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Coluracetam powder

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  Post Date: May 05,2016
  Expiry Date: May 05,2017
  Detailed Description: Cas No. :135463-81-9 Quantity: 1Kilograms
Specs:Powder 99.5%
Price:1 USD Kilograms
Payment Method: T/T,western union
Product Name Coluracetam
CAS No. 135463-81-9
Formula C19H23N3O3
Appearance White powder
Purity 99.5%
Package 1Kg/bag
Description Coluracetam (BCI-540) is a nootropic drug of the racetam family.Coluracetam (formerly known as MKC-231) was initially developed and tested by the Mitsubishi Tanabe Pharma Corporation for Alzheimer's disease. After the drug failed to reach endpoints in its clinical trials it was in-licensed by BrainCells Inc for investigations into major depression disorder (MDD), after being awarded a "Qualifying Therapeutic Discovery Program Grant" by the state of California.Findings from its Phase 2a clinical trials have suggested that it would be an ideal medication for co-morbid MDD with generalized anxiety disorder (GAD).BrainCells Inc is currently out-licensing the drug for this purpose.It may also have potential use in prevention and treatment of ischemic retinopathy and retinal and optic nerve injury.
Coluracetam enhances high-affinity choline uptake (HACU) which is the rate-limiting step of acetylcholine (ACh) synthesis, and is the only known choline uptake enhancer to currently exist. Studies have shown Coluracetam to improve learning impairment on a single oral dose given to rats which have been exposed to cholinergic neurotoxins. Subsequent studies have shown that it may induce long-lasting procognitive effects by changing the choline transporter regulation system.

  CAS Registry Number:

135463-81-9

  Synonyms: N-(2,3-Dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide
  Molecular Formula: C19H23N3O3
  Molecular Weight: 341.4042
  Molecular Structure: 135463-81-9 Coluracetam

  Company: Health Powder Inc.     [ China ]        
  Contact: David Lu
  Tel: +86-27-86535669
  Fax:
  Email: export@healthpowder.cn
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