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Top Quality Chemical Intermediates of Bimatoprost 155206-00-1

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  Post Date: Dec 10,2016
  Expiry Date: Dec 10,2017
  Detailed Description: Cas No. :155206-00-1 Quantity: 5Metric Tons
Specs:USP
Price:1 USD Metric Tons
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Top Quality Chemical Intermediates of Bimatoprost 155206-00-1

Quick Details:

Name:Bimatoprost
Synonyms:N-ETHYL-9ALPHA,11ALPHA,15S-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROSTA-5Z, 13E-DIEN-1-AMIDE; ; BIMATOPROST(TM); 17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA ETHYL AMIDE; BIMATOPROST; 17-phenyl-tri-norprostaglandin f2-ethyl amide; (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-ethylhept-5-enamide; (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl}-N-ethylhept-5-enamide; (5E)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl}-N-ethylhept-5-enamide
CAS No.:155206-00-1
MF:C25H37NO4
MW:415.5656
Molecular Structure:

Purity:99%
Appearance:White crystal

Description:

Bimatoprost (marketed in the U.S., Canada and Europe by Allergan, ) is aprostaglandin analog/prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. It reduces intraocular pressure (IOP) by increasing the outflow of aqueous fluidfrom the eyes. In December 2008, the indication to lengthen eyelashes was approved by the U.S. Food and Drug Administration (FDA); the cosmetic formulation of bimatoprost is sold as Latisse In 2008-2011, at least three case series suggested that bimatoprost has the ability to reduce adipose (fat) tissue.

Usage:
Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. It reduces intraocular pressure (IOP) by increasing the outflow of aqueous fluid from the eyes.
Packing foil bag or as required

COA:

TEST SPECIFICATIONS RESULTS
Appearance White to yellow crystalline powder White crystalline powder
Identification A. Should meet the requirement Conforms
B. Should meet the requirement Conforms
Impurity A ≤0.5% N.D.
Impurity B ≤0.3% 0.075%
Loss on drying ≤0.5% 0.085%
Residue on Ignition ≤0.1% 0.045%
Residual solvent Ethanol≤0.5% 0.026%
Ethyl acetate≤0.5% N.D.
Tetrahydrofuran≤0.072% N.D.
Heavy Metal ≤20ppm Conforms
Assay 98.0%~102.0% (Calculated on the dried basis)

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  CAS Registry Number:

155206-00-1

  Synonyms: ;N-Ethyl-9Alpha,11Alpha,15S-Trihydroxy-17-Phenyl-18,19,20-Trinor-Prosta-5Z, 13E-Dien-1-Amide;LUMIGAN;Bimatoprost(TM);17-phenyl TRINOR prostaglandin F2ALPHA ethyl amide;Bimatoprost(LUMIGAN);17-phenyl-tri-norprostaglandin f2α-ethyl amide;(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-ethylhept-5-enamide;(5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl}-N-ethylhept-5-enamide;(5E)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl}-N-ethylhept-5-enamide;
  Molecular Formula: C25H37NO4
  Molecular Weight: 415.5656
  Molecular Structure: 155206-00-1 Bimatoprost

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