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Etomidate

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  Post Date: Jan 09,2018
  Expiry Date: Jul 08,2018
  Detailed Description: Cas No. :33125-97-2 Quantity: mass in stockKilograms
Specs:white powder
Price:negotiable USD Kilograms
Payment Method: T/T, Western Union,Moneygram and Bitcoin.
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Product Name: Etomidate
CAS NO: 33125-97-2
Appearance: white powder
MF: C14H16N2O2
Purity: 99%
Origin: China
Export market: Global
Grade: Pharmaceutical grade
Supply capacity: Mass in stock.
Usage: Health care products

Packing: Well disguised package to pass the customs.
Payment: T/T, Western Union,Moneygram and Bitcoin.
Shiping: EMS,HKEMS,FEDEX,DHL,TNT,Aramex,etc
Leading time: Within 24 hours after payment.
Delivery time: 3-7 work days

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Description:

Etomidate(marketed as Amidate) is a short-acting intravenous anaesthetic agent used for the induction of general anaesthesia and sedation for short procedures such as reduction of dislocated joints, tracheal intubation, and cardioversion. It was developed at Janssen Pharmaceutica in 1964 and was introduced as an intravenous agent in 1972 in Europe and in 1983 in the United States.

Medical uses
Sedation and anesthesia In emergency settings, etomidate is one of the most frequently used sedative hypnotic agents. It is used for conscious sedation and as a part of a rapid sequence induction to induce anaesthesia. It is used as an anaesthetic agent since it has a rapid onset of action and a safe cardiovascular risk profile, and therefore is less likely to cause a significant drop in blood pressure than other induction agents. In addition, etomidate is often used because of its easy dosing profile, limited suppression of ventilation, lack of histamine liberation and protection from myocardial and cerebral ischemia. Thus, etomidate is a good induction agent for people who are hemodynamically unstable. Etomidate also has interesting characteristics for people with traumatic brain injury because it is one of the only anesthetic agents able to decrease intracranial pressure and maintain a normal arterial pressure.

In those with sepsis, one dose of the medication does not appear to affect the risk of death.

Speech and memory test
Another use for etomidate is to determine speech lateralization in people prior to performing lobectomies to remove epileptogenic centres in the brain. This is called the etomidate speech and memory test, or eSAM, and is used at the Montreal Neurological Institute. However, only retrospective cohort studies support the use and safety of etomidate for this test.

Steroidogenesis inhibitor:
In addition to its action and use as an anesthetic, etomidate has also been found to directly inhibit the enzymatic biosynthesis of steroid hormones, including corticosteroids in the adrenal gland. As the only adrenal steroidogenesis inhibitor available for intravenous or parenteral administration, it is useful in situations in which rapid control of hypercortisolism is necessary or in which oral administration is unfeasible.

  CAS Registry Number:

33125-97-2


  Company: Hengyang Desen Biotechnology Co., Ltd.     [ China ]        
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