Home > Offer to Sell > Pharmaceuticals and Biochemicals > Antianaphylaxis(antihistamines) and antidotes > Exemestane
Exemestane
Inquiry
| Post Date: | Nov 05,2015 |
| Expiry Date: | May 03,2016 |
| Detailed Description: |
Cas No. :107868-30-4
Detailed Product Description
Healthly Raw Steroid Powders Anti Estrogen Aromasin Muscle Building Bulking Cycle Steroids Exemestane CAS 107868-30-4 Quick Details: •Product name: Exemestane •Alias: Aromasin ; Exemestan;Exemestane •Product Category: Pharmaceutical raw materials and intermediates •Assay: 98%min •CAS Registry Number:107868-30-4 •Molecular formula: C20H24O2 •Appearance: White or Almost White Crystalline Powder •Grade : Pharmaceutical Grade •Storage: Shading, confined preservation •Usage: Developed to help fight breast cancer, Aromasin is one of the most powerful estrogen suppressing compounds •Other drugs in same class: Anastrozole,Letrozole,Tamoxifen citrate,Exemestane Product Description: Exemestane is an oral steroidal aromatase inhibitor that is used in ER-positive breast cancer in addition to surgery and/or radiation in post-menopausal women. The main source of estrogen is the ovaries in premenopausal women, while in post-menopausal women most of the body's estrogen is produced via the conversion of androgens into estrogen by the aromatase enzyme in the peripheral tissues (i.e. adipose tissue like that of the breast) and a number of sites in the brain. Estrogen is produced locally via the actions of the aromatase enzyme in these peripheral tissues where it acts locally. Any circulating estrogen in post-menopausal women as well as men is the result of estrogen escaping local metabolism and entering the circulatory system. Applications: Exemestane is an irreversible, steroidal aromatase inactivator, structurally related to the natural substrate androstenedione. It acts as a false substrate for the aromatase enzyme, and is processed to an intermediate that binds irreversibly to the active site of the enzyme causing its inactivation, an effect also known as "suicide inhibition." By being structurally similar to enzyme targets, Exemestane permanently binds to the enzymes, preventing them from converting androgen into estrogen. Exemestane is taken in tablet form once a day. Patients can experience side effects like nausea, anxiety, shortness of breath, abdominal pain, bone pain, and chest pain. Side effects vary widely between patients and patients should report the side effects they experience to their doctors, as some may be indicators of dangerous complications. Shortness of breath and chest pain in particular are causes for concern in patients taking exemestane. |
| CAS Registry Number: | 107868-30-4 |
| Synonyms: | ;Exemestan;6-Methylenandrosta-1,4-diene-3,17-dione;10,13-Dimethyl-6-methylidene-7,8,9,10,11,12,13,14,15,16-decahydrocyclopenta[a]phenanthrene-;6-methylideneandrosta-1,4-diene-3,17-dione;(8ξ,9ξ,14ξ)-6-methylideneandrosta-1,4-diene-3,17-dione;Exemestane(Aromasin);Exemestone; |
| Molecular Formula: | C20H24O2 |
| Molecular Weight: | 296.4034 |
| Molecular Structure: | 
|
| Company: | Guangzhou Quanao Technology Co.,Limited [ China ] |
| Contact: | Jim |
| Tel: | +86-027-50755989 |
| Fax: | +86-027-50755989 |
| Email: | ycgc_int06@yccreate.com |
-
Disclaimer statement:The information and data included above have been realized by the enterprises and compiled by the staff, and are subject to change without notice to you. The Chemnet makes no warranties or representations whatsoever regarding the facticity, accuracy and validity of such information and data. In order to ensure your interest, we suggest you chose the products posted by our gold suppliers or VIP members.
