Home > Offer to Sell > Intermediates > Pharmaceutical intermediates > Toremifene Citrate

Toremifene Citrate

Inquiry
  Post Date: Sep 12,2015
  Expiry Date: Sep 11,2016
  Detailed Description: Cas No. :89778-27-8 Quantity: 2000Kilograms
Specs:ISO
Price:1 USD Kilograms
Payment Method: Western Union, MoneyGram, Bank Transfer
Molecular Formula: C26H28ClNO·C6H8O7
Molecular Weight: 598.09
assay:99%
Sky pe:(live:hanhan9937)

Melting Point: 158-164 ºC
Boiling Point: 535.1 ºC at 760 mmHg
Density: 1.045g/cm3
Refractive index: 1,416-1,418
Sky pe:(live:hanhan9937)

Product Details:Place of Origin: China
Brand Name: Yuancheng
Certification: agnes-pharmade 111
Payment & Shipping Terms:Minimum Order Quantity: 100ml
Price: Negotiable
Packaging Details: Foil bag or as requirement
Delivery Time: 24 hours after payment
Payment Terms: Western Union, MoneyGram, Bank Transfer
Supply Ability: 2000ml/month
Usage: As anti-cancer drugs
HS Code: 2937290090



Application:

Toremifene citrate is an oral selective estrogen receptor modulator (SERM) which helps oppose the actions of estrogen in the body. Licensed in the United States under the brand name Fareston, toremifene citrate is FDA-approved for use in advanced (metastatic) breast cancer. It is also being evaluated for prevention of prostate cancer under the brand name Acapodene.

It has already been covered that Toremifene is a SERM, and serves to block Estrogen at various receptor sites in certain tissues within the body (breast tissue in particular). As a layman explanation, Toremifene pretends to be a 'fake' Estrogen that occupies Estrogen receptors within breast tissue. With these receptors occupied by Toremifene, real Estrogen cannot perform their jobs there.

Toremifene does not reduce total blood plasma levels of Estrogen. In addition to being antagonistic to Estrogen receptors in breast tissue, it is also antagonistic to Estrogen at the hypothalamus gland (this essentially 'tricks' the hypothalamus into thinking there is little or no circulating Estrogen levels in the body, causing it to increase its manufacture of Testosterone so that it can utilize aromatization to restore these levels.

Toremifene is also agonistic to Estrogen receptors in other tissues in the body (within the liver in particular). This means that whileToremifene will act as an anti-estrogen in breast tissue and the hypothalamus, it will act as an Estrogen within the liver. This can have beneficial impacts especially during an anabolic steroid cycle, such as improving and shifting cholesterol levels into a more favorable range.


Our advantages:
1. Best prices with satisfied quality.
2. Rich experienced in delivering the parcels to you.
3. Enough stock ensure the prompt delivery time.
4. Good after-sales service.
5. Package will be reshipped if sent failed.
6. Specials are possible when the order is big enough.

• We specialized in pharmaceutical chemicals' production for over 10 years,
• very rich experience in custom,we have professinal packing team,and fastest delivery time,
• packing pictures and tracking codes will be sent to you within 48 hours after your order.
• have reshipping policy to many countries.

hnzz01 at ycgmp dot com

Sky pe:(live:hanhan9937)

  CAS Registry Number:

89778-27-8

  Synonyms: ;(z)-4-chloro-1,2-diphenyl-1-(4-(2-(n,n-dimethylamino)ethoxy)phenyl)-1-butene ;2-(4-(4-chloro-1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimethyl-ethanamin(z)-ethanamin ;2-hydroxy-1,2,3-propanetricarboxylate(1:1) ;fareston ;fc1157a ;nk622 ; ;(z)-2-[4-(4-chloro-1,2-diphenyl-1-butenyl)phenoxy]-n,n-dimethyl-ethanamine 2-hydroxy-1,2,3-propanetricarboxylate ;TROPISETRON CITRATE ;2-[4-[(1Z)-4-CHLORO-1,2-DIPHENYL-1-BUTENYL]PHENOXY]-N,N-DIMETHYLETHANAMINE;
  Molecular Formula: C26H28ClNO·C6H8O7
  Molecular Weight: 598.09
  Molecular Structure: 89778-27-8 TOREMIFENE CITRATE

  Company: Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd     [ China ]        
  Contact: hanhan
  Tel: +86-181-88931013
  Fax: +86-181-88931013
  Email: ychzkj@ycgmp.com
Disclaimer statement:The information and data included above have been realized by the enterprises and compiled by the staff, and are subject to change without notice to you. The Chemnet makes no warranties or representations whatsoever regarding the facticity, accuracy and validity of such information and data. In order to ensure your interest, we suggest you chose the products posted by our gold suppliers or VIP members.