis, indirectly inhibit the growth of tumor cells.

  CAS Registry Number:

475207-59-1;4750207-59-1

  Synonyms: ;SORAFENIB-D3;4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide monomethanesulfonate;N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[4-[2-(N-methylcarbamoyl)-4-pyridyloxy]phenyl]urea Tolsylate;Sorafenib TsOH salt;
  Molecular Formula: C21H16ClF3N4O3·C7H8SO
  Molecular Weight: 637.03
  Molecular Structure: 475207-59-1;4750207-59-1 Sorafenib tosylate

  Company: Wuhan Yuancheng Gongchuang Technology Co.Ltd.     [ China ]        
  Contact: jorcelyn
  Tel: 86-027-50756069
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