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Galanthamine Hydrobromide

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  Post Date: Jan 24,2013
  Expiry Date: Jan 24,2014
  Detailed Description: Cas No. :1953-04-4;69353-21-5 Quantity: 25kg/monthKilograms
Specs:99%
Price:negotiable USD Kilograms
Payment Method: T/T,L/C

Original Plant:Shorttube Lycoris

Specification:99%

Synonym(s) :Reminyl, Nivalin

Chemical Name:(4aS,6R,8aS)-6-Hydroxy-3-methoxy-11-methyl-5,6,9,10,11,12-hexahydro-4aH-benzofuro[3a,3,2-e,f][2]benzazepine hydrobromide

Test Method:HPLC

Molecular Formula:C17H21NO3.HBr;C17H22BrNO3

Molecular Weight:368.27

CAS No.: 1953-04-4


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EINECS No.: 217-780-5
Melting Point : 258~264 ℃
Solubility: Soluble in water,and slightly in alcohol.
Appearance: White to whitish crystal powder, oderless and tasteless.
Pharmacology Action: Galanthamine extract is specific, competitive and reversible acetylcholinesterase inhibitor. It is also an allosteric modulator at nicotinic cholinergic receptor sites potentiating cholinergic nicotinic neurotransmission. Both the acetylcholine and nicotine receptors have been suggested as areas related to cognitive impairment. Initially, Galanthamine extract was used in anesthesiology to antagonize the effects of non-depolarizing muscle relaxants, and since then it was rapidly introduced in other areas of medicine, i.e. neurology, ophthalmology, gastroenterology, intensive care and resuscitation, cardiology, physiotherapy.
Galanthamine extract is a product with broad therapeutic index, allowing "soft" manifestation of its effect with individual dosing depending on the particular case.
Several trials already showed that Galantamine 16 and 24 mg/day significantly benefits the cognitive, functional, and behavioral symptoms of AD as compared with placebo and proved also to be very effective in symptomatic treatment of senile dementia of Alzheimer's type.
Package:25kg/drum,0.01~1kg/vaccum bag, or depend on the customer's needs.
Shipment:Air Freight ,Ocean Freight,Express, or depend on the customer's needs.

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  CAS Registry Number:

1953-04-4;69353-21-5

  Synonyms: ;galantamine hydrobromide;Galantamine Hbr;galanthamine hydrobromide (1:1);(4aS,6R,8aS)-6-hydroxy-3-methoxy-11-methyl-5,6,9,10,11,12-hexahydro-4aH-[1]benzofuro[3a,3,2-ef][2]benzazepin-11-ium;Galanthamine HBr;5a,6,7,8,8a,12b-hexahydrogalanthamine hydrobromide (1:1);
  Molecular Formula: C17H22NO3Br
  Molecular Weight: 368.27058
  Molecular Structure: 1953-04-4;69353-21-5 galanthamine hydrobromide
  Hazard Symbols:  T:Toxic;
  Risk Codes: R25:;
  Safety Description: S22:;
S36/37/39:;
S45:;

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