ER Pharmatech Co.,LTD

AZD9291

• Category :

  Pharmaceuticals and Biochemicals

• Synonyms :

  Mereletinib;AZD9291;Osimertinib;N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide;

• CAS NO :

  1421373-65-0

• EC NO :

• Molecular Formula :

  C₂₈H₃₃N₇O₂

• Molecular Weight :

  499.60700

• Main Specifications :

  99%

• Packing :

  As customer request

• Product description :

  Product Name: AZD-9291 Synonyms: Mereletinib(AZD-9291,Osimertinib);AZD9291 (free base);Osimertinib (AZD-9291);ZAD9291;AZD9291, Osimertinib;AZD9291 Base;Osimertinib Base;N-(2-{[2-(Dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin CAS: 1421373-65-0 MF: C28H33N7O2 MW: 499.61 Uses: AZD-9291 (Osimertinib) is a oral, third generation, small-molecule epidermal growth factor receptor (EGFR) inhibitor and antineoplastic agent. In addition, it is a Cytochrome P450 3A inhibitor, and Cytochrome P450 3A4 Inducer, and Cytochrome P450 1A2 Inducer, and Breast Cancer Resistance Protein Inhibitor. It is used for the treatment of advanced non-small cell lung cancer (NSCLC) where mutant EGFR form (such as T790M) is often presented. Through suppressing the EGFR-mediated signalling, it cause cell death and inhibit tumour growth in related cancer cells.

• Uses :

  AZD-9291 (Osimertinib) is a oral, third generation, small-molecule epidermal growth factor receptor (EGFR) inhibitor and antineoplastic agent. In addition, it is a Cytochrome P450 3A inhibitor, and Cytochrome P450 3A4 Inducer, and Cytochrome P450 1A2 Indu

• Molecular Structure :