Package: As customer request

Uses : It inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent.

Molecular Structure:

Product description: Product Name: Regorafenib Product Name: Regorafenib Synonyms: Regorafenib - BAY 73-4506 | Stivarga;Regorafenib(W.S);Regorafenib;BAY 73-4506;4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide CAS: 755037-03-7 MF: C21H15ClF4N4O3 MW: 482.8154128 EINECS: 815-051-1 Melting point: 206.0 to 210.0 °C form: White powder. Uses: 1.It inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent. 2.BAY 73-4506 (Regorafenib) is a multikinase inhibitor with IC50 of 17, 40 and 69 nM c-KIT, VEGFR2, B-Raf. 3.Regorafenib (BAY 73-4506) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively