Benazepril HCL
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| Post Date: | Jun 06,2020 |
| Expiry Date: | Jun 06,2021 |
| Detailed Description: |
Cas No. :86541-74-4
Quantity: 1Metric Tons Specs:99%min Benazepril hydrochloride Basic information Product Name: Benazepril hydrochloride Synonyms: 1h-1-benzazepine-1-aceticacid,2,3,4,5-tetrahydro-3-((1-(ethoxycarbonyl)-3-phe;cgs14824a;monohydrochloride,(s-(r*,r*))-nylpropyl)amino)-2-oxo;BenazeprilHclC24H28N205.HC1;1H-1-Benzazepine-1-acetic acid, 3-(1S)-1-(ethoxycarbonyl)-3-phenylpropylamino-2,3,4,5-tetrahydro-2-oxo-, monohydrochloride, (3S)-;1H-1-Benzazepine-1-acetic acid, 3-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-, monohydrochloride, [S-(R*,R*)]-;CGS 14824A HCl;Lotensin CAS: 86541-74-4 MF: C24H29ClN2O5 MW: 460.95 EINECS: 630-414-2 Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Amines;Aromatics;Heterocycles;API;SONATA Mol File: 86541-74-4.mol Benazepril hydrochloride Chemical Properties Melting point 188-190°C alpha D -141.0° (c = 0.9 in ethanol) storage temp. Desiccate at +4°C solubility DMSO: ~34 mg/mL, soluble form solid color white Merck 14,1031 InChIKey VPSRQEHTHIMDQM-FKLPMGAJSA-N CAS DataBase Reference 86541-74-4(CAS DataBase Reference )Safety Information Safety Statements 22-24/25 RIDADR 3077 WGK Germany 2 RTECS CX7065000 HS Code 29337900 Hazardous Substances Data 86541-74-4(Hazardous Substances Data) MSDS Information Benazepril hydrochloride Usage And Synthesis Description Benazepril hydrochloride, a prodrug of benazeprilat, is a long-acting angiotensionconverting enzyme (ACE) inhibitor useful in the treatment of essential hypertension. In healthy humans, it was well tolerated and showed no phmacokinetic interactions with furosemide, hydrochlorothiazide, chlorthalidone, digoxin, cimetidine, atenolol, or naproxen. Benazepril hydrochloride is under investigation as a cardiostirnulant. Chemical Properties Crystalline Solid Originator Ciba-Geigy (Switzerland) Uses sedative, hypnotic Uses Used as an antihypertensive; angiotensin converting enzyme inhibitor. Definition ChEBI: A hydrochloride salt resulting from the reaction of benazepril with 1 mol eq. of hydrogen chloride. It is used as a prodrug for angiotensin-converting enzyme inhibitor benazeprilat in the treatment of hypertension and heart failure. Brand name Lotensin (Novartis);Cibacen. Biological Activity Non-peptide angiotensin-converting enzyme (ACE) inhibitor. Reduces blood pressure and myocardial hypertrophy in spontaneous hypertensive rats. |
| CAS Registry Number: | 86541-74-4 |
| Synonyms: | ;benazepril hydrochloride;[(3S)-3-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid hydrochloride;[(3R)-3-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid hydrochloride (1:1); |
| Molecular Formula: | C24H29ClN2O5 |
| Molecular Weight: | 460.95046 |
| Molecular Structure: | 
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| Company: | shanghai missyou chemical co.,ltd. |
| Contact: | eileen zhang |
| Tel: | +86-18101936766 |
| Fax: | 021-58583907 |
| Email: | eileen@shmychem.com |
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