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Dexamethasone-21-Acetate

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  Post Date: Sep 12,2015
  Expiry Date: Sep 11,2016
  Detailed Description: Cas No. :1177-87-3 Quantity: 2000Kilograms
Specs:ISO
Price:1 USD Kilograms
Payment Method: Western Union, MoneyGram, T/T
Dexamethasone-21-Acetate
Synonyms:DEXAMETHASON ACETATE;dexamethasone-17-acetate;DEXAMETHASONE 21-ACETATE
CAS
1177-87-3
storage temp.2-8°C
Molecular formula: C24H31FO6
EINECS:214-646-8
Quality Standards: CP2005/USP/BP/EP
Appearance: White crystalline powder
Assay:99.2%
Product Categories:steriods
Packing: 5KG/TIN,2TIN/CTN
Unit: KG
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Usage:Protected Dexamethasone, a glucocorticoid anti-inflammatory agent.


Product Details:Place of Origin: China
Brand Name: Yuancheng
Certification: ISO9001
Model Number: 1177-87-3
Payment & Shipping Terms:Minimum Order Quantity: 100g
Price: 1800USD~2900USD
Packaging Details: 1kg/aluminium foil bag or as required
Delivery Time: Within 24 hours after receiving the payment
Payment Terms: Western Union, MoneyGram, T/T
Supply Ability: 200kg/month
Applications:

Dexamethasone-17-acetate, a corticosteroid, is similar to a natural hormone produced by your adrenal glands. It often is used to replace this chemical when your body does not make enough of it. It relieves inflammation (swelling, heat, redness, and pain) and is used to treat certain forms of arthritis; skin, blood, kidney, eye, thyroid, and intestinal disorders (e.g., colitis); severe allergies; and asthma. Dexamethasone-17-acetate is also used to treat certain types of cancer.

Uses:

1. Dexamethasone acetate (CAS No. 1177-87-3) is used to treat many inflammatory and autoimmune conditions, such as rheumatoid arthritis. It is useful to counteract allergic anaphylactic shock, if given in high doses. Dexamethasone acetate is used in transvenous screw-in cardiac pacing leads to minimize the inflammatory response of the myocardium.

2. In oncology, it is given to cancer patients undergoing chemotherapy, to counteract certain side-effects of their antitumor treatment. Dexamethasone can augment the antiemetic effect of 5-HT3 receptor antagonists like ondansetron.

Dexamethasone acetate is also used in certain hematological malignancies, especially in the treatment of multiple myeloma, in which dexamethasone is given alone or together with thalidomide (thal-dex) or lenalidomide, or a combination of Adriamycin (doxorubicin) and vincristine (VAD).

In brain tumours (primary or metastatic), Dexamethasone acetate is used to counteract the development of edema, which could eventually compress other brain structures. It is also given in cord compression where a tumor is compressing the spinal cord.

3. Dexamethasone acetate is the treatment for the very rare disorder of glucocorticoid resistance. In adrenal insufficiency and Addison's disease, it is prescribed when the person doesn't respond well to prednisone or methylprednisolone.

4. Dexamethasone acetate is used in the treatment of high altitude cerebral edema as well as pulmonary edema. It is commonly carried on mountain climbing expeditions to help climbers deal with altitude sickness.

5. Dexamethasone acetate has been used as an off-label pre-natal treatment for the symptoms of congenital adrenal hyperplasia (CAH) in female fetuses. Has also been used in the hope of enhancing sports performance. Dexamethasone acetate is also used in a diagnostic context, namely in its property to suppress the natural pituitary-adrenal axis.


6. Combined with marbofloxacin and clotrimazole, dDexamethasone acetate used to treat difficult ear infections, especially in dogs. It can also be combined with Trichlormethiazide to treat horses with swelling of distal limbs and general bruising.
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  CAS Registry Number:

1177-87-3

  Synonyms: ;Dexamethasoneacetate;Dexamethasone Acetate;Dexamethasone-17-acetate;(11beta,16alpha)-9-fluoro-11,21-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl acetate;(11beta,16alpha)-9-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl acetate;(16alpha)-9-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl acetate;(8xi,11beta,14xi,16alpha)-9-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl acetate;
  Molecular Formula: C24H31FO6
  Molecular Weight: 434.4977
  Molecular Structure: 1177-87-3 dexamethasone-21-acetate
  Hazard Symbols:  Xi:Irritant;
  Risk Codes: R43:;
  Safety Description: S36/37:;

  Company: Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd     [ China ]        
  Contact: hanhan
  Tel: +86-181-88931013
  Fax: +86-181-88931013
  Email: ychzkj@yuanchengtech.com
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