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Cabergoline

Inquiry
  Post Date: Mar 01,2015
  Expiry Date: Feb 29,2016
  Detailed Description: Cas No. :81409-90-7 Quantity: 1Kilograms
Specs:99%
Payment Method: T/T, Western Union, Moneygram
High Quality and Purity 99% Cabergoline for Curing Hormone Imbalance

1.Quick Details:

Product name: Cabergoline
Synonyms: 6-Allyl-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)ergoline-8-carboxamide
Assay: 98.5-102.0%
CAS: 281409-90-7
Molecular formula: C26H37N5O2
Molecular weight: 451.60
Packing: Standard
Package: 1g/foil bag
Storage and Transport conditions Sealed in shade ( +2-+8 °C)
Usage: Treatment of hyperprolactinemia, either idiopathic or due to pituitary adenomas. Investigational: Shrink tumors in clients with microprolactinoma or macroprolactinoma. Parkinson's disease. Normalize androgen levels and improve menstrual cyclicity in polycystic ovary syndrome.

2. Product Description:

Cabergoline was first synthesized by scientists working for the Italian drug company Farmitalia-Carlo Erba SpA in Milan in 1981/82,[2] who were experimenting with semisynthetic derivatives of the ergot alkaloids.

Cabergoline is a long-acting dopamine D2 receptor agonist and in vitro rat studies show a direct inhibitory effect on the prolactin secretion in the pituitary's lactotroph cells. Cabergoline decreased serum prolactin levels in reserpinized rats.
Receptor binding studies indicate a low affinity for dopamine D1 receptors, α1-adrenergic receptors, and α2-adrenergic receptors.

  CAS Registry Number:

81409-90-7

  Synonyms: ;6-allyl-n-[3-(dimethylamino)propyl]-n-(ethylcarbamoyl)ergoline-8-carboxamide;(8-beta)-(2-propenyl);n-(3-(dimethylamino)propyl)-n-((ethylamino)carbonyl)-6-ergoline-8-carboxamid;FCE-21336,Cabaser,Dostinex;(8b)-N-[3-(Dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propen-1-yl)- ergoline-8-carboxamide;Cabaser;Dostine;(8beta)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-6-(prop-2-en-1-yl)ergoline-8-carboxamide;(8β,10ξ)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-6-prop-2-en-1-ylergoline-8-carboxamide;
  Molecular Formula: C26H37N5O2
  Molecular Weight: 451.6043
  Molecular Structure: 81409-90-7 Cabergoline

  Company: Wuhan Hezhong Bio-Chemical Manufacture Co., Ltd     [ China ]        
  Contact: Vicky Huang
  Tel: 86-027-50755980
  Fax: 86-027-88048077
  Email: vicky@chembj.com
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