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Saxagliptin

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  Post Date: Feb 04,2015
  Expiry Date: Feb 04,2016
  Detailed Description: Cas No. :361442-04-8 Product name: Saxagliptin
CAS: 361442-04-8
Molecular formula: C18H25N3O2
Molecular weight: 315.414
Description: Saxagliptin (rINN), previously identified as BMS-477118, is a new oral hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Early development was solely by Bristol-Myers Squibb; in 2007 AstraZeneca joined with Bristol-Myers Squibb to co-develop the final compound and collaborate on the marketing of the drug. In June 2008, it was announced that Onglyza would be the trade name under which saxagliptin will be marketed.
While used for type 2 diabetes the evidence does not show a change in hard end points such as the risk of heart attacks or strokes.

  CAS Registry Number:

361442-04-8

  Synonyms: ;BMS 477118;Onglyza;(1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile;(1S,3S,5S)-2-[2(S)-Amino-2-(3-hydroxyadamantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile;
  Molecular Formula: C18H25N3O2
  Molecular Weight: 315.41
  Molecular Structure: 361442-04-8 Saxagliptin

  Company: AUSMAUCO BIOTECH CO., LIMITED     [ China ]        
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