RenSin Chemicals Limited

Doxycycline hyclate

• Category :

  Pharmaceuticals and Biochemicals

• Synonyms :

  Doxycycline Hydrochloride Anhydrous;Doxycycline Hydrochloride;(4s,4ar,5s,5ar,6r,12as)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide hydrochloride;(1S,3Z,4aS,11R,11aR,12S,12aR)-3-[amino(hydroxy)methylidene]-4a,6,7,12-tetrahydroxy-N,N,11-trimethyl-2,4,5-trioxo-1,2,3,4,4a,5,11,11a,12,12a-decahydrotetracen-1-aminium chloride;(2Z,4S,4aR,5S,5aR,6R)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride;4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide;Doxycycline Hydrate;4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,5,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-2-Na;(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide-ethanol hydrochloride hydrate (2:1:2:1);4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide-ethanol (2:1) dihydrochloride hydrate;(2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione - ethanol (2:1) dihydrochloride hydrate;(2E,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione - ethanol (2:1) dihydrochloride hydrate;Doxycycline Hyclate;Doxycycline hyclate COS;Doxycycline Hydrochlocide;Doxycycline Hydrochloride Hemiethanolate Hemihydrate;Doxycycline Hyclate Monohydrate;

• CAS NO :

  24390-14-5

• EC NO :

  234-198-7

• Molecular Formula :

  C₂₂H₂₅ClN₂O₈

• Molecular Weight :

  480.8955

• Main Specifications :

  BP/EP

• InChI :

  InChI=1/C22H24N2O8.ClH/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;/h4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31);1H/t7-,10+,14+,15-,17-,22-;/m0./s1

• Packing :

  25KG/DRUM

• Product description :

  　　

  APPEARANCE	YELLOW CRYSTALLINE POWDER
  IDENTIICATION	A.TR OF HPLC TEST
  	B.SULPHURIC ACID YELLOW COLOUR REACTION
  	C. CHLORIDE'S REACTION
  PH	2.0~3.0
  SPECIFIC OPTICAL ROTATION	-105°TO -120°, CALCULATED ON THE ANHYDROUS ETHANOL-FREE SUBSTANCE
  SPECIFIC ABSORBANCE	300~335 AT 349 NM, CALCULATED ON THE ANHYDROUS, ETHANOL-FREE SUBSTANCE
  LIGHT - ABSORBING IMPURITIES	NOT MORE THAN 0.07 AT 490 NM, CALCULATED ON THE ANHYDROUS, ETHANOL-FREE SUBSTANCE
  RELATED SUBSTANCES
  METACYCLINE	NOT MORE THAN 2.0%
  6-EPIDOXYCYCLINE	NOT MORE THAN 2.0%
  ANY INDIVIDUAL IMPURITIES	NOT MORE THAN 0.5%
  DISREGARD LIMIT	NOT MORE THAN 0.1%
  ETHANOL	4.3 ~ 6.0%
  HEAVY METALS	≤50PPM
  WATER	1.4~2.8%
  SULPHATED ASH	NOT MORE THAN 0.4%
  ASSAY	95.0%~102.0% (C22H25CIN2O8) CALCULATED ON THE ANHYDROUS, ETHANOL-FREE SUBSTANCE

• Uses :

  broad-spectrum antibiotic

• Molecular Structure :