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99% Injectable Polypeptide Hormones Bivalirudin Trifluoroacetate CAS 128270-60-0 Bivalirudin
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| Post Date: | Jan 20,2017 |
| Expiry Date: | Jul 19,2017 |
| Detailed Description: |
Cas No. :128270-60-0
Quantity: 1000Kilograms Specs:99% Price:1 USD Kilograms Payment Method: Within 24 hours after we confirm the payment 99% Injectable Polypeptide Hormones Bivalirudin Trifluoroacetate CAS 128270-60-0 Bivalirudin Any problems, please feel free to contact me: Email:jasmine@ycgmp.com whatsapp:+8618872220697 Basic Info: Product Name:Bivalirudin Trifluoroacetate Sequence :D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH Cas No:128270-60-0 Molecular Formula :C98H138N24O33 Molecular Weight :2180.33 Purity (HPLC):98.0%min. Appearance: White Powder Single Impurity (HPLC):1.0%max Amino Acid Composition:±10% of theoretical Peptide Content (N%):≥80.0% Water Content (Karl Fischer):≤8.0% TrifluoroAcetate Content(HPIC):≤12.0% MS (ESI):Consistent Mass Balance:95.0~105.0% Description: Bivalirudin (Angiomax or Angiox, manufactured by The Medicines Company) is a specific and reversible direct thrombin inhibitor (DTI). Bivalirudin is a DTI that overcomes many limitations seen with indirect thrombin inhibitors, such as heparin. Bivalirudin is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin. It inhibits both circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation. Bivalirudin has a quick onset of action and a short half-life. It does not bind to plasma proteins (other than thrombin) or to red blood cells. Therefore it has a predictable antithrombotic response. There is no risk for Heparin Induced Thrombocytopenia/Heparin Induced Thrombosis-Thrombocytopenia Syndrome (HIT/HITTS). It does not require a binding cofactor such as antithrombin and does not activate platelets. These characteristics make bivalirudin an ideal alternative to heparin. Bivalirudin clinical studies demonstrated consistent positive outcomes in patients with stable angina, unstable angina (UA), non-ST segment elevation myocardial infarction (NSTEMI), and ST-segment elevation myocardial infarction (STEMI) undergoing PCI in 7 major randomized trials. Application: Bivalirudin is indicated for use as an anticoagulant in patients with unstable angina undergoing percutaneous transluminal coronary angioplasty (PTCA). Bivalirudin with provisional use of glycoprotein IIb/IIIa inhibitor (GPI) is indicated for use as an anticoagulant in patients undergoing percutaneous coronary intervention (PCI). Bivalirudin is indicated for patients with, or at risk of HIT/HITTS undergoing PCI. Bivalirudin is intended for use with aspirin and has been studied only in patients receiving concomitant aspirin. |
| CAS Registry Number: | 128270-60-0 |
| Synonyms: | ;L-leucine, D-phenylalanyl-L-prolyl-L-arginyl-L-prolylglycylglycylglycylglycyl-L-asparaginylglycyl-L-alpha-aspartyl-L-phenylalanyl-L-alpha-glutamyl-L-alpha-glutamyl-L-isoleucyl-L-prolyl-L-alpha-glutamyl-L-alpha-glutamyl-L-tyrosyl-;D-phenylalanyl-L-prolyl-L-arginyl-L-prolylglycylglycylglycylglycyl-L-asparaginylglycyl-L-alpha-aspartyl-L-phenylalanyl-L-alpha-glutamyl-L-alpha-glutamyl-L-isoleucyl-L-prolyl-L-alpha-glutamyl-L-alpha-glutamyl-L-tyrosyl-L-leucine;Bivalirudin,TFA; |
| Molecular Formula: | C98H138N24O33 |
| Molecular Weight: | 2180.2853 |
| Molecular Structure: | 
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| Company: | Wuhan Yuancheng Gongchuang Technology Co., Ltd [ China ] |
| Contact: | Ann |
| Tel: | 8618872220697 |
| Fax: | 8618872220697 |
| Email: | jasmine@ycgmp.com |
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