Hubei widely chemical technology Co., Ltd

Pazopanib

• Category :

  Pharmaceuticals and Biochemicals

• Synonyms :

  5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide;5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl}amino)-2-methylbenzenesulfonamide;5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl}amino)-2-methylbenzenesulfonamide hydrochloride (1:1);

• CAS NO :

  444731-52-6

• EC NO :

• Molecular Formula :

  C₂₁H₂₄ClN₇O₂S

• Molecular Weight :

  473.979

• Main Specifications :

  99.0%

• InChI :

  InChI=1/C21H23N7O2S.ClH/c1-13-5-6-15(11-19(13)31(22,29)30)24-21-23-10-9-20(25-21)27(3)16-7-8-17-14(2)28(4)26-18(17)12-16;/h5-12H,1-4H3,(H2,22,29,30)(H,23,24,25);1H

• Packing :

  Aluminum bag

• Product description :

  Product Name: Pazopanib                        CAS NO.: 444731-52-6

  Synonyms: 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide;GW 786034;Benzenesulfonamide,5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-;Votrient;

  Assay: >99.0%

  
   
  Molecular Formula: C21H23N7O2S           

  Molecular Weight: 437.52
   
  Boiling Point:728.814 °C at 760 mmHg      

   Flash Point: 394.572 °C

  
   
  Appearance: White or off white crystal powder
   
  Assay: >99.0%
   
  Package: Aluminum bag
   
  Storage: Room temperature
   
  Application: Pazopanib, with its trade name of Votrient, is one kind of potent and selective multi-targeted receptor tyrosine kinase inhibitor of VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-a/β, and c-kit that blocks tumor growth and inhibits angiogenesis. For being one oral angiogenesis inhibitor targeting VEGFR and PDGFR, Pazopanib has been approved for renal cell carcinoma and soft tissue sarcoma. What's more, Pazopanib may also be active in ovarian cancer, and pazopanib also appears effective in the treatment of non-small cell lung carcinoma.

  
   
  Hubei Widely Chemical Technology Co., Ltd. is a professional production and sales of bulk drugs intermediates GMP factory , welcome to inquire pharmaceutical raw materials prices , quality standards and other informations, hope to establish long-term business relationship with you !

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• Molecular Structure :