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Dapoxetine hydrochloride

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  Post Date: Dec 10,2016
  Expiry Date: Jun 08,2017
  Detailed Description: Cas No. :129938-20-1 Product Name: Dapoxetine
CAS No.: 119356-77-3
M. F.: C21H23NO
M. W.: 305.4134
Assay: 98%
Packing: Foil bag
Appearance: White crystalline powder

Applications:

Treat male premature ejaculation and erectile dysfunction.
Because lack of specific approval treatment for PE in the US and some other countries, other SSRIs such as fluoxetine, paroxetine, sertraline, fluvoxamine, and citalopram have been used as off label drugs to treat PE. Waldinger's meta analysis shows that the use of these conventional antidepressants increasing IELT from two to ninefold above base line in comparison of three to eightfold when dapoxetine is used. However, these SSRIs must be taken daily in order to achieve meaningful efficacy, and the long half-life increases the risk of the drug accumulation and as a consequence increased of adverse effects such as decreasing sexual libido and causing erectile dysfunction. Dapoxetine, on the other hand, is a fast-acting SSRI. It is rapidly absorbed and eliminated from the body within a few hours. This favorable pharmacokinetics minimizes the risk of the drug's accumulation in the body, and therefore reducing side effects.

  CAS Registry Number:

129938-20-1

  Synonyms: ;DAPOXETINE HCL;Rimonabant 75000;LY-21044;((S)-(+)-N,N-Dimethyl-1-phenyl-3-(1-naphthalenyloxy)propanamine hydrochloride);(S-(+)-N,N-dimethyl-a-[2-(naphthalenyloxy)ethyl] benzenemethanamine hydrochloride;(1S)-N,N-Dimethyl-3-naphthalen-1-yloxy-1-phenyl-propan-1-amine hydrochloride;(S)-n,n-dimethyl-3-(naphthalene-1-yloxy)-1-phenylpropan-1-amine hydrochloride;(S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine hydrochloride;(S-(+)-N,N-Dimethyl-a-[2-(naphthalenyloxy)ethyl]benzenemethanamine hydrochloride;N,N-dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine hydrochloride (1:1);DL-Dapoxteine HCL;Hydrochloric acid Dapoxetine;S-Dapoxetine hydrochloride;D-Dapoxetine HCL;D-Dapoxetine Hydrochloride;
  Molecular Formula: C21H24ClNO
  Molecular Weight: 341.8744
  Molecular Structure: 129938-20-1 Dapoxetine hydrochloride

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