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Phenylephrine hydrochloride

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  Post Date: Aug 14,2017
  Expiry Date: Aug 14,2018
  Detailed Description: Cas No. :61-76-7 Phenylephrine hydrochloride
CAS: 61-76-7
MF: C9H14ClNO2
MW: 203.67
EINECS: 200-517-3
Phenylephrine Hydrochloride Medical uses
Phenylephrine is used as a decongestant sold as an oral medicine or as a nasal spray. It is a common ingredient in over-the-counter decongestants in the United States. Other decongestants include oxymetazoline and pseudoephedrine. Phenylephrine is used as an alternative for pseudoephedrine in decongestant medicines due to pseudoephedrine's use in the illicit manufacture of methamphetamine. Its efficacy as an oral decongestant has been questioned, with several recent independent studies finding that it provided no more relief to sinus congestion than a placebo.
Phenylephrine is commonly used as a vasopressor to increase the blood pressure in unstable patients with hypotension, especially resulting from septic shock. Such use is common in anesthesia or critical-care practices; it is especially useful in counteracting the hypotensive effect of epidural and subarachnoid anesthetics, as well as the vasodilating effect of bacterial toxins and the inflammatory response in sepsis and systemic inflammatory response syndrome. The elimination half life of phenylephrine is about 2.5 to 3.0 hours. The clinical effects of a single intravenous bolus dose of phenylephrine are short lived and needs to be repeated every 10-15 minutes. Commonly the drug is given as a carefully titrated intravenous infusion with a syringe pump or volumetric pump.


  CAS Registry Number:

61-76-7

  Synonyms: ;3-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol hydrochloride;L-Phenylephrine hydrochloride;(R)-3-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol hydrochloride;Phenylephrine HCL;PHENYLEPHRINE HYDROCHLORIDE;(R)-(-)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride;d-(-)-phenylephrinehydrochloride;Phenylephrine Hydrochloride;
  Molecular Formula: C9H15Cl2NO2
  Molecular Weight: 240.1269
  Molecular Structure: 61-76-7 L(-)-Phenylephrine hydrochloride
  Hazard Symbols:  Xn:Harmful;
  Risk Codes: R22:;
R36/37/38:;
  Safety Description: S26:;
S37/39:;

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